Protein Alignment CG4459 and SLC22A31

DIOPT Version :9

• Sequence 1: NP_650850.1
• Gene: CG4459 / 42377
• FlyBaseID: FBgn0038753
• Length: 632
• Species: Drosophila melanogaster
• Sequence 2: NP_001371692.1
• Gene: SLC22A31 / 146429
• HGNCID: 27091
• Length: 446
• Species: Homo sapiens
• Alignment Length: 384
• Identity: 85/384 - (22%)
• Similarity: 143/384 - (37%)
• Gaps: 110/384 - (28%)

  Fly   151 LISQFDLICSRRVLVALTQSFHALGALIG-------------------------GLMAYSALKKI 190
            |...::|:|.....|.|.|..|.||.|:|                         ||.|..||...
Human     5 LSQNWNLVCGDGWKVPLEQVSHLLGWLLGCVILGAGCDRFGRRAVFVASLVLTTGLGASEALAAS 69

  Fly   191 SPRRLMLLGMIGQIFCGNLTGLVDTYQLHIYFRCLTSIFCALMYTSGQFILNDITSGKARIIVVT 255
            .|..|:|..:.|    |.|.|            .|.:::.|.:         ::.....|:....
Human    70 FPTLLVLRLLHG----GTLAG------------ALLALYLARL---------ELCDPPHRLAFSM 109

  Fly   256 LSELFWSMGLVLLPAISIYFDNWSYL--YVAISSSLIVLVW-LHRWIADAPRWLLQHQRVEAALR 317
            .:.||..:|.:|||.::....:|..|  ..|:.|.|::|.| ......::|.|||...:| |..|
Human   110 GAGLFSVVGTLLLPGLAALVQDWRLLQGLGALMSGLLLLFWGFPALFPESPCWLLATGQV-ARAR 173

  Fly   318 QLL------------ESATYNNRKVPLTLDVQLTMYANDLDQKSKQKHSYCQVWDGETK---RSQ 367
            ::|            :|:...|     :|..:|||    |..:|.|...:..:....|:   |:.
Human   174 KILWRFAEASGVGPGDSSLEEN-----SLATELTM----LSARSPQPRYHSPLGLLRTRVTWRNG 229

  Fly   368 LV--YIHLIWGGAMVLYNIILLMIRNLGAQQVHVNTAAMGFAEMVGL-FVGLYLILYT-----RR 424
            |:  :..|:.||....:.      |:|..|   |.|..:.:....|| ...|..:|.|     ||
Human   230 LILGFSSLVGGGIRASFR------RSLAPQ---VPTFYLPYFLEAGLEAAALVFLLLTADCCGRR 285

  Fly   425 HWRWAGNLMIIAGLSTYLI----WLLPETERNSRRVGLELVFWLILKIANSASIAVLTT 479
            .....|.:  :.||::.|:    ..||         |..::|..:|.:..|.:::.|::
Human   286 PVLLLGTM--VTGLASLLLLAGAQYLP---------GWTVLFLSVLGLLASRAVSALSS 333

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4459	NP_650850.1	2A0119	26..536	CDD:273328	85/384 (22%)
		MFS	164..540	CDD:119392	82/371 (22%)
SLC22A31	NP_001371692.1	MFS	9..383	CDD:421695	84/380 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165153490
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.930