Protein Alignment CG4459 and SLC22A23

DIOPT Version :9

• Sequence 1: NP_650850.1
• Gene: CG4459 / 42377
• FlyBaseID: FBgn0038753
• Length: 632
• Species: Drosophila melanogaster
• Sequence 2: XP_011513103.1
• Gene: SLC22A23 / 63027
• HGNCID: 21106
• Length: 710
• Species: Homo sapiens
• Alignment Length: 465
• Identity: 96/465 - (20%)
• Similarity: 176/465 - (37%)
• Gaps: 86/465 - (18%)

  Fly    26 GSFGRWQLRTILLIFLCKIPSAWFTAIIIYTAPYPWKGELVCHPADWNVSRSQTEHVDRNH--PL 88
            |..|.|          ..:|:..|.     |||:...|           :||.:...|...  ||
Human   147 GDMGNW----------TSLPTTPFA-----TAPWEAAG-----------NRSNSSGADGGDTPPL 185

  Fly    89 WQDARSTDRLFNVDVCNAYSNSLARGFVRSHGQEWNASQSKEPGGQSSLPCEHVEHRTDYKSLIS 153
            .......|...|.| |.|:...:..|.|::...:  ..|.:|.|   :||.:     ||.|....
Human   186 PSPPDKGDNASNCD-CRAWDYGIRAGLVQNVVSK--CCQQQETG---ALPWD-----TDTKRWRP 239

  Fly   154 Q--FDLICSRRVLVALTQSFHALGALIGGLMAYSALKKISPRRLMLLGMIGQIFCGNLTGL---V 213
            :  :||:|.....|.:.:....:|.:.|.|:.......:..|.::|..:|..:..|....|   |
Human   240 ELNWDLVCDNAWKVHIAKFSLLVGLIFGYLITGCIADWVGRRPVLLFSIIFILIFGLTVALSVNV 304

  Fly   214 DTYQLHIYFR--CLTSIFCALMYTSGQFILNDITSGKARIIVVTLSELFWSM-GLVLLPAISIYF 275
            ..:....:|.  ||..|...|      :.|........:..::|:...|.:| |..|:|.::...
Human   305 TMFSTLRFFEGFCLAGIILTL------YALRIELCPPGKRFMITMVASFVAMAGQFLMPGLAALC 363

  Fly   276 DNWSYLYVAISSSLIVLVWLHRWIADAPRWLLQHQRVEAALRQLLESATYNNRKVPLTLDVQLTM 340
            .:|..|...|....::::.......::.|||:..|:.|:|.|.:|. .|..||..|   :..:..
Human   364 RDWQVLQALIICPFLLMLLYWSIFPESLRWLMATQQFESAKRLILH-FTQKNRMNP---EGDIKG 424

  Fly   341 YANDLDQK-SKQKHSYCQVWDGETKRSQLVYIHLIWGGAMVLYNIILLMIRNLGAQQVH--VNTA 402
            ...:|::: |::....|.|        ::|....:|      .||::|.:.:|....:|  ...:
Human   425 VIPELEKELSRRPKKVCIV--------KVVGTRNLW------KNIVVLCVNSLTGYGIHHCFARS 475

  Fly   403 AMGFAEMVGLFVGLYLILYTRRHWRWAGNLMIIAGLSTYLIWLLPETERNSRRVGLELVFWLILK 467
            .||....|.|....|...||      ..::.:::.|:..::     .....||.|| |:|.::..
Human   476 MMGHEVKVPLLENFYADYYT------TASIALVSCLAMCVV-----VRFLGRRGGL-LLFMILTA 528

  Fly   468 IANSASIAVL 477
            :|:...:.:|
Human   529 LASLLQLGLL 538

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4459	NP_650850.1	2A0119	26..536	CDD:273328	96/465 (21%)
		MFS	164..540	CDD:119392	64/323 (20%)
SLC22A23	XP_011513103.1	2A0119	<243..652	CDD:273328	67/332 (20%)
		MFS	259..>388	CDD:119392	24/134 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165153270
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.930