Protein Alignment CG4459 and Slc22a6

DIOPT Version :10

• Sequence 1: NP_650850.1
• Gene: CG4459 / 42377
• FlyBaseID: FBgn0038753
• Length: 632
• Species: Drosophila melanogaster
• Sequence 2: NP_032792.2
• Gene: Slc22a6 / 18399
• MGIID: 892001
• Length: 545
• Species: Mus musculus
• Alignment Length: 534
• Identity: 108/534 - (20%)
• Similarity: 211/534 - (39%)
• Gaps: 74/534 - (13%)

  Fly    19 DVVEQVNGSFGRWQLRTILLIFLCKIPSAWFTAIIIYTAPYPWKGELVCH----PADWNVSRSQT 79
            |:::|| |..||:||..:.::....:..|....:..:||..|      .|    ||:.|:|:
Mouse     5 DLLKQV-GGVGRFQLIQVTMVVAPLLLMASHNTLQNFTAAIP------AHHCRPPANANLSK--- 59

  Fly    80 EHVDRNHPLWQDARSTDRLFNVDVCNAYSNSLARGFVRSHGQEWNASQSKEPGGQSSLPCEHVEH 144
               |.....|.......|          ..|..|.....:|.|.|.:...||    .|.....::
Mouse    60 ---DGGLEAWLPLDKQGR----------PESCLRFPFPHNGTEANGTGVTEP----CLDGWVYDN 107

  Fly   145 RTDYKSLISQFDLICSRRVLVALTQSFHALGALIGGLMAYSALKKISPRRLMLLGMIGQIFCGNL 209
            .|...:::::::|:||.|....|.||...:|.|:|.:|......::..|::::|..:.....|..
Mouse   108 STFPSTIVTEWNLVCSHRAFRQLAQSLFMVGVLLGAMMFGYLADRLGRRKVLILNYLQTAVSGTC 172

  Fly   210 TGLVDTYQLHIYFRCLTSIFCALMYTSGQFILNDITSG------KARIIVVTLSELFWSMGLVLL 268
            ......|.::..||.|:.:..|      ...:|.:|..      ..|..|.||....:|:|..||
Mouse   173 AAYAPNYTVYCIFRLLSGMSLA------SIAINCMTLNMEWMPIHTRAYVGTLIGYVYSLGQFLL 231

  Fly   269 PAISIYFDNWSYLYVAISSSLIVLVWLHRW-IADAPRWLLQHQRVEAALRQLLESATYNNRK--- 329
            ..|:....:|.:|.:|:|....| .:::.| ..::.||.....|::..||.|...|..|.::
Mouse   232 AGIAYAVPHWRHLQLAVSVPFFV-AFIYSWFFIESARWYSSSGRLDLTLRALQRVARINGKQEEG 295

  Fly   330 VPLTLDVQLTMYANDLDQKSKQKHSYCQVWDGETKRSQLVYIHLIWGGAMVLYNIILLMIRNLGA 394
            ..|:::|..|....:| ..:|.:.|..::....|.|...:.:.::|......|..:::.::..|.
Mouse   296 AKLSIEVLQTSLQKEL-TLNKGQASAMELLRCPTLRRLFLCLSMLWFATSFAYYGLVMDLQGFGV 359

  Fly   395 QQVHVNTAAMGFAEMVGLFVGLYLILYT--RRHWRWAGNLMIIAGLSTYLIWLLPETE---RNSR 454
             .:::.....|..::...|| .:|::.:  ||..:.|.  :::||:...:..::|...   |.|
Mouse   360 -SMYLIQVIFGAVDLPAKFV-CFLVINSMGRRPAQLAS--LLLAGICILVNGIIPRGHTIIRTS- 419

  Fly   455 RVGLELVFWLILKIANSASIAVLTTC----TSEIVSKEKRVVLMLSVISFSRVCLLFCPFLSCLT 515
                       |.:.....:|....|    |.|:.....|...:....:.:||..:..|.:|...
Mouse   420 -----------LAVLGKGCLASSFNCIFLYTGELYPTMIRQTGLGMGSTMARVGSIVSPLISMTA 473

  Fly   516 VIHHLVPITILATM 529
            ..:..:|:.|...:
Mouse   474 EFYPSIPLFIFGAV 487

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4459	NP_650850.1	MFS_SLC22	139..540	CDD:340875	80/410 (20%)
Slc22a6	NP_032792.2	2A0119	11..509	CDD:273328	105/527 (20%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	515..545