Protein Alignment CG4459 and Slc22a14

DIOPT Version :9

• Sequence 1: NP_650850.1
• Gene: CG4459 / 42377
• FlyBaseID: FBgn0038753
• Length: 632
• Species: Drosophila melanogaster
• Sequence 2: NP_001101663.2
• Gene: Slc22a14 / 316061
• RGDID: 1306470
• Length: 630
• Species: Rattus norvegicus
• Alignment Length: 612
• Identity: 138/612 - (22%)
• Similarity: 238/612 - (38%)
• Gaps: 120/612 - (19%)

  Fly    26 GSFGRWQLRTILLIFLCKIPSAWF--TAIIIYTAPYPWKGELVCHPADW--NVSRSQTEHVDRNH 86
            |.||.:|.|.:.|.|:..|.|.:|  :...:.||..|:     |: ..|  .|..:.||
  Rat    59 GEFGTFQWRLVALTFIPSILSTFFLLSHHFLLTAQRPY-----CN-TSWILQVGPNLTE------ 111

  Fly    87 PLWQDARSTDRLFNVDVCNAYSNSLARGFVRSHGQEWNASQSKEPGGQSSLPCEH--VEHRTDYK 149
                     |...|:.|..|.:.|.....:.. ...|:.......|...:..|:|  :......:
  Rat   112 ---------DEQLNLTVPRAPNGSFLTCLMYI-PVPWDLDSIVHFGLNYTETCKHGWIYPFAHTR 166

  Fly   150 SLISQFDLICSRRVLVALTQSFHALGALIGGLMAYSALKKISPRRLMLLGMIGQIFCGNLTGLVD 214
            ||.::|||:|.........|:....|.|.|.|:......|:....::||.::|.:..|..|..|:
  Rat   167 SLTNEFDLVCGNEPHEENGQTVFLSGILTGSLLFGFLSDKLGRYPIILLSLLGILIFGFGTAFVN 231

  Fly   215 TYQLHIYFR---CLTSIFCALMYTSGQFILNDITSGKARIIVVTLSELFWSMGLVLLPAISIYFD 276
            ::..:::||   ...|:..|:...|   ::.:...|:.|...:.|...|:::|::||...:...:
  Rat   232 SFYQYLFFRFFVAQASVGYAICSVS---LVMEWLVGEHRAQAIILQHCFFTIGVILLTGFAYKIN 293

  Fly   277 NWSYLYV---AISSSLIVLVWLHRWIADAPRWLLQHQRVEAALRQLLESATYNNRKVPLTLDVQL 338
            :|..|::   .....||..:|:   :.::||||:...:||.|.:.|..:|..|.:.:||.|
  Rat   294 HWRLLFLLGGVPMFPLICNIWV---LQESPRWLMVKGKVEEAKKVLCYAAEVNKKTIPLNL---- 351

  Fly   339 TMYANDLDQKSKQKHSYCQVWDGETKRSQLVYIHLIWGGAMVLYNIILLMIRNLGAQQVHVNTAA 403
               .|:|....|:  :...:.|..|.:.              |:.::|                |
  Rat   352 ---LNELQLPGKK--AKASILDFYTNQH--------------LFKVVL----------------A 381

  Fly   404 MGFAEMVGLFVGLYLILYTRRHWRWAGNLMIIAGLSTYLIWLLP-ETERNSRRVGLELVFWLILK 467
            ||.......:|.|.|.|..:..           ||..|.|.::| .|...:|...:.|:.:...|
  Rat   382 MGCVWFTVSYVSLTLSLKMKDF-----------GLDIYFIQVVPCITAVPARLCCILLLEYFGRK 435

  Fly   468 IANSASIAVLT-TCTSEIVSKEK---RVVLMLSVISFS---RVCLLFCPFLSCLTVIHH---LVP 522
            .:.:.:::::| ||.|.:...|:   ..:|||.:..||   .|.:.|......|..|..   |..
  Rat   436 WSLNLTLSLVTFTCLSLLFVPEELKSTTILMLVLGEFSMAGTVSIFFIYTAELLPTILRSTGLGM 500

  Fly   523 ITILATMGWIYGLALRRLNRYYWNTEQPQI-------------SQVP-TPNTYRRQSAIILRRCS 573
            ::|..|.|.|..||:.:..:    |:.|..             |.|| |.|...|.|.....|.|
  Rat   501 VSIAWTAGAISSLAIFKQTK----TQLPIFFCCLCCILALCFSSLVPETGNQPLRDSIEYCSRDS 561

  Fly   574 TVSSDCSAYSNELLSNFERNMAVSIAD 600
            ....|.|..|:::|. .|.:|....||
  Rat   562 LEHKDKSKDSSKVLM-AEESMCDVAAD 587

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4459	NP_650850.1	2A0119	26..536	CDD:273328	117/532 (22%)
		MFS	164..540	CDD:119392	86/392 (22%)
Slc22a14	NP_001101663.2	MFS	147..527	CDD:421695	97/439 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D704438at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010