Protein Alignment CG4459 and Slc22a7

DIOPT Version :9

• Sequence 1: NP_650850.1
• Gene: CG4459 / 42377
• FlyBaseID: FBgn0038753
• Length: 632
• Species: Drosophila melanogaster
• Sequence 2: NP_445989.2
• Gene: Slc22a7 / 89776
• RGDID: 621699
• Length: 535
• Species: Rattus norvegicus
• Alignment Length: 549
• Identity: 127/549 - (23%)
• Similarity: 225/549 - (40%)
• Gaps: 109/549 - (19%)

  Fly    19 DVVEQVNGSFGRWQLRTILLIFLCKIPSAWFTAIIIYTAPYPWKGELVCHPADWNVSRSQTEHVD 83
            |::::| |.||.:|||.::|:.|.::.......:.::.|..|      .|......:.:...|.|
  Rat     5 DLLDKV-GGFGPFQLRNLVLMALPRMLLPMHFLLPVFMAAVP------AHHCALPGAPANLSHQD 62

  Fly    84 RNHPLWQDA---RSTDRLFNVDVCNAYSNSLARGFVRSHGQEWNASQSKEPGGQS-SLPCEH--V 142
                ||.:|   |.||..|:..:..||..::....:   |.|  .|.|.||.|:. ::||..  .
  Rat    63 ----LWLEAHLPRETDGSFSSCLRFAYPQTVPNVTL---GTE--VSNSGEPEGEPLTVPCSQGWE 118

  Fly   143 EHRTDYKSLI-SQFDLICSRRVLVALTQSFHALGALIGGLMAYSALKKISPRRLMLLGMIGQIFC 206
            ..|:::.|.| :::||:|.:|.|..:|.:...:|.|:|.::......:...|||:|:..:..:..
  Rat   119 YDRSEFSSTIATEWDLVCQQRGLNKITSTCFFIGVLVGAVVYGYLSDRFGRRRLLLVAYVSSLVL 183

  Fly   207 GNLTGLVDTYQLHIYFRCLTSIFCA---LMYTSGQFILNDITSGKARIIVVTLSELFWSMGLVLL 268
            |.::.....|.:.:..|.||....|   ::....:....|:   :.|.:...:|.:|||.|::||
  Rat   184 GLMSAASINYIMFVVTRTLTGSALAGFTIIVLPLELEWLDV---EHRTVAGVISTVFWSGGVLLL 245

  Fly   269 PAISIYFDNWSYLYVAISSSL---IVLVWLHRWIADAPRWLLQHQRVEAALRQLLESATYNNRKV 330
            ..:.....:|.:|.:|.:...   |:.:|   |:.::.||||...|||.|.:.||..|..|.|.|
  Rat   246 ALVGYLIRSWRWLLLAATLPCVPGIISIW---WVPESARWLLTQGRVEEAKKYLLSCAKLNGRPV 307

  Fly   331 ------PLTLDVQLTMYANDLDQKSKQKHSYCQVWDGETKRSQLVYIHL----IWGGAMVLYNII 385
                  ...|:..:||      :::.|:.||..::    :.|||.:|.|    :|.|....|..:
  Rat   308 GEGSLSQEALNNVVTM------ERALQRPSYLDLF----RTSQLRHISLCCMMVWFGVNFSYYGL 362

  Fly   386 LLMIRNLGAQQVHVNTAAMGFAEMVGLFVGLYLILYTRRHWRWAGNLMIIAGLSTYLIWLLPETE 450
            .|.:..||. .|:......|..|:....:..:|:....|....||  |::....|:...||...|
  Rat   363 TLDVSGLGL-NVYQTQLLFGAVELPSKIMVYFLVRRLGRRLTEAG--MLLGAALTFGTSLLVSLE 424

  Fly   451 RNS--------------------------------RRVGLELV-------------------FWL 464
            ..|                                |:.||.|.                   .||
  Rat   425 TKSWITALVVVGKAFSEAAFTTAYLFTSELYPTVLRQTGLGLTALMGRLGASLAPLAALLDGVWL 489

  Fly   465 ILKIANSASIAVLTTCTSEIVSKEKRVVL 493
            :|.......||::..||:.::.:.|:..|
  Rat   490 LLPKVAYGGIALVAACTALLLPETKKAQL 518

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4459	NP_650850.1	2A0119	26..536	CDD:273328	125/542 (23%)
		MFS	164..540	CDD:119392	87/397 (22%)
Slc22a7	NP_445989.2	2A0119	11..521	CDD:273328	125/542 (23%)
		MFS	144..511	CDD:119392	84/385 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166347107
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.840