Protein Alignment CG4459 and Slc22a8

DIOPT Version :9

• Sequence 1: NP_650850.1
• Gene: CG4459 / 42377
• FlyBaseID: FBgn0038753
• Length: 632
• Species: Drosophila melanogaster
• Sequence 2: NP_001158106.1
• Gene: Slc22a8 / 19879
• MGIID: 1336187
• Length: 537
• Species: Mus musculus
• Alignment Length: 584
• Identity: 120/584 - (20%)
• Similarity: 215/584 - (36%)
• Gaps: 127/584 - (21%)

  Fly    19 DVVEQVNGSFGRWQLRTILLIFLCKIPSAWFTAIIIYTAPYPWKGELVCHP------ADWNVSRS 77
            :::::| ||.|.:|...:.|:.|..:..|....:.|:||..|   :..|.|      ..|.:
Mouse     5 EILDRV-GSMGPFQYLHVTLLALPILGIANHNLLQIFTATTP---DHHCRPPPNASLEPWVL--- 62

  Fly    78 QTEHVDRNHPLWQDARSTDRLFNVDVCNAYSNSLARGFVRSHGQEWNASQSKEPGGQSSLPCEHV 142
                     ||..:.:....|..|.:.||...:..:|........|..:.:::
Mouse    63 ---------PLGPNGKPEKCLRFVHLPNASLPNDTQGATEPCLDGWIYNSTRD------------ 106

  Fly   143 EHRTDYKSLISQFDLICSRRVLVALTQSFHALGALIGG----------------------LMAYS 185
                   ::::::||:|....|..:.||....|.|:||                      |.|..
Mouse   107 -------TIVTEWDLVCGSNKLKEMAQSVFMAGILVGGPVFGELSDRFGRKPILTWSYLLLAASG 164

  Fly   186 ALKKISPRRLMLLGMIGQIFCG-NLTGL-VDTYQLHIYF-----RCLTSIFCALMYTSGQFILND 243
            :....||.  :.:.||.:..|| :::|: :.|..|::.:     |.::|......||.||||
Mouse   165 SSAAFSPS--LTVYMIFRFLCGCSISGISLSTIILNVEWVPTSTRAISSTTIGYCYTIGQFI--- 224

  Fly   244 ITSGKARIIVVTLSELFWSMGLVLLPAISIYFDNWSYLYVAISSSLIVLVWLHRWIADAPRWLLQ 308
                                    ||.::.....|.:|.:::|::..:...|..|:.::.|||:.
Mouse   225 ------------------------LPGLAYAVPQWRWLQLSVSAAFFIFSLLSWWVPESIRWLVL 265

  Fly   309 HQRVEAALRQLLESATYNNRK---VPLTLDVQLTMYANDLDQKSKQKHSYCQVWDGETKRSQLVY 370
            ..:...||:.|...||:|.:|   ..||::........|: ..:|.|:....::.....|.....
Mouse   266 SGKFSKALKTLQRVATFNGKKEEGEKLTVEELKFNLQKDI-TSAKVKYGLSDLFRVSILRRVTFC 329

  Fly   371 IHLIWGGAMVLYNIILLMIRNLGAQQVHVNTAAMGFAEMVGLFVGLYLILYTRRHWRWAGNLMII 435
            :.|.|......|..:.:.:...|. .:::.....|..::...|:.:..|.|..|... .|.|:|:
Mouse   330 LSLAWFATGFAYYSLAMGVEEFGV-NIYILQIIFGGVDIPAKFITILSISYLGRRIT-QGFLLIL 392

  Fly   436 AGLSTYLIWLLPETERNSRRVGLELVFWLILKIANSASIAVLTTCTSEIVSKEKRVVLMLSVISF 500
            ||:: .|..:...:|....|..| .||.   |...|.|.:.|...|||:.....|...|.....:
Mouse   393 AGVA-ILALIFVSSEMQLLRTAL-AVFG---KGCLSGSFSCLFLYTSELYPTVLRQTGMGISNIW 452

  Fly   501 SRVCLLFCPFLSCLTVIHHLVPITILATMGWIYGLA----LRRLNRYYWNTEQPQISQVPTPNT 560
            :||..:..|.:.....:...:|..|..||..:.|.|    |..|||             |.|.|
Mouse   453 ARVGSMIAPLVKITGELQPFIPNVIFGTMTLLGGSAAFFLLETLNR-------------PLPET 503

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4459	NP_650850.1	2A0119	26..536	CDD:273328	111/547 (20%)
		MFS	164..540	CDD:119392	88/411 (21%)
Slc22a8	NP_001158106.1	2A0119	11..503	CDD:273328	118/575 (21%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	513..537

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167843659
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.840