Protein Alignment CG4459 and Slc22a12

DIOPT Version :9

• Sequence 1: NP_650850.1
• Gene: CG4459 / 42377
• FlyBaseID: FBgn0038753
• Length: 632
• Species: Drosophila melanogaster
• Sequence 2: NP_033229.3
• Gene: Slc22a12 / 20521
• MGIID: 1195269
• Length: 553
• Species: Mus musculus
• Alignment Length: 592
• Identity: 125/592 - (21%)
• Similarity: 231/592 - (39%)
• Gaps: 116/592 - (19%)

  Fly    16 PELDVVEQVNGSFGRWQL-RTILLIFLCKIPSAWFTA---IIIYTAPYPWKGELVCHPADWNVSR 76
            |||  :::| |..||:|| :|:.|:    .|..|.|.   :..::|..|       |...|
Mouse     4 PEL--LDRV-GGLGRFQLFQTVALV----TPILWVTTQNMLENFSAAVP-------HHRCW---- 50

  Fly    77 SQTEHVDRNHPLWQDARSTDRL---FNVDVCNAYS-----NSLARGFVRSHGQEWNASQSKEP-- 131
                     .||..::.|...:   ...||..|.|     :......:|....:|..::|...
Mouse    51 ---------VPLLDNSTSQASIPGDLGPDVLLAVSIPPGPDQQPHQCLRFRQPQWQLTESNATAT 106

  Fly   132 --GGQSSLPCEH---VEHRTDYKSLISQFDLICSRRVLVALTQSFHALGALIGGLMAYSALKKIS 191
              ...::.|||.   .:|.|...::::.:||:|:.:.|..:.||....|.|:|..:...|..:..
Mouse   107 NWSDAATEPCEDGWVYDHSTFRSTIVTTWDLVCNSQALRPMAQSIFLAGILVGAAVCGHASDRFG 171

  Fly   192 PRRLMLLGMIGQIFCGNLTGLVDTYQLHIYFRCLTSIFCALMYTSGQFILNDITSGKARIIVVTL 256
            .||::....:.....|.....:.|:.|:..||.|.:...|.:..:...:|.:.||.:...:|:||
Mouse   172 RRRVLTWSYLLVSVSGTAAAFMPTFPLYCLFRFLLASAVAGVMMNTASLLMEWTSAQGSPLVMTL 236

  Fly   257 SELFWSMGLVLLPAISIYFDNWSYLYVAISSSLIVLVWLHRWIADAPRWLLQHQRVEAALRQLLE 321
            :.|.:|.|.||..:::....:|..|.:|:|:...:......|:.::.|||:...:::..|::|..
Mouse   237 NALGFSFGQVLTGSVAYGVRSWRMLQLAVSAPFFLFFVYSWWLPESARWLITVGKLDQGLQELQR 301

  Fly   322 SATYNNRKV---PLTLDVQLTMYANDLDQKSKQKHSYCQVWDGETKRSQLVYIHLIW-------- 375
            .|..|.||.   .||::| |.....:...:.|...|...:......|.:.:...|.|
Mouse   302 VAAVNRRKAEGDTLTMEV-LRSAMEEEPSRDKAGASLGTLLHTPGLRHRTIISMLCWFAFGFTFY 365

  Fly   376 GGAMVLY----NIILLMIRNLGAQQVHVNTAAMGFAEMVGLFVGLYLILYTRRHWRWAG-NLMII 435
            |.|:.|.    ||.||... :|.....|.|.:              |:|.:|...|... :.:::
Mouse   366 GLALDLQALGSNIFLLQAL-IGIVDFPVKTGS--------------LLLISRLGRRLCQVSFLVL 415

  Fly   436 AGLSTYLIWLLPETERNSRRVGLELVFWLILKIANSASIAVL--------TTCTSEIVSKEKRVV 492
            .||......|:|.        |:.::         .:::|||        .||.:...|:....|
Mouse   416 PGLCILSNILVPH--------GMGVL---------RSALAVLGLGCLGGAFTCITIFSSELFPTV 463

  Fly   493 LMLSVISFSRVC----LLFCPFLSCLTVIHHLVPITILATMGWIYGLALRRLNRYYWNTEQPQIS 553
            :.::.:...:|.    .:..|.:..|.|....:|:.:...:..:.|||...|         |:..
Mouse   464 IRMTAVGLCQVAARGGAMLGPLVRLLGVYGSWMPLLVYGVVPVLSGLAALLL---------PETK 519

  Fly   554 QVPTPNT 560
            .:|.|:|
Mouse   520 NLPLPDT 526

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4459	NP_650850.1	2A0119	26..536	CDD:273328	114/556 (21%)
		MFS	164..540	CDD:119392	84/403 (21%)
Slc22a12	NP_033229.3	2A0119	11..526	CDD:273328	120/580 (21%)
		MFS	147..516	CDD:119392	84/410 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167843309
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.930