DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG4459 and LOC100490946

DIOPT Version :9

Sequence 1:	NP_650850.1	Gene:	CG4459 / 42377	FlyBaseID:	FBgn0038753	Length:	632	Species:	Drosophila melanogaster
Sequence 2:	XP_031756488.1	Gene:	LOC100490946 / 100490946	-ID:	-	Length:	517	Species:	Xenopus tropicalis

Alignment Length:	638	Identity:	136/638 - (21%)
Similarity:	232/638 - (36%)	Gaps:	157/638 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    15 SPELDVVEQVNGSFGRWQ--LRTILLIFLCKIPSAWFTAIIIYTAPYPWKGELVCHPADWNVSRS 77
            |..|.|::: :..|..:|  :.|:|...||.:.:..|..:.....| |:.    |..   |::..
Frog     2 SMALSVLDK-DSLFSPFQAIMVTLLSAPLCFVGTHNFMPVFAAAVP-PYN----CRS---NMTMD 57

  Fly    78 QTEHVDRNHPLWQDARSTDRLFNVDVCNAYSNSLARGFVRSHGQEWNASQSKEPGGQSSLPCE-- 140
            |..:.:                  |.|..|.:||:                     .|:.|||
Frog    58 QPRYPE------------------DPCTQYVSSLS---------------------NSTKPCEEG 83

  Fly   141 -HVEHRTDYKSLISQFDLICSRRVLVALTQSFHALGALIGGLMAYSALKKISPRRLMLLGMIGQI 204
             ..:|.....::||::||:|.|:.|..:.||.:..|.|:|..: |.||.....||.|:|..:.||
Frog    84 WEYDHSIFTSTIISEWDLVCDRQTLKEVAQSVYMAGVLVGAAV-YGALADRFGRRAMILCSLLQI 147

  Fly   205 FCGNLTGLVDTYQLHIY--FRCLTSI-FCALMYTSGQFILNDI------TSGKARIIVVTLSELF 260
             .|...|:..:..:.:|  ||.||.: .|.|       |:||:      |..:.|.||..:....
Frog   148 -AGMGIGVALSPNIIVYCLFRFLTGMGICGL-------IINDLGLAMEWTPRRYRPIVSMIQGYG 204

  Fly   261 WSMGLVLLPAISIYFDNWSYLYVAISSSLIVLVWLHRWIADAPRWLLQHQRVEAALRQLLESATY 325
            .:.|.::|..::.....|.:|.:..|....:...|..|:.::.|||...:....||..|...|..
Frog   205 LTCGAIILVGLAYAIRGWRWLQLTASLPYFIFFLLMCWVPESARWLSLKKHSNQALANLNRVAKI 269

  Fly   326 NNRKV--PLTLDVQLTMYANDLDQKSKQ----KHSYCQVWDGETKRSQLVYIHLIWGGAMVLYNI 384
            |.||.  |:||:    |...| ||.|.:    |.:...::...|.|:..:.:.|.|..:...:..
Frog   270 NGRKEGGPITLE----MLKLD-DQHSTKAMTTKLTPLDLFRTPTMRTITLILSLSWFSSSFGFFA 329

  Fly   385 ILLMIRNLGAQQVHVNTAAMG-------FAEMVGLFVGLYLILYTRRHWRWAGNLMIIAGLSTYL 442
            |.|.:...|...........|       .|.:...::|..|.:         ..|:|.||.....
Frog   330 IALDVDRFGLSLYLTQGVFAGSELPIRILATITAFYIGRRLTI---------SFLLIFAGTLLLC 385

  Fly   443 IWLLPETERNSRRVGLELVFWLILKIANSASIAVLTTCTSEIVSKEKRVVLMLSVISFSRVCLLF 507
            ...:|:.         .|:..:||.:...||:.....|:....::....||..:.:.|:.:.:..
Frog   386 TMAVPKD---------MLLLQMILTVLAKASLGSCIVCSYLYTAEVYPTVLRQTGLGFTNMMMRL 441

  Fly   508 CPFLSCLTVIHHL----VPITILATMGWIYGLALRRLNRYYWNTEQPQISQVPTPNTYRRQSAII 568
            ...:|.|.:|..:    :|:.|.|.|..|.||.:..|         |:....|..:|.....:
Frog   442 GAIISPLVMITRVYVSFLPMVIFAVMPIISGLPILLL---------PETLNCPLMDTVEEVES-- 495

  Fly   569 LRRCSTVSSDCSAYSNELLSNFERNMAVSIADIWHINFHPSSEIEMEVEQSGP 621
                                   ||.        .:||    :|::..|.|||
Frog   496 -----------------------RNR--------ELNF----QIKIPKENSGP 513

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4459	NP_650850.1	2A0119	26..536	CDD:273328	119/540 (22%)
CG4459	NP_650850.1	MFS	164..540	CDD:119392	92/401 (23%)
LOC100490946	XP_031756488.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	1	1.000