DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG4459 and Balat

DIOPT Version :9

Sequence 1:	NP_650850.1	Gene:	CG4459 / 42377	FlyBaseID:	FBgn0038753	Length:	632	Species:	Drosophila melanogaster
Sequence 2:	NP_610823.1	Gene:	Balat / 36417	FlyBaseID:	FBgn0033778	Length:	604	Species:	Drosophila melanogaster

Alignment Length:	609	Identity:	126/609 - (20%)
Similarity:	234/609 - (38%)	Gaps:	103/609 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    17 ELDVVEQVNGSFGRWQLRTILLIFL-CKIPSAW--FTAIIIYTAPY---------PWKGELV--- 66
            :.|.|.:..||||.:|...|..:.| ..:|.|:  ::.:.|...|.         ||..:.|
  Fly     2 DFDEVLREVGSFGLYQKVIICSVLLPAALPCAFHAYSQLFIAATPQHFCRVPELEPWTQDYVQLV 66

  Fly    67 ---CHPADWNVSRSQTEHVDRNHPLWQDARSTDRLFNVDVCNAYSNSLARGFVRSHGQEWNASQS 128
               ..|.:.|.:.::.....||:              .|:............:|...::....|
  Fly    67 KNLSIPRNRNGAYAECSMYSRNY--------------TDIVRYLEYRPPPDLLRQQAEDLLKLQ- 116

  Fly   129 KEPGGQSSLPCEHVEH--RTDYKS-LISQFDLICSRRVLVALTQSFHALGALIGGLMAYSALKKI 190
              |.....:||:|..|  ::.|.| ::.:::|:|.|..||.|......:|.|:|..: :..|..:
  Fly   117 --PDTTQVVPCQHGWHYDKSIYSSTVVQEWNLVCDRSFLVTLALVVFGVGGLLGNYV-FGYLVDL 178

  Fly   191 SPRR--------LMLLGMIGQIFCGNLTGLVDTYQLHIYFRCLTSIFCALMYTSGQFILNDITSG 247
            ..||        |.::......|..|       |...:..|.:..:....:..|...:..::...
  Fly   179 WGRRPSFYAYLLLEIIACAASAFAWN-------YYTWLGLRFVVGLTVPAILASPYVLAIELVGP 236

  Fly   248 KARIIVVTLSELFWSMGLVLLPAISIYFDNWSYLYVAISSSLIVLVWLHRWIADAPRWLLQHQRV 312
            :.|:....:|.:.:|:|||:|..:.....:|..|.:|:|..|::|......:.::||||:...:.
  Fly   237 ERRVFCTIVSNIAYSLGLVVLAGVIYIVRDWRELSLAVSMPLLMLFSCFFVLPESPRWLMAVGKT 301

  Fly   313 EAALRQLLESATYN----NRKVPLTLDVQLTMYANDLDQKSKQKHSY--CQVWDGETKRSQLVYI 371
            ..|::.|...|..|    ||.....|..:|.: ....:.||.....|  ..::.|...|.:.:.|
  Fly   302 RRAIKILKVMARVNGVRVNRDFVERLQRKLVI-TRAAETKSSMTTHYGILDLFRGPNMRRKTLII 365

  Fly   372 HLIWGGAMVLYNIILLMIRNLGAQQVHVNTAAMGFAEMVGLFVGLYLILYTRRHW---RWAGNL- 432
            .|||.....:|..:......||..::. |....|..|:     ..||:|:....:   ||...:
  Fly   366 TLIWFANTSVYVGLSYYAPALGGDEIW-NFFLAGAVEL-----PTYLLLWPGLSYFGRRWILFIS 424

  Fly   433 MIIAGLSTYLIWLLPETERNSRRVGLELVFWLILKIANSASIAVLTTCTSEIVSKEKRVVLMLSV 497
            |::.|::....:|.|:         :.|:.:.:.|:..|:|..||....||:.....|.:.|
  Fly   425 MLVGGVACVATFLYPD---------ITLLLYCVGKMGISSSFVVLPLMASELYPTVVRGLGM--- 477

  Fly   498 ISFSRVCLLFCPFLSCLTVIHHL------VPITILATMGWIYGLALRRLNRYYWNTEQPQISQVP 556
             |||.|..:..|.:  :.:|:|:      :|:.::..:..:.|.|...|         |:.....
  Fly   478 -SFSSVISMVGPIV--IPMINHMGQQMLVLPLIVMGALLILGGFASLLL---------PETRNRN 530

  Fly   557 TPNTYRRQSAIILR--RCSTVSSD 578
            .|.|.....|:.|.  .|..|.|:
  Fly   531 LPQTLEEGEAVPLSFLLCCCVESE 554

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4459	NP_650850.1	2A0119	26..536	CDD:273328	114/554 (21%)
CG4459	NP_650850.1	MFS	164..540	CDD:119392	84/399 (21%)
Balat	NP_610823.1	MFS_SLC22	128..524	CDD:340875	91/434 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45458415
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24064
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.940