Protein Alignment CG4459 and SLC22A9

DIOPT Version :9

• Sequence 1: NP_650850.1
• Gene: CG4459 / 42377
• FlyBaseID: FBgn0038753
• Length: 632
• Species: Drosophila melanogaster
• Sequence 2: NP_543142.2
• Gene: SLC22A9 / 114571
• HGNCID: 16261
• Length: 553
• Species: Homo sapiens
• Alignment Length: 588
• Identity: 112/588 - (19%)
• Similarity: 219/588 - (37%)
• Gaps: 111/588 - (18%)

  Fly    31 WQLRTILLIFLCKIPSAWFTAIII--YTAPYP----W-------------KGEL-------VCHP 69
            |:.:.:..:||.....|.:...::  :||..|    |             .|.|       :..|
Human    14 WRFQILQTVFLSIFAVATYLHFMLENFTAFIPGHRCWVHILDNDTVSDNDTGALSQDALLRISIP 78

  Fly    70 ADWNVSRSQTEHVDRNHPLWQDARSTDRLFNVDVCNAYSNSLARGFVRSHGQEWNASQSKEPGGQ 134
            .|.|:...:....  .||.||                        .:..:|...|.|.:
Human    79 LDSNMRPEKCRRF--VHPQWQ------------------------LLHLNGTFPNTSDA------ 111

  Fly   135 SSLPCEH--VEHRTDYKS-LISQFDLICSRRVLVALTQSFHALGALIGGLMAYSALKKISPRRLM 196
            ...||..  |..|..:.| :::::||:|..:.|.::.:.....|.::||::. ..|.....||.:
Human   112 DMEPCVDGWVYDRISFSSTIVTEWDLVCDSQSLTSVAKFVFMAGMMVGGILG-GHLSDRFGRRFV 175

  Fly   197 LLGMIGQI-FCGNLTGLVDTYQLHIYFRCLTSIFCALMYTSGQFILNDITSGKARIIVVTLSELF 260
            |.....|: ..|....|..|:          .|:|:|.:.||...::.||: ...:|....:..|
Human   176 LRWCYLQVAIVGTCAALAPTF----------LIYCSLRFLSGIAAMSLITN-TIMLIAEWATHRF 229

  Fly   261 WSMGLVL-----------LPAISIYFDNWSYLYVAISSSLIVLVWLHRWIADAPRWLLQHQRVEA 314
            .:||:.|           |..::....:|..|.:.:|....|:.....|:.::.|||:.:.:.|.
Human   230 QAMGITLGMCPSGIAFMTLAGLAFAIRDWHILQLVVSVPYFVIFLTSSWLLESARWLIINNKPEE 294

  Fly   315 ALRQLLESA---TYNNRKVPLTLDVQLTMYANDLDQKSKQKHSYCQVWDGETKRSQLVYIHLIWG 376
            .|::|.::|   ...|.:..|||::..:....:|:...|:|.|.|::........::..:.....
Human   295 GLKELRKAAHRSGMKNARDTLTLEILKSTMKKELEAAQKKKPSLCEMLHMPNICKRISLLSFTRF 359

  Fly   377 GAMVLYNIILLMIRNLGAQQVHVNTAAMGFAEMVGLFVGLYLILYTRRHWRWAGN--LMIIAGLS 439
            ...:.|..:.|.:::|| ..|.:.....|...::...|..:.:.|..|.   |..  ||.:..:.
Human   360 ANFMAYFGLNLHVQHLG-NNVFLLQTLFGAVILLANCVAPWALKYMNRR---ASQMLLMFLLAIC 420

  Fly   440 TYLIWLLPETERNSRRV----GLELVFWLILKIANSASIAVLTTCTSEIVSKEKRVVLMLSVISF 500
            ...|..:|:..:..|.|    ||.     ...:||:.:.|    ..:|::....|...|....:|
Human   421 LLAIIFVPQEMQTLREVLATLGLG-----ASALANTLAFA----HGNEVIPTIIRARAMGINATF 476

  Fly   501 SRVCLLFCPFLSCLTVIHHLVPITILATMGWIYGLALRRL----NRYYWNTEQPQISQVPTPNTY 561
            :.:.....|.:..|:|....:|..|.....:|.|.|...|    |:..::|.|.:.::...|...
Human   477 ANIAGALAPLMMILSVYSPPLPWIIYGVFPFISGFAFLLLPETRNKPLFDTIQDEKNERKDPREP 541

  Fly   562 RRQ 564
            :::
Human   542 KQE 544

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4459	NP_650850.1	2A0119	26..536	CDD:273328	106/554 (19%)
		MFS	164..540	CDD:119392	79/396 (20%)
SLC22A9	NP_543142.2	Sugar_tr	11..527	CDD:331684	109/569 (19%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	528..553		2/17 (12%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165153496
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.840