DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment mira and AT1G05320

DIOPT Version :9

Sequence 1:	NP_477291.1	Gene:	mira / 42379	FlyBaseID:	FBgn0021776	Length:	829	Species:	Drosophila melanogaster
Sequence 2:	NP_001030972.2	Gene:	AT1G05320 / 837031	AraportID:	AT1G05320	Length:	790	Species:	Arabidopsis thaliana

Alignment Length:	780	Identity:	185/780 - (23%)
Similarity:	318/780 - (40%)	Gaps:	154/780 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    52 ERKEQIEKFFKDAVRFASSSKEAKEFAIPKEDKKSKGLRLFRTP----SLPQRLRFRPTPSHTDT 112
            |:.|:..|..:||::.  ...:.||....||.....||.|..:.    .|..|:|.
plant    55 EKAEKQLKSLEDALQL--HDVKHKELTEVKEAFDGLGLELENSRKKMIELEDRIRI--------- 108

  Fly   113 ATGSGSGASTAASTPLHSAATTPVKEAKSASRLKGKEALQYEIRHKNELIESQLSQLDVLRRHVD 177
               |...|.........||:....|...|..|....:||..:...:|.::|.:|..|:.|...|.
plant   109 ---SALEAEKLEELQKQSASELEEKLKISDERYSKTDALLSQALSQNSVLEQKLKSLEELSEKVS 170

  Fly   178 QLKEAEAKLREEHELAT-------SKTDRLIEALTSENLSHKALNE------QMGQEHADL---- 225
            :||.|.....||.:.::       .|..:|..:|...:..:..|.|      |.|.||.|:
plant   171 ELKSALIVAEEEGKKSSIQMQEYQEKVSKLESSLNQSSARNSELEEDLRIALQKGAEHEDIGNVS 235

  Fly   226 ------LERLAAMEQQLQQQHDEHERQVEALVAESEALRLANELLQTANEDRQKVEEQLQAQLSA 284
                  |:.|....|...::.:|..:.:||:..::.:|...   |..|.|..:.:.|.|.|.:..
plant   236 TKRSVELQGLFQTSQLKLEKAEEKLKDLEAIQVKNSSLEAT---LSVAMEKERDLSENLNAVMEK 297

  Fly   285 LQAD----VAQAREHCSLEQAKTAENIELVENLQKTNASLLADVVQLK-QQIEQDALSYGQEAKS 344
            |::.    ..||||   :::| |..:||| |.|.|.:        :|| |:..:|..|...||||
plant   298 LKSSEERLEKQARE---IDEA-TTRSIEL-EALHKHS--------ELKVQKTMEDFSSRDTEAKS 349

  Fly   345 CQAELECLKVERNTLKNDLANKCTLIRSLQDELLDKNCEIDAHCDTIRQLC-----REQARHTEQ 404
            ...:.:.|:.:....:..||..|....|||:||...:.|.:...||..||.     .|....:|:
plant   350 LTEKSKDLEEKIRVYEGKLAEACGQSLSLQEELDQSSAENELLADTNNQLKIKIQELEGYLDSEK 414

  Fly   405 QQAVAKVQQQVESDLESAVEREKSYWRA-ELDKRQKLAEN---ELIKIELEKQDVMVLLETTNDM 465
            :.|:.|:.|: :::.:..:.:.||:... |..|||.|..:   :..|:|:|  :.::.|.|....
plant   415 ETAIEKLNQK-DTEAKDLITKLKSHENVIEEHKRQVLEASGVADTRKVEVE--EALLKLNTLEST 476

  Fly   466 LRMRDEKLQKCEEQLRNG--IDYYIQLSDALQQQLVQLKQDMAK-TITEKYNYQ----LTLTNTR 523
            :    |:|:|     .||  .:..|:|:..|..|..:.....|| ::.|...||    |.:|...
plant   477 I----EELEK-----ENGDLAEVNIKLNQKLANQGSETDDFQAKLSVLEAEKYQQAKELQITIED 532

  Fly   524 ATVNILMERLKKSDADVEQYRAELESVQLAKGALEQSYLVLQADAEQLRQQLTESQDALNALRSS 588
            .|..:..||        |:.|:::.|::..|..:.:.|       :..:.:|.:.|..|...:|.
plant   533 LTKQLTSER--------ERLRSQISSLEEEKNQVNEIY-------QSTKNELVKLQAQLQVDKSK 582

  Fly   589 SQTLQSEVSLKESLLHELLAGEAETLAKFNQIANSFQERIDGDAQLA-----HYHELRRKDETRE 648
            |..:.|::    ..|..|:|.::...:||.|:....:|.::..|:|.     |.|:...:|...|
plant   583 SDDMVSQI----EKLSALVAEKSVLESKFEQVEIHLKEEVEKVAELTSKLQEHKHKASDRDVLEE 643

  Fly   649 -------------AYMVDMKKAL----DEFATVLQFAQLELDNKEQMLVKVREECEQL--KLENI 694
                         ..:.:.|:||    .|....|:.:|.|||.|:.::|.:..:..:|  |::..
plant   644 KAIQLHKELQASHTAISEQKEALSHKHSELEATLKKSQEELDAKKSVIVHLESKLNELEQKVKLA 708

  Fly   695 ALKSKQPGSASLLGTPGKAN----RSNTTDLE-------KIEDLLCDSELRSD---CEKITTWLL 745
            ..|||:..|.      ||..    :|..:||.       ||:..| |:...|.   .:|..||.|
plant   709 DAKSKETEST------GKEEEVEVKSRDSDLSFSNPKQTKIKKNL-DAASSSGHVMIQKAETWHL 766

Fly 746 745
plant 767 766

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
mira	NP_477291.1	SH3_and_anchor	<163..272	CDD:275056	30/131 (23%)
AT1G05320	NP_001030972.2	Smc	101..>763	CDD:224117	170/727 (23%)
		DUF4559	<184..322	CDD:291771	31/144 (22%)
		CASP_C	<538..>574	CDD:285395	8/50 (16%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000