DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG4459 and oatx

DIOPT Version :9

Sequence 1:	NP_650850.1	Gene:	CG4459 / 42377	FlyBaseID:	FBgn0038753	Length:	632	Species:	Drosophila melanogaster
Sequence 2:	XP_017208528.1	Gene:	oatx / 555218	ZFINID:	ZDB-GENE-070115-1	Length:	567	Species:	Danio rerio

Alignment Length:	572	Identity:	125/572 - (21%)
Similarity:	230/572 - (40%)	Gaps:	87/572 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    19 DVVEQVNGSFGRWQLRTILLIFLCKIPSAWFTAIIIYTAPYPWKGELVCHPADWNVSRSQTEHVD 83
            |::::| |.|||:|:   :.:.|..||                 |.|:   |..|:..:.|..|.
Zfish     5 DLLDEV-GGFGRFQM---IHVTLLSIP-----------------GLLM---ASQNLLNNFTAGVP 45

  Fly    84 RNHPLWQDARSTDRLFNVDVC-NAYSNSLARGFV------------RSHGQEWNASQSK-EPGGQ 134
            .:|         .|:.||... |..:.:|.|.|:            |....:|:....| ..|..
Zfish    46 EHH---------CRIPNVTTAMNDSTTTLLRAFIPLDSSLTLSKCSRYKDTQWHLITDKLSHGNA 101

  Fly   135 SSLPCEHVEHRTDY------KSLISQFDLICSRRVLVALTQSFHALGALIGGLMAYSALKKISPR 193
            :.|..|.......|      .|::|::||:|:.|.|..::|:.: :|.::.|.:.:..|.....|
Zfish   102 TELQTEGCADGWTYDKSEFISSIVSEWDLVCTLRPLKQMSQTIY-MGGVLTGAIIFGGLSDRFGR 165

  Fly   194 RLMLLGMIGQI-FCGNLTGLVDTYQLHIYFRCLTSIFCALMYTSGQFILNDIT------SGKARI 251
            :.:|:....|: ..|:.|.|..:|.::..||.||.     |..|| .|||.::      ..|.|.
Zfish   166 KALLIWSYFQLALLGSFTALAPSYVVYCIFRFLTG-----MSVSG-VILNAVSLKVEWIPTKTRT 224

  Fly   252 IVVTLSELFWSMGLVLLPAISIYFDNWSYLYVAISSSLIVLVWLHRWIADAPRWLLQHQRVEAAL 316
            :|.|||..|::.|.::|..::....:|..:.:|:.....:......|.:::.|||:.:.|.|.||
Zfish   225 LVGTLSSFFFTFGQMVLAGVAYSLRDWRKIQMAVCLPFFIFFMYSWWFSESARWLVLNGRSEEAL 289

  Fly   317 RQLLESATYNNRKVPLTLDVQLTMYANDLDQKSKQKHSYCQVWD---GETKRSQLVYIHLIWGGA 378
            : ||......|.|..:|..:.|....:.:.::.:...|...|:|   ..|.|...:.:.::|...
Zfish   290 K-LLHRVAKINGKPEMTEKITLEELESHMQKEVQSSKSIYTVFDLLRTPTMRKISMCLMVVWFST 353

  Fly   379 MVLYNIILLMIRNLGAQQVHVNTAAMGFAEMVGLFVGLYLILYTRRHWRWAGNLMIIAGLSTYLI 443
            ...|..:.:.::..|. .:::.....|..:.....|.|.::.:..|.......|::.|.:....|
Zfish   354 SFAYYGLAMDLQKFGV-NIYLMQVIFGAVDFPAKLVALLMLSFLGRRLTQGACLLVSASIIFANI 417

  Fly   444 WLLPETERNSRRVGLELVFWLILKIANSASIAVLTTCTSEIVSKEKRVVLMLSVISFSRVCLLFC 508
            : :||..:.:|     ....::.|...|||...:...|.|:.....|...|..|.:.||:..:..
Zfish   418 F-VPEDMQVTR-----TALAVLGKGFTSASFTCVYLFTGELYPTVIRQTGMGFVSTMSRIGSMAA 476

  Fly   509 PFLSCLTVIHHLVPITILATMGWIYGLALRRLNRYYWNTEQPQISQVPTPNT 560
            |.:..|..|...:|..:......|.||....|         |:...:|.|:|
Zfish   477 PAVLILDDILPALPSIVYGGSAVIAGLIAFLL---------PETLNIPLPDT 519

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4459	NP_650850.1	2A0119	26..536	CDD:273328	117/539 (22%)
CG4459	NP_650850.1	MFS	164..540	CDD:119392	83/385 (22%)
oatx	XP_017208528.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.910