Protein Alignment CG4459 and lelo-2

DIOPT Version :10

• Sequence 1: NP_650850.1
• Gene: CG4459 / 42377
• FlyBaseID: FBgn0038753
• Length: 632
• Species: Drosophila melanogaster
• Sequence 2: NP_001408283.1
• Gene: lelo-2 / 175300
• WormBaseID: WBGene00022348
• Length: 546
• Species: Caenorhabditis elegans
• Alignment Length: 545
• Identity: 113/545 - (20%)
• Similarity: 209/545 - (38%)
• Gaps: 115/545 - (21%)

  Fly    31 WQLRTILLIFLCKIPS------AWFTAIIIYTAPYPWKGELVC-HPADWNVSRSQ------TEHV 82
            |...::...:.|::||      .::|.::.:|.         | :.||.||..|:      |.|.
 Worm    39 WTFASVDTPYRCRLPSDLPEKEPYYTTLLNFTK---------CTNDADANVPISEYGKPGVTCHY 94

  Fly    83 DRNHPLWQDARSTDRLFNVDVCNAYSNSLARGFVRSHGQEWNASQSKEPGGQSSLPCEHVEHRTD 147
            ||                   |....|......:..|.:                    ||:
 Worm    95 DR-------------------CTLPDNETCHEHIFDHSK--------------------VEY--- 117

  Fly   148 YKSLISQFDLICSRRVLVALTQSFHALGALIGGLMAYSALKKISPRRLMLLGMIGQIFCGNLTGL 212
              :.:.::::.|.|..:.|..|:.:.:|.:.|.........:|..:::..|.::.||.|..|..:
 Worm   118 --TAVQRWEITCDRSWIKATIQAAYYVGQMAGSTTFGMLGDRIGRKKVFFLAIVIQITCAYLIAI 180

  Fly   213 VDTYQLHIYFRCLTSIFCALMYTSGQFILNDITSGKARIIVVTLSELFWSMGLVLLPAISIYFDN 277
            ...:.|:...|..|......::.....|..::...|.|.:...::.||:::|.:.|...:|||.|
 Worm   181 APYWWLYALARAGTGFSHPGIFVIAVVIGMELVGPKYRKLASVITGLFFALGQIFLGIEAIYFTN 245

  Fly   278 WSYLYVAISSSLIVLVWLHRW--IADAPRWLLQHQRVEAALRQLLESATYNNRKVPLTLDVQL-- 338
            :..|:|.|:|.  .|::|..|  :.::.|||:..:|.:.|...|.::|:.|...:|.....||
 Worm   246 YQILHVVIASP--ALLFLSYWWLVPESARWLVSQKRYKEADEVLQKAASVNGTVLPENWWEQLDD 308

  Fly   339 -TMYANDLDQKSKQKHSYCQVWDGETKRSQLVYIHLIWGG-AMVLYNIILLMIRNLGAQQVHVNT 401
             |...........:|.:...::.....|.:.:.:..:|.. :||.|.  :.|..|:....::||.
 Worm   309 STTGGGGAPGAPTKKLTGADLFRTPELRKRTLVVFFLWPVISMVYYG--MAMKANVLGGDIYVNF 371

  Fly   402 AAMGFAEMVGLFVGLYLILYTRRHWRWAGNLMIIAGLSTYLIWLLPETERNSRRVGLELVFWLIL 466
            ....|.|:..||:...||....|....||.| .|||....:.||:          |..:..|:.:
 Worm   372 IFAAFVEIPALFIVYLLIDRIGRRLILAGGL-FIAGACLLVNWLM----------GDNVQLWMAI 425

  Fly   467 ------KIANSASIAVLTTCTSEI------------VSKEKRV-VLMLSVIS------FSRVCLL 506
                  |.:.:...|.:.|.:.|:            .|...|| .:..|.||      |.:|.::
 Worm   426 TQMAFTKGSITGVYAAIYTYSPELFPTVIRNTAMGFCSTIARVGAIAASYISMWIAEQFGKVFMI 490

  Fly   507 FCPFLSCLTVIHHLVPITIL-ATMG 530
            . || .|:.|:..::.:..| .|||
 Worm   491 I-PF-GCMAVLAAVMTLLFLPETMG 513

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4459	NP_650850.1	MFS_SLC22	139..540	CDD:340875	94/424 (22%)
lelo-2	NP_001408283.1	MFS_SLC22	107..508	CDD:340875	91/442 (21%)