DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG4459 and CG6006

DIOPT Version :9

Sequence 1:	NP_650850.1	Gene:	CG4459 / 42377	FlyBaseID:	FBgn0038753	Length:	632	Species:	Drosophila melanogaster
Sequence 2:	NP_001097812.1	Gene:	CG6006 / 41962	FlyBaseID:	FBgn0063649	Length:	603	Species:	Drosophila melanogaster

Alignment Length:	548	Identity:	121/548 - (22%)
Similarity:	236/548 - (43%)	Gaps:	69/548 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 GSIPRKSSPELDVVEQVNGSFGRWQLRTILLIFLCKIPSAWFTAIIIYTAPYPWKGELVCHPADW 72
            |..|.....|.||:..:.|.:|:|||...:|:.|.::|:.:..:..||.|         .:...|
  Fly    72 GLDPADDEDETDVIGDLMGHYGKWQLLMTVLLSLFQVPNTFHISSSIYQA---------ANKDFW 127

  Fly    73 NVSRSQTEHVDRNHPL--WQDARSTDRLFNVDVCNAYSNSLARGFVRSHGQEWNASQSKEPGGQS 135
            ....:|.:|:    |:  |::...     :||.|.           |..|.:|:     :...::
  Fly   128 CQRPAQLQHM----PVATWRNLSG-----SVDNCR-----------RWEGIDWS-----QVSNET 167

  Fly   136 SLP---------------CEHVEHRTD---YKSLISQFDLICSRRVLVALTQSFHALGALIGGLM 182
            :||               ||..|:.|:   ..:..||:||:|.:..|..:.:.|..||...||::
  Fly   168 TLPSDWKTPAEMDKKLVACEKWEYETNDNVGNTWTSQWDLVCEKEHLKNVAEMFFLLGVATGGII 232

  Fly   183 AYSALKKISPRRLMLLGMIGQIFCGNLTGLVDTYQLHIYFRCLTSIFCALMYTSGQFILNDITSG 247
            :.....|...:.::.:..:.|...|....:..:::|::..|.|..:....:..||..:..:...|
  Fly   233 SGYLSDKFGRKTMLFISAVLQTIFGLWLYICSSFELYLTLRALLGLVSVSVTYSGLILAIEYVDG 297

  Fly   248 KARIIVVTLSELFWSMGLVLLPAISIYFDNWSYLYVAISSSLIVLVWLHRWIADAPRWLLQHQRV 312
            |.|.|....:.....:..:::..::....::..|.:.|....|.|.:|...:.::|||||...|:
  Fly   298 KWRTIAGMYNLFPLPISYMIISGLAYLTQDYQRLQLCIGIPGIFLCFLWFVVPESPRWLLVKGRI 362

  Fly   313 EAALRQLLESATYNNRKVPLTLDVQLTMYANDLDQKSKQKHSYCQVWDGETKRSQLVYIHLIWGG 377
            :...|.:..:|.:|.|::|  .|.|||   ....:.|.|..:|  ::.....|...:....||..
  Fly   363 DEVRRIIEAAAKFNGRQLP--ADYQLT---PPTQESSTQDVTY--LFRSSYLRRISICFFCIWFT 420

  Fly   378 AMVLYNIILLMIRNLGAQQVHVNTAAMGFAEMVGLFVGLYLILYTRRHWRWAGNLMIIAGLSTYL 442
            ..::|..|:|.:.:.|. .|::|:|..|..|:..:.|.:|:|....:.|.:...| |.||::...
  Fly   421 MNLVYYGIILNMSSFGG-NVYLNSALAGLVEIPAIAVAMYIITKVGKKWLFCATL-ICAGVACCC 483

  Fly   443 IWLLPETERNSRRVGLELVFWLILKIANSASIAVLTTCTSEIVSKEKRVVLMLSVISFSRVCLLF 507
            ..:   ||.::..:.|::.|.::.|...||...::...|:|:.....|.|.:.:....:.:.|:.
  Fly   484 AAI---TEGHADLLWLKITFLMMGKFTISAGNTIMPVYTAELYPTPIRNVGVGACNVAAGLALIL 545

  Fly   508 CPFLSCLTVIHHLVPITILATMGW-IYG 534
            .|:||.|..|...:.:|:|.  .| |:|
  Fly   546 TPYLSLLNKIEGHLLMTLLT--AWSIFG 571

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4459	NP_650850.1	2A0119	26..536	CDD:273328	116/530 (22%)
CG4459	NP_650850.1	MFS	164..540	CDD:119392	83/372 (22%)
CG6006	NP_001097812.1	2A0119	90..581	CDD:273328	116/530 (22%)
CG6006	NP_001097812.1	MFS	222..579	CDD:119392	81/364 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E33208_3BMR2
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D704438at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24064
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.920