Protein Alignment CG4459 and slc22a7b.3

DIOPT Version :10

• Sequence 1: NP_650850.1
• Gene: CG4459 / 42377
• FlyBaseID: FBgn0038753
• Length: 632
• Species: Drosophila melanogaster
• Sequence 2: XP_001337264.4
• Gene: slc22a7b.3 / 100001772
• ZFINID: ZDB-GENE-131120-103
• Length: 546
• Species: Danio rerio
• Alignment Length: 586
• Identity: 122/586 - (20%)
• Similarity: 225/586 - (38%)
• Gaps: 107/586 - (18%)

  Fly    19 DVVEQVNGSFGRWQLRTILLIFLCK--IPSAWFTAIIIYTAPYPWKGELVCHPADWNV------- 74
            |::.::|| |||:|...:.:.|:.:  ||..:..:..|...|        .|..|.:.
Zfish     5 DLITEING-FGRFQKMILCISFVGRFIIPCHFLLSNFIAAIP--------SHHCDISFLDADGLF 60

  Fly    75 -SRSQTEHVDRNHPLWQDARSTDRLFNVDVCNAYSNSLARGFVRSHGQEWNASQSKEPGGQSSLP 138
             :.::.|.:..:.|..:|.....       |:.:|:...:..:       |:|.|      |.||
Zfish    61 GNLTEEERLIVSVPTQEDGSPVS-------CHMFSHPQFQLLI-------NSSSS------SDLP 105

  Fly   139 ---CE---HVEHRTDYKSLISQFDLICSRRVLVALTQSFHALGALIGGLMAYSALKKISPRRLML 197
               |:   |.::.|...:|.:|:||:|..|.|.....:...:|.:.|... :..:.....|:.||
Zfish   106 VVECQNGWHFDNSTFISTLATQWDLVCDNRGLNKAVATIFFVGVMFGAAF-FGGMSDRFGRKPML 169

  Fly   198 LGMIGQIFCGNLTGLVDTYQLHIYFRCLTSIFCALMYTSG---------QFILN----DITSGKA 249
            |       ...::|:  .:.|...|....::|..|.:.||         ..:||    ||   :.
Zfish   170 L-------VSYISGM--AFALASVFSTSFTMFAVLRFFSGFTITGIVIVSSVLNLEWVDI---EH 222

  Fly   250 RIIVVTLSELFWSMGLVLLPAISIYFDNWSYLYVAISSSLIVLVWLHRWIADAPRWLLQHQRVEA 314
            |.:|..:..:.|::|...|..|:.:..:|.:|.||::|.|::...|..|:.::.|||:.:..||.
Zfish   223 RRLVSIIDSMAWAVGSTSLALIAYFIRDWRWLTVAVTSPLVLCTILWWWVPESARWLIANGDVEK 287

  Fly   315 ALRQLLESATYNNRKVPLTLDVQLTMYANDLDQKSKQKHSYCQVWDGETKRSQLVYIHLIWGGAM 379
            | ...|......|||..:|..::....|..:..:.|:|::|..:......|...:....:|....
Zfish   288 A-HYYLHKCAVMNRKAEVTSRIKPEALAISVSDQGKKKYTYLDLVRTPKMRKLAMLTGTVWFCVA 351

  Fly   380 VLYNIILLMIRNLGAQQVHVNTAAMGFAEMVGLFVGLYLILYTRRHWRWAGNLMIIAGLSTYLIW 444
            .:...|.|.|.:.|. .:::.....|..|:....:..||:....|....|| ..:.||:|..:..
Zfish   352 TMTYGISLNITSFGL-NMYLTQFVYGAIEVPSKLIVYYLLEKIGRRKTEAG-AQLFAGISLMINI 414

  Fly   445 LLPETERNSRRVGLELVFWLILKIANSASIAVLTTCTSEIVSKEKRVVLM----LSVISF-SRVC 504
            .:|:.:...|.|...|          ....||...||..:.|.|....::    :...|| :|:.
Zfish   415 FIPKDQWIGRTVVAVL----------GKGFAVAAFCTIVLYSSELYPTVLRQNGMGYNSFLARLG 469

  Fly   505 LLFCPFLSCLTVIHHLVPITILATMGWIYGLALRRLNRYYWNTEQPQISQVP-----------TP 558
            :...|.:..|.........|||.::..|..:..       ||..:.:...:|           ||
Zfish   470 VSVAPLVLLLDTFWGQFSQTILCSVALIASVVA-------WNLPETRDRCLPETIEDVEGTGKTP 527

  Fly   559 N 559
            |
Zfish   528 N 528

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4459	NP_650850.1	MFS_SLC22	139..540	CDD:340875	91/421 (22%)
slc22a7b.3	XP_001337264.4	None