Protein Alignment CG4462 and Orct2

DIOPT Version :10

• Sequence 1: NP_650849.1
• Gene: CG4462 / 42376
• FlyBaseID: FBgn0038752
• Length: 573
• Species: Drosophila melanogaster
• Sequence 2: NP_651238.2
• Gene: Orct2 / 42890
• FlyBaseID: FBgn0086365
• Length: 567
• Species: Drosophila melanogaster
• Alignment Length: 552
• Identity: 128/552 - (23%)
• Similarity: 226/552 - (40%)
• Gaps: 98/552 - (17%)

  Fly    47 VGDFGIWQLRTILIIFLCKIPAAWFMACIIFTGPELYPGSEFTCDTSYLTSSS--------NSSF 103
            :||||.:|.....:|.|..||.|:.....:|    |....:|.|...:...||        |.|:
  Fly    10 LGDFGRYQKIIYFLICLTSIPVAFHKLAGVF----LLAKPDFRCALPFENGSSYDLPTHLWNLSY 70

  Fly   104 SISDNQCYV------------LDESTGTSSECEQFNYVSS--FDSLIMQFNLVCLRDIFVAWTQY 154
            ..::...|.            :..|:..:..|..:.|..|  .:|.:.::||||.||...|.:..
  Fly    71 PENERCSYYDVDYTEEYLNGSIPRSSNETKTCSSYVYDRSKYLNSAVTEWNLVCGRDFMAATSDS 135

  Fly   155 WHLFGVLVGGVM--------GTKMMLGISPRSTYCVGAVAQILCGVVTGYARDFSLHCAFRCLSA 211
            ..:.|||:|.::        |.|.:|..|        .|.|:|.||:.|.|.::..:...|.:..
  Fly   136 LFMLGVLLGSIVFGQLSDKYGRKPILFAS--------LVIQVLFGVLAGVAPEYFTYTFARLMVG 192

  Fly   212 VCCAIMFTAGQAIFADITAGMHRIGAIILYDTFWSIGVILLPGLSSFFNSWSLIYVGITFPTIML 276
            ...:.:|.....:..::.....|:.|.|....|:|:|.:|....:.|.:.|..:.:.:|.|. ::
  Fly   193 ATTSGVFLVAYVVAMEMVGPDKRLYAGIFVMMFFSVGFMLTAVFAYFVHDWRWLQIALTLPG-LI 256

  Fly   277 ILLLYW-TPDSPRWLL-----------RHAADRF-----SIDNVEQILREGAAINDRSFKIPPDF 324
            .:..|| .|:|.||||           ...|.||     |.:.:.::|.||....:::
  Fly   257 FMFYYWIIPESARWLLLKGRKDCAIANMQKAARFNKVEISDEALSELLDEGENSEEKA------- 314

  Fly   325 RQQLEQLSERLKAQPPPAPWTEL-WKGKRAKTHMVAAHLALAFFVIN--FMGMLLNIRSFGRDYL 386
            :|:||  .:.|...|||:.|... :...|.||.::    .|.:.|.:  :.|:..|..:.|.:.|
  Fly   315 KQKLE--DQELDEGPPPSVWDLFCYPNLRRKTLLI----FLDWLVTSGVYYGLSWNTSNLGGNVL 373

  Fly   387 VPNTIAMGFSEIIGCFLALHFTLKHNKWKWQCAGVFNILAGILGCMGWIFTNADSMDADLKV--- 448
            : |.:..|..| |..::.|..||  |:|     |..:||.|.|...|.      |:.|.:.:
  Fly   374 L-NFVISGAVE-IPAYIFLLLTL--NRW-----GRRSILCGCLVMAGL------SLLATVIIPQR 423

  Fly   449 --SLWMIIATIPKAAVSCAQSMILACMNELMPANKKQLFVFSVVTWARVWLLSAPFFNVLRKIDT 511
              :|.:..|.:.|.|::.:...:.....|..|...:.:.:.:....||:..:.|||.|.|..|..
  Fly   424 MHTLIVACAMLGKLAITASYGTVYIFSAEQFPTVVRNVALGAASMVARISGMMAPFLNFLATIWK 488

  Fly   512 AMSLTSYCVFSILGGICTSLLLTPRLSVSPVV 543
            .:.|......:::.|:.:  ||.|.....|::
  Fly   489 PLPLLICGSLTLVAGLLS--LLLPETHNKPML 518

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4462	NP_650849.1	MFS_SLC22	123..533	CDD:340875	104/444 (23%)
Orct2	NP_651238.2	2A0119	11..520	CDD:273328	128/551 (23%)