Protein Alignment CG4459 and slc22a7a

DIOPT Version :10

• Sequence 1: NP_650850.1
• Gene: CG4459 / 42377
• FlyBaseID: FBgn0038753
• Length: 632
• Species: Drosophila melanogaster
• Sequence 2: NP_001077330.1
• Gene: slc22a7a / 794188
• ZFINID: ZDB-GENE-050506-52
• Length: 560
• Species: Danio rerio
• Alignment Length: 619
• Identity: 136/619 - (21%)
• Similarity: 248/619 - (40%)
• Gaps: 87/619 - (14%)

  Fly    19 DVVEQVNGSFGRWQLRTILLIFLCKI--PSAWFTAIIIYTAPYPWKGELVCHPADWNVSRSQTEH 81
            ||:.:: |.|.::|...:.:::|.::  |..:.....|...| |....|......::.|.::.|.
Zfish     5 DVLREI-GGFNKFQFLVLYILWLPRVILPLHFLLHNFISGVP-PHHCALPRLDGRFSASGAEKEE 67

  Fly    82 VDRNHPLWQDARSTDRLFNVDVCNAYSNSLARGFVRSHGQEWNASQSKEPGGQS--SLPCEH--V 142
            :.:...| ...|::|..::  .|..|  ::...|      :.|...|...|.:|  |:||::  |
Zfish    68 LAQIVAL-GIPRNSDGSYS--SCKMY--TMPMDF------DLNGDLSVLYGNRSNVSVPCQNGWV 121

  Fly   143 EHRTDYKS-LISQFDLICSRRVLVALTQSFHALGALIGGLMAYSALKKISPRRLMLLGMIGQIFC 206
            ..|:.:.| ..:::||:|..:.|.....:|..:|..:|.::......|...:.::.:..:.....
Zfish   122 YDRSQFTSTTATEWDLVCDNKKLNQALATFFFIGVTMGAVVFGQLSDKFGRKPMIQVSFVSSAVF 186

  Fly   207 GNLTGLVDTYQLHIYFRCLTSIFCALMYTSGQFILNDITSGKARIIVVTLSELFWSMGLVLLPAI 271
            |.:.....:|.:....|.|.......|..:...:..:.|..|.|....|:..|.||:|.:||..:
Zfish   187 GIIEAFSSSYVMFAIARTLCGFALTGMSITTVALCVEWTDVKHRTFTGTIISLGWSVGNMLLALL 251

  Fly   272 SIYFDNWSYLYVAISSSLIVLVWLHRWIADAPRWLLQHQRVEAALRQLLESATYNNR-KVPLTLD 335
            :....:|.:|.:.::|..:|.:....||.::.||||.:.|||.|.:.|:..|..|.: .....||
Zfish   252 AYLIRDWRHLILVVTSPCLVGIIAWWWIPESARWLLANGRVEEAQKYLINCAKMNGKYSYTKKLD 316

  Fly   336 VQLTMYANDLDQKSKQKHSYCQVWDGETKRSQLVYIHLIWGGAMVLYNIILLMIRNLGAQQVHVN 400
            :: .:....:.:.|.:.|||..:......|..::...:.|......|..|...|...|. .:::.
Zfish   317 IE-NLKKITIAEDSNKNHSYLDLVRTPKLRKIVLCSGIFWFAVAFTYYGISFNITGFGL-NIYLT 379

  Fly   401 TAAMGFAEMVGLFVGLYLIL--YTRRHWR-WAGNLMIIAGLSTYLIWLLPETERNSRRVGLELVF 462
            ....|..| |...||.||.|  ..||:.: |:   :||||....|..::| ||..:.|.|:.
Zfish   380 QFIYGVIE-VPAKVGTYLTLDRIGRRNGQAWS---LIIAGALIGLNSVIP-TEFAAVRTGIA--- 436

  Fly   463 WLILKIANSASIAVLTTCTSEIVSKEKRVVLMLSVISFSRVC-LLFCPFLSCLTVIHHLVPITIL 526
             :|.|..:.|:..:....|||:..    .||        |.| |.:..|::  .:...|.|:.||
Zfish   437 -VIGKGFSEAAFTIAFLYTSELYP----TVL--------RQCGLGYTSFIA--RIGGSLAPMVIL 486

  Fly   527 ATMGWIYGLALRRLNRYYWNTEQPQISQVPTPNTYRRQSAIILRRCSTVSSDCSAYSNELLSNFE 591
            ....|.||                      .|         ::...:.|.|.|..:.....:|.:
Zfish   487 FEDIWHYG----------------------PP---------VVFSATAVFSGCVVFLLPETTNVQ 520

  Fly   592 RNMAVSIADIWHINFHPSSEIEMEVE----QSGP 621
              :..:|.|:.......|:|.|.:||    .|||
Zfish   521 --LPENILDVEEGRHTLSTEAERDVELNEMNSGP 552

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4459	NP_650850.1	MFS_SLC22	139..540	CDD:340875	96/408 (24%)
slc22a7a	NP_001077330.1	MFS_SLC22A7_OAT2	109..514	CDD:341005	103/460 (22%)