Protein Alignment CG4459 and Slc22a14

DIOPT Version :9

• Sequence 1: NP_650850.1
• Gene: CG4459 / 42377
• FlyBaseID: FBgn0038753
• Length: 632
• Species: Drosophila melanogaster
• Sequence 2: NP_001032838.1
• Gene: Slc22a14 / 382113
• MGIID: 2685974
• Length: 629
• Species: Mus musculus
• Alignment Length: 578
• Identity: 119/578 - (20%)
• Similarity: 224/578 - (38%)
• Gaps: 142/578 - (24%)

  Fly    12 RKSSPELDVVEQVNGSFGRWQLRTILLIFLCKIPSAW--FTAIIIYTAPYPWKGELVCHPADW-- 72
            |:......|::.: |.||.:|.|.::|.|:..|.|.:  |:...:.||..|:     |: ..|
Mouse    46 RRDDKFASVMDAI-GEFGTFQWRLVVLTFIPSILSTFFIFSHHFLLTAQRPY-----CN-TSWIL 103

  Fly    73 NVSRSQTEHVDRNHPL------------------WQDARSTDRLFNVDVCNAYSNSLARGFVRSH 119
            .|..:.||....|..|                  |    ..|.:.:..:  .|:.:...|::
Mouse   104 EVGPNLTEDEQLNLTLPRAPNGSFLTCLMYIPVPW----DLDSIIHFGL--NYTETCKFGWI--- 159

  Fly   120 GQEWNASQSKEPGGQSSLPCEHVEHRTDYKSLISQFDLICSRR------VLVALTQSFHALGALI 178
                             .|..|.      :|||::|||:|...      :.|.|:      |.|.
Mouse   160 -----------------YPFAHT------RSLINEFDLVCGNEPNKENGLTVFLS------GVLT 195

  Fly   179 GGLMAYSALKKISPRRLMLLGMIGQIFCGNLTGLVDTYQLHIYFR---CLTSIFCALMYTSGQFI 240
            |.|:......|:....::||.::|.:..|..|..|.::..:::||   ...|:..|:...|   :
Mouse   196 GSLLFGFLSDKLGRYPIILLSLLGFLIFGFGTAFVSSFYQYLFFRFFVAQASVGYAICSVS---L 257

  Fly   241 LNDITSGKARIIVVTLSELFWSMGLVLLPAISIYFDNWSYLYVAISS---SLIVLVWLHRWIADA 302
            :.:...|:.|...|.|...|.::|::||..::....:|..|.:....   .||..:|:.|   ::
Mouse   258 VMEWLVGEHRAQAVILQHSFLTIGVILLTGLAYKVVHWRLLCLLGGMPMFPLICNIWVLR---ES 319

  Fly   303 PRWLLQHQRVEAALRQLLESATYNNRKVPLTLDVQLTMYANDLDQKSKQKHSYCQVWDGETKR-- 365
            ||||:...:||.|.:.|..:|..|.:.:||.|       .|:| |.|.:|.:...:.|..|.:
Mouse   320 PRWLMVRGKVEEAKKVLCYAAEVNKKTIPLNL-------LNEL-QISGKKVAKASILDFCTNQHL 376

  Fly   366 -SQLVYIHLIWGGAMVLYNIILLMIRNLGAQQVHVNTAAMGFAEMVGLFVG-------LYLILYT 422
             ..::.|..:|.....:...:.|.:.:.|..        :.|.:||...|.       :.|:.|.
Mouse   377 FKVVLAIGCVWFTVSYISFTLNLKMNDFGLD--------VYFVQMVRSIVAVPARLCCIILLEYF 433

  Fly   423 RRHWRWAGNLMIIAGLSTYLIWLLPETERNSRRVGLELVFWLIL-KIANSASIAVLTTCTSEIVS 486
            .|.|.....|.::..:..:|:: ||:..:::      ::..|:| :.:.:.::::....|:|::.
Mouse   434 GRKWALNLTLFLVTSMCLFLLF-LPQEPKST------IILTLMLAEFSMAGTLSIFFIYTAELLP 491

  Fly   487 KEKRVV------------LMLSVISFSRV--------CLLFCPFLSCLTVIHHLVPIT 524
            ...|..            .:.||..|.:.        |.|.|....|.:   .|||.|
Mouse   492 TVLRSTGLGMVSLAWVAGAISSVAIFKQTKTQLPIFFCCLCCVLALCFS---SLVPET 546

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4459	NP_650850.1	2A0119	26..536	CDD:273328	117/564 (21%)
		MFS	164..540	CDD:119392	84/398 (21%)
Slc22a14	NP_001032838.1	2A0119	59..553	CDD:273328	117/564 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167843683
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D704438at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.850