DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Hs6st and hs6st3

DIOPT Version :9

Sequence 1:	NP_001262750.1	Gene:	Hs6st / 42380	FlyBaseID:	FBgn0038755	Length:	462	Species:	Drosophila melanogaster
Sequence 2:	XP_002935690.1	Gene:	hs6st3 / 100486788	XenbaseID:	XB-GENE-987159	Length:	422	Species:	Xenopus tropicalis

Alignment Length:	328	Identity:	164/328 - (50%)
Similarity:	219/328 - (66%)	Gaps:	27/328 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly   128 GLSYEDVLNDDFQ---------------FDMDGHDVMVFLHIQKTGGTSFGRHLVRDLDLKRPCE 177
            |...||.:...||               |::.|.||:|||||||||||:|||||||::.|::||:
Frog    66 GEDAEDCIPPKFQPTYNFLAKDLARFVDFNIKGDDVIVFLHIQKTGGTTFGRHLVRNIHLEQPCD 130

  Fly   178 CQRQRKRCYCFRPHRNENWLFSRYSTGWKCGLHADWTELTSCVDVELDKNEGETAKRRYFYISLL 242
            |:..:|:|.|.||.:.|.|||||:||||.|||||||||||:||...::|.:.....|.::||::|
Frog   131 CKPGQKKCTCHRPGKKETWLFSRFSTGWSCGLHADWTELTNCVPAIMEKKDSLRNHRNFYYITML 195

  Fly   243 RQPIARYMSEYRHVRRGATWKGSRHWCLGRQATAAELPACYKGKDWLDVDLDQFAGCESNLAANR 307
            |.|::||:||::||:||||||.|.|.|.||..|..|||.||.|.||..|.|.:|..|..|||.||
Frog   196 RDPVSRYLSEWKHVQRGATWKASLHVCDGRSPTPDELPTCYVGDDWSGVTLQEFMDCSYNLANNR 260

  Fly   308 QTRMLADLALVGCYNKSSMPAHERDRVMLASAKRNLAAMAYFGLTEYQKMSQYIFEETFNLRFAI 372
            |.||||||:||||||.:.|...||:.::|.|||.||..||::||||:|:.:||:||.||||:|..
Frog   261 QVRMLADLSLVGCYNLTFMNESERNHILLQSAKNNLKNMAFYGLTEFQRKTQYLFERTFNLKFIS 325

  Fly   373 PFEQHNTTISATAVQNLRPDQ--KRRIEKLNSLDIELYAFAKTLLFQRF------EHLKAKDTNF 429
            ||.|.|    :|...|:..|:  :.||::||.||::||.:||.|..|||      ||.:.::...
Frog   326 PFTQFN----STRASNVDIDERSRERIKELNYLDVQLYEYAKDLFLQRFQYTRQQEHQRKREKRK 386

  Fly   430 EQR 432
            |:|
Frog   387 EER 389

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Hs6st	NP_001262750.1	Sulfotransfer_2	144..410	CDD:281554	148/267 (55%)
hs6st3	XP_002935690.1	Sulfotransfer_2	98..361	CDD:281554	148/266 (56%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1167623at2759
OrthoFinder	1	1.000	-	-		FOG0001176
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3281
SonicParanoid	1	1.000	-	-		X1002
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	4.040