Protein Alignment CG4459 and SLC22A

DIOPT Version :9

• Sequence 1: NP_650850.1
• Gene: CG4459 / 42377
• FlyBaseID: FBgn0038753
• Length: 632
• Species: Drosophila melanogaster
• Sequence 2: NP_649370.1
• Gene: SLC22A / 40437
• FlyBaseID: FBgn0037140
• Length: 568
• Species: Drosophila melanogaster
• Alignment Length: 606
• Identity: 140/606 - (23%)
• Similarity: 246/606 - (40%)
• Gaps: 113/606 - (18%)

  Fly    11 PRKSSPE--LDVVEQVNGSFGRWQLRTILLIFLCKIPSAWFTAIIIYTAPYPWKGELVCHPADWN 73
            |.|.|.:  ||.:.:..|.|||:||...|||.|..:..|.|:...::||      ..|.|
  Fly    18 PAKDSEDVTLDAILKHLGQFGRFQLIIFLLICLPMMFHAMFSVTYVFTA------ATVTH----- 71

  Fly    74 VSRSQTEHVD-------RNHPLWQDARSTDRLFNVDVCNAYSNSLARGFVRSHGQEWNAS----- 126
              |...|..|       ..|..|...::..   ::|.||.|:|        |...:||.|
  Fly    72 --RCSVEECDLPGSNYYEPHTNWSIPKNGK---DLDSCNRYTN--------SELPQWNHSVDICS 123

  Fly   127 -----QSKEPGGQSSLPCEHVE--HRTDYKSLISQFDLICSRRVLVALTQSFHALGAL----IGG 180
                 ::||       .|.|.|  .|.|..::.:.|.:.|.....:::..:.:.||..    |||
  Fly   124 ADHFTKNKE-------ACAHNEFVFRDDEVTISNDFGIFCDDEWKLSMVGTINNLGQFFGIPIGG 181

  Fly   181 LMAYSALKKISPRRLMLLGMIGQIFCGNLTGLVDTYQLHIYFRCLTSIFCALMYTSGQFILNDIT 245
            .:|....:..|   :.|.|::|.:. |.:.....:|...:.|..|.::..:.:|::...|..::.
  Fly   182 FVADRYGRSFS---IALGGILGAVL-GVIRSFSPSYGWFLVFEFLDNMTSSTLYSTCFVIGIELV 242

  Fly   246 SGKARIIVVTLSELFWSMGLVLLPAISIYFDNWSYLY-VAISSSLIVLVWLHRWI-ADAPRWLLQ 308
            ..|.|::..::..:|:::|.|||...:..|.:|..|. :....|||:|.:.  || .::.||||.
  Fly   243 GPKRRVLACSVITVFYAVGEVLLAMSAKAFHDWRILLRITYGPSLILLAYF--WILPESVRWLLS 305

  Fly   309 HQRVEAALRQLLESATYNNRKVPLTLDVQLTMYAND-LDQKSKQKHSYCQVWDGETKRSQLVYIH 372
            ..:.|.|...|..:|..|.|::|.::..:|.:...| |.|.|:.:....:.:  :..:.::....
  Fly   306 QGKEERAKNILRRAAHVNKRELPESVLDKLVLANRDKLQQSSESRFPIREAF--KNFKWRIANCS 368

  Fly   373 LIWGGAMVLY-----NIILLMIRNLGAQQVHVNTAAMGFAEMVGLFVGLYLILYTRRHWRWAGNL 432
            |.|...:::|     |::||      ....:.|.|.:...|:.|.|:.|.::....|.:...| |
  Fly   369 LCWIVHVLVYYGLSLNVVLL------DGDKYNNFAYIALVEIPGFFMPLLIMDRFGRRYSLCG-L 426

  Fly   433 MIIAGLSTYLIWLLPETERNSRRVG----------LELVFWLILKIANSASIAVLTTCTSEIVSK 487
            |:.:||..               :|          |:||.:|:.|:..:||..||....|||...
  Fly   427 MLASGLCC---------------IGTIFTGADQPVLQLVLFLVGKLTITASFQVLYFFASEIYPT 476

  Fly   488 EKRVVLMLSVISFSRVCLLFCPFLSCLTVIHHLVPITILATMGWIYGLALRRLNRYYWNTEQPQI 552
            ..|..|:.......|...:..|....|...:...|..:.|....:.||    |..::     |:.
  Fly   477 NLRNSLLSFCSMMGRFGSMLAPQTPLLAKYYANAPAMLFAGAAIVSGL----LTLFF-----PET 532

  Fly   553 SQVPTPNTYRRQSAIILRRCS 573
            :.|..|.|.:...||.:::.|
  Fly   533 TNVVLPTTVQEADAIGVKKQS 553

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4459	NP_650850.1	2A0119	26..536	CDD:273328	126/550 (23%)
		MFS	164..540	CDD:119392	88/397 (22%)
SLC22A	NP_649370.1	2A0119	35..540	CDD:273328	131/574 (23%)
		MFS	146..530	CDD:119392	91/422 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45458328
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24064
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.940