Protein Alignment Hs6st and HS6ST2

DIOPT Version :10

• Sequence 1: NP_524409.2
• Gene: Hs6st / 42380
• FlyBaseID: FBgn0038755
• Length: 462
• Species: Drosophila melanogaster
• Sequence 2: NP_001070656.1
• Gene: HS6ST2 / 90161
• HGNCID: 19133
• Length: 645
• Species: Homo sapiens
• Alignment Length: 340
• Identity: 172/340 - (50%)
• Similarity: 224/340 - (65%)
• Gaps: 50/340 - (14%)

  Fly   141 FDMDGHDVMVFLHIQKTGGTSFGRHLVRDLDLKRPCECQRQRKRCYCFRPHRNENWLFSRYSTGW 205
            ||:.|.|::|||||||||||:|||||||::.|::||||:..:|:|.|.||.:.|.|||||:||||
Human   221 FDIKGDDLIVFLHIQKTGGTTFGRHLVRNIQLEQPCECRVGQKKCTCHRPGKRETWLFSRFSTGW 285

  Fly   206 KCGLHADWTELTSCV--------DVEL----------------DK------NEG----------E 230
            .||||||||||||||        |..|                ||      |.|          .
Human   286 SCGLHADWTELTSCVPSVVDGKRDARLRPSRWRIFQILDAASKDKRGSPNTNAGANSPSSTKTRN 350

  Fly   231 TAK--RRYFYISLLRQPIARYMSEYRHVRRGATWKGSRHWCLGRQATAAELPACYKGKDWLDVDL 293
            |:|  :.:.||::||.|::||:||:|||:||||||.|.|.|.||..|:.|||:||.|.||....|
Human   351 TSKSGKNFHYITILRDPVSRYLSEWRHVQRGATWKASLHVCDGRPPTSEELPSCYTGDDWSGCPL 415

  Fly   294 DQFAGCESNLAANRQTRMLADLALVGCYNKSSMPAHERDRVMLASAKRNLAAMAYFGLTEYQKMS 358
            .:|..|..|||.|||.|||:||.||||||.|.||..:|::|:|.|||.||..||:|||||:|:.:
Human   416 KEFMDCPYNLANNRQVRMLSDLTLVGCYNLSVMPEKQRNKVLLESAKSNLKHMAFFGLTEFQRKT 480

  Fly   359 QYIFEETFNLRFAIPFEQHNTTISATAVQNLRPDQKRRIEKLNSLDIELYAFAKTLLFQRF---- 419
            ||:||:|||:.|..||.|:||| .|::|: :..:.::|||.||.||:|||::||.|..||:
Human   481 QYLFEKTFNMNFISPFTQYNTT-RASSVE-INEEIQKRIEGLNFLDMELYSYAKDLFLQRYQFMR 543

  Fly   420 --EHLKAKDTNFEQR 432
              ||.:|:....|||
Human   544 QKEHQEARRKRQEQR 558

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hs6st	NP_524409.2	Sulfotransfer_2	144..411	CDD:427369	159/308 (52%)
HS6ST2	NP_001070656.1	Sulfotransfer_2	225..531	CDD:427369	159/307 (52%)