DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4459 and Ust5r

DIOPT Version :9

Sequence 1:	NP_650850.1	Gene:	CG4459 / 42377	FlyBaseID:	FBgn0038753	Length:	632	Species:	Drosophila melanogaster
Sequence 2:	NP_599207.2	Gene:	Ust5r / 171398	RGDID:	620985	Length:	552	Species:	Rattus norvegicus

Alignment Length:	539	Identity:	102/539 - (18%)
Similarity:	207/539 - (38%)	Gaps:	131/539 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    19 DVVEQVNGSFGRWQLRTILLIFLCKIPSAWFTAIIIYTAPYP----WKGELVCHPADWNVSRSQT 79
            :::.|| ||.||:|:..:..:||..:.....:.|..:||..|    |.      |...||:
  Rat     5 ELLNQV-GSLGRFQILQMAFVFLINVSVVPHSTIENFTAAIPSHRCWV------PILDNVT---- 58

  Fly    80 EHVDRNHP--LWQD-----ARSTDRLFNVDVCNAYSNSLARGFVRSHGQEWNASQSKEPGGQSSL 137
              |..||.  |.||     :...|....:|.|..::..      :.|..:.|.:.|......:.
  Rat    59 --VSDNHSRILNQDKLLKISIPLDSHLRLDKCRRFAQP------QWHLLDLNDTFSSVTEADTE- 114

  Fly   138 PCEH--VEHRTDYKS-LISQFDLICSRRVLVALTQSFHALGALIGGLMAYSALKKISPRRLMLLG 199
            ||..  |..|:::.| .::::||:|..:||.::|:....:||.|||::......:...:.::...
  Rat   115 PCVDGWVYDRSNFHSTTVTEWDLVCESQVLNSVTKFSFMIGAFIGGIVNGPLSDRFGRKFVLKCA 179

  Fly   200 MIGQIFCGNLTGLVDTYQLHIYFRCLTSIFCALMYTSGQFILNDITSGKARIIVVTLSELFWSMG 264
            ::.........|....:.::...|.|..:....:..:...::.:.||.|...::..::....|.|
  Rat   180 LLQMAITETCVGFASNFFIYCSLRFLAGMTFEPILVNSNLLMFEWTSHKFLAMMSVIAPCAGSFG 244

  Fly   265 LVLLPAISIYFDNWSYLYVAISSSLIVLVWLHRWIADAPRWLLQHQRVEAALRQLLESATYNNRK 329
            .::|..::..|.||.:|.:|:|..:...:.|.||::::.|||:...:.:..|::|.:.|..|..|
  Rat   245 SMILAGLAFQFQNWHHLQLAMSVPIFFFLILTRWLSESARWLIVTNKPQKGLKELRKVAHMNGMK 309

  Fly   330 VP---LTLDVQLTMYANDLDQKSKQKHSYCQVWDGETKR-------------------------- 365
            ..   ||::|..|....:| :.:|.:.|...::.....|
  Rat   310 NSGDNLTMEVVRTSMKREL-EAAKARPSPRDLFHTPILRKRICAMSFMRILFMLSIFGMSLHLQH 373

  Fly   366 --SQLVYIHLIWGGAMVLYNII----------------LLMIRNL-------------------- 392
              |.::.:..:...:.:|:::|                ::.:|.:
  Rat   374 LSSNIMLLQFVVSASSLLFSVIGPYVFNRMGRRITQMVVMTLRGICILTAVFVPQEMQILRITVV 438

  Fly   393 -----------GAQQVHVN--------TAAMGFAEMVG----LFVGLYLILYT---RRHWRWAGN 431
                       |..::|.|        ..|:|...|.|    ....|::||.:   ...|.:.|.
  Rat   439 TLAGAFSALSFGVNRLHTNELLPTTLRATAIGVIGMFGNSGFFLAPLFMILASYSPNLPWIFYGG 503

  Fly   432 LMIIAGLSTYLIWLLPETE 450
            ..|:.|   :.::|||||:
  Rat   504 FSILNG---FTVFLLPETK 519

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4459	NP_650850.1	2A0119	26..536	CDD:273328	100/532 (19%)
CG4459	NP_650850.1	MFS	164..540	CDD:119392	64/380 (17%)
Ust5r	NP_599207.2	MFS_OAT	109..516	CDD:340932	69/411 (17%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166347091
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.840