DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Hs6st and Hs6st1

DIOPT Version :9

Sequence 1:	NP_001262750.1	Gene:	Hs6st / 42380	FlyBaseID:	FBgn0038755	Length:	462	Species:	Drosophila melanogaster
Sequence 2:	NP_001101680.1	Gene:	Hs6st1 / 316325	RGDID:	1309218	Length:	329	Species:	Rattus norvegicus

Alignment Length:	295	Identity:	164/295 - (55%)
Similarity:	218/295 - (73%)	Gaps:	5/295 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly   143 MDGHDVMVFLHIQKTGGTSFGRHLVRDLDLKRPCECQRQRKRCYCFRPHRNENWLFSRYSTGWKC 207
            |.|.||:|||||||||||:||||||:::.|:.||:|:..:|:|.|:||:|.|.|||||:||||.|
  Rat     1 MKGDDVIVFLHIQKTGGTTFGRHLVQNVRLEVPCDCRPGQKKCTCYRPNRRETWLFSRFSTGWSC 65

  Fly   208 GLHADWTELTSCVDVELDKNE--GETAKRRYFYISLLRQPIARYMSEYRHVRRGATWKGSRHWCL 270
            ||||||||||:||...||:.:  |..:.|:::||:|||.|::||:||:|||:||||||.|.|.|.
  Rat    66 GLHADWTELTNCVPGVLDRRDPAGLRSPRKFYYITLLRDPVSRYLSEWRHVQRGATWKTSLHMCD 130

  Fly   271 GRQATAAELPACYKGKDWLDVDLDQFAGCESNLAANRQTRMLADLALVGCYNKSSMPAHERDRVM 335
            ||..|..|||.||:|.||....|.:|..|..|||.|||.||||||:||||||.|.:|..:|.:::
  Rat   131 GRTPTPEELPPCYEGTDWSGCTLQEFMDCPYNLANNRQVRMLADLSLVGCYNLSFIPESKRAQLL 195

  Fly   336 LASAKRNLAAMAYFGLTEYQKMSQYIFEETFNLRFAIPFEQHNTTISATAVQNLRPDQKRRIEKL 400
            |.|||:||..||:|||||:|:.:||:||.||||:|..||.|:|:| .|..|: :..|..|.||:|
  Rat   196 LESAKKNLRGMAFFGLTEFQRKTQYLFERTFNLKFIRPFMQYNST-RAGGVE-VDEDTIRHIEEL 258

  Fly   401 NSLDIELYAFAKTLLFQRFEHLKAKDTNFEQRYAN 435
            |.||::||.:||.|..||:::.:..:.. |||..|
  Rat   259 NDLDMQLYDYAKDLFQQRYQYKRQLERR-EQRLRN 292

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Hs6st	NP_001262750.1	Sulfotransfer_2	144..410	CDD:281554	154/267 (58%)
Hs6st1	NP_001101680.1	Sulfotransfer_2	3..268	CDD:281554	154/266 (58%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166353805
Domainoid	1	1.000	329	1.000	Domainoid score	I1124
eggNOG	1	0.900	-	-		E1_KOG3955
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H75051
Inparanoid	1	1.050	339	1.000	Inparanoid score	I2294
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1167623at2759
OrthoFinder	1	1.000	-	-		FOG0001176
OrthoInspector	1	1.000	-	-		otm44872
orthoMCL	1	0.900	-	-		OOG6_104471
Panther	1	1.100	-	-	O	PTHR12812
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X1002
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	15	14.760