Protein Alignment CG4459 and K05F1.6

DIOPT Version :9

• Sequence 1: NP_650850.1
• Gene: CG4459 / 42377
• FlyBaseID: FBgn0038753
• Length: 632
• Species: Drosophila melanogaster
• Sequence 2: NP_001342018.1
• Gene: K05F1.6 / 173977
• WormBaseID: WBGene00019408
• Length: 858
• Species: Caenorhabditis elegans
• Alignment Length: 689
• Identity: 147/689 - (21%)
• Similarity: 263/689 - (38%)
• Gaps: 116/689 - (16%)

  Fly    12 RKSSPELDVVE-----QVNGSFGRWQLRTILLIFLCKIPSAWFTAIIIYTAPYPWKGELVCHPAD 71
            ||.....|.::     .:.|....||:...:||.|.:||.|.|...::|....|   |..|....
 Worm   191 RKEGKPTDPIDFEGILNIIGGCRWWQIWIYVLIALQQIPHAMFNLNVVYMMYDP---EFQCMVPG 252

  Fly    72 WNVSRSQTEHVDRNHP-LW--QDAR---------STDRLFNVDVCNAYSNSLAR-GFVRSHGQEW 123
            :|.:...|  :..:.| ||  .|.:         ::|..:..|.|..|..|..| ..:|....|.
 Worm   253 FNDTNDTT--ISSHGPYLWGVDDIKNISFVFPNANSDGAYQRDSCYFYERSEERYRQLRRMPLET 315

  Fly   124 NASQS-KEPGGQSSLPCEHVEHRTDYKSLISQFDLICSRRVLVALTQSFHALGALIGGLMAYSAL 187
            ..|:: |:...:......|.|.....:::::.|:|:|...........|:::|.|:|.::...|.
 Worm   316 AMSEAWKDVAPKKKCQAYHFEKDVMVETIVTDFNLVCDSWFAKGHAHMFYSIGYLLGCVLGGIAS 380

  Fly   188 KKISPRRLMLLG------MIGQIFCGNLTGLVDTYQLHIYFRCLTSIFCALMYTSGQFILNDITS 246
            .||. |:..::|      |:|.....|     |.|.:.:..|.|::|.......:...:..:||.
 Worm   381 DKIG-RKPTIIGFGILSSMLGVFLPFN-----DYYPMFLLIRLLSAICNEAADLAAYTLCMEITG 439

  Fly   247 GKARIIVVTLSELFWSMGLVLLPAISIYFDNWSYLYVAISSSLIVLVWLHRWIADAPRWLLQHQR 311
            .|.|.:|.::.:..|::|..||..|:....:|..:.|..:....:.:.....|.::||||:...|
 Worm   440 TKYRAMVGSMLQAPWALGYALLALIAYLTKSWKTIQVIAAGLHFMSIIFICSIPESPRWLMVQNR 504

  Fly   312 VEAALRQLLESATYNNRKVP-------------LTLDVQLTMY-ANDLDQKSKQKHSYCQVWDGE 362
            |..| .:::..|.   |:.|             |..|::|..: ...|::|:..|..:..::..:
 Worm   505 VSEA-EEVIRKAC---REPPFPFNMCTTSKCGNLPSDLELVSHRERKLNKKNGGKIGFLDLFTMK 565

  Fly   363 TKRSQLVYIHLIW-GGAMVLYNIILLMI------RNLGAQQVHVNTAAMGFAEMVGLFV------ 414
            ..|.:.:.:.::: ..|:|.|.:::.:.      |.|.....|:|....|..|:..||.
 Worm   566 ELRYRTISVCIVFMATALVYYGLVMALSDQSAPGRTLFTGYFHLNNGIAGAIEIPTLFACVWMMQ 630

  Fly   415 -----GLYLILYTRRHWRWAGNLMIIAGLSTYLIWLLPETERNSRRVGLELVFWLILKIANSASI 474
                 .|.|.|.|      :|..:|:|.||..           |....|.|.|....|||...:.
 Worm   631 LGRKKALMLTLIT------SGLFIIVAMLSMV-----------SGHYMLALAFMYFGKIAVQGAF 678

  Fly   475 AVLTTCTSEI---VSKEKRVVLMLSVISFSRVCLLFCPFLSCLTVIHHLVPITILATMGWIYGLA 536
            .:|...|||:   |.:...|.:...|..|......:...||.:::  .:||:.|.|......|:.
 Worm   679 NILYIFTSELYPTVVRNTAVGVTSMVARFGSGLSSYIALLSNISL--PIVPMIIFAVFSLFAGML 741

  Fly   537 LRRLNRYYWNTEQPQISQVPTPNTY---------RRQSAIILRRCSTVSSDCSAYSNELLSNFER 592
            :..|         |:.|:.|.|.|.         .:|...::.|...........|..|..|...
 Worm   742 VFVL---------PETSEKPLPETLDDAINFLEPTKQVNCMMGRFGVFGHQKMTKSISLTENPST 797

  Fly   593 NMAVSIADIWHINFHPSSEIEMEVEQSGPEAHRAHSSET 631
            |   .|||:..:: ..||.|...:.:.....:..::|.|
 Worm   798 N---DIADLKPLS-RRSSAITRRMTERASVIYSRNASRT 832

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4459	NP_650850.1	2A0119	26..536	CDD:273328	124/564 (22%)
		MFS	164..540	CDD:119392	89/416 (21%)
K05F1.6	NP_001342018.1	MFS_SLC22	333..746	CDD:340875	95/450 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160163012
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D704438at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24064
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.950