DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG4459 and OCT6

DIOPT Version :9

Sequence 1:	NP_650850.1	Gene:	CG4459 / 42377	FlyBaseID:	FBgn0038753	Length:	632	Species:	Drosophila melanogaster
Sequence 2:	NP_173087.1	Gene:	OCT6 / 838207	AraportID:	AT1G16370	Length:	521	Species:	Arabidopsis thaliana

Alignment Length:	585	Identity:	118/585 - (20%)
Similarity:	210/585 - (35%)	Gaps:	150/585 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MTDSQSMGSIPRKSSPELD-VVEQVNGSFGRWQLRTILLIFLCKIPSAWFTAIIIYTAPYPWKGE 64
            :||...:....|..:...| :|||....||.||...|.|:.|..:..|....|.:||..||
plant    13 LTDDSGVNEKTRLEALTFDKIVEQSLSDFGFWQFFQISLVGLALLFDAQQIFITVYTDAYP---- 73

  Fly    65 LVCHPADWNVSRSQTEHVDRNHPLWQDARSTDRLFNVDVCNAYSNSLARGFVRSHGQEWNASQSK 129
                  .|:.         .||.:...:.|       |:|     .|.|.     ..||:
plant    74 ------TWHC---------LNHTICDPSAS-------DIC-----KLPRS-----AWEWD----- 101

  Fly   130 EPGGQSSLPCEHVEHRTDYKSLISQFDLICSRRVLVALTQSFHALGALIGG-LMAYSALKKISPR 193
              ||...            ||:||:|.|.||..:|..:..|...:||::|| .:|......:..:
plant   102 --GGSQG------------KSVISEFGLECSSSLLRGMPSSAFYIGAIVGGFFLALIPDDSLGRK 152

  Fly   194 RLMLLGMIGQIFCGNLTGLVDTYQLHIYFRCLTSIFCALMYTSGQFILNDITSGKARIIVVTLSE 258
            :|:|.    ..|..::|.:...:..:::           :||..:||:....|......:|.:||
plant   153 KLVLF----STFAMSITSISVIFSTNVW-----------IYTFLKFIIGFSRSQTWSYALVLISE 202

  Fly   259 LF---WSMGLVLLP--------------AISIYFDNWSYLYVAIS-SSLIVLVWLHRWIADAPRW 305
            ..   |.....::|              |......:|.|||:..| .::...::|:.:..::|||
plant   203 RVSTRWRPRATMIPFTLFVLGFMSLSGIAFLAQDSSWRYLYLYTSVPAVFYCIFLYLFALESPRW 267

  Fly   306 LLQHQRVEAAL----------RQLLESATYNNRKVPLTLD--VQLTMYANDLDQKSKQKHSYCQV 358
            |....:.:.|:          :..|||..   .|:||..:  .|...|:        .|..:.:.
plant   268 LHMQGKDKEAIDVLTKMSPKEKAYLESVV---SKLPLKQENFEQAPTYS--------IKDFFFRK 321

  Fly   359 WDGETKRSQLVYIHLIWGGAMVLYNIILLMIRNLGAQQVHVNTAAMGFAEMVGLFVGLYLILYT- 422
            |   ..|..||.:.:::|..:..|.:      .|.|:.:.||   :..:|.:...|.|...:.|
plant   322 W---AFRRILVVMIIMFGLGISYYGV------PLAARDIDVN---IYLSETLNALVELPTFVITP 374

  Fly   423 ---RRHWRWAGNLM--IIAGLSTYLIWLLPETERNSRRVGLELVFWLILKIANSA----SIAVLT 478
               .|..|.:..|:  ::.|.|..|.::|....:.......||..:...:|..:.    .:.:..
plant   375 ILLERFNRRSSVLVNTLLGGASGVLCFVLSILGKTEIAFAFELGTFFCARIGFNLMAVFMVEMFP 439

  Fly   479 TCTSEIVSKEKRVVLMLSVISFSRVCLLFCPFLSCLTVIHHLVPITILATMGWIYGLALRRLNRY 543
            ||.     :....::....:.....|   ||.::.   |...:|....|    |:|:|:..|..:
plant   440 TCV-----RSSATMMFRQALVVGGAC---CPLIAS---IGRYIPSVSFA----IFGIAMSGLGMF 489

Fly 544 543
plant 490 489

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4459	NP_650850.1	2A0119	26..536	CDD:273328	109/550 (20%)
CG4459	NP_650850.1	MFS	164..540	CDD:119392	77/416 (19%)
OCT6	NP_173087.1	MFS_OCT_plant	88..494	CDD:340936	95/491 (19%)
OCT6	NP_173087.1	xylE	<220..>314	CDD:182225	20/104 (19%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24064
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.100