Protein Alignment CG4462 and Slc22a25

DIOPT Version :10

• Sequence 1: NP_650849.1
• Gene: CG4462 / 42376
• FlyBaseID: FBgn0038752
• Length: 573
• Species: Drosophila melanogaster
• Sequence 2: NP_620263.1
• Gene: Slc22a25 / 192273
• RGDID: 621104
• Length: 552
• Species: Rattus norvegicus
• Alignment Length: 533
• Identity: 105/533 - (19%)
• Similarity: 206/533 - (38%)
• Gaps: 116/533 - (21%)

  Fly    74 CIIFTGPELYPGSEFTCDTSYLTSSSNSSFSISDNQC---YVLDESTGTSSECEQFNYVSSFDSL 135
            |..|..|:        .|..:|..:.:|........|   :|.|:||..|             ::
  Rat    88 CRRFVQPQ--------WDLLHLNGTFSSVTEPDTEPCVDGWVYDQSTFLS-------------TI 131

  Fly   136 IMQFNLVCLRDIFVAWTQYWHLFGVLVGGVMGTKMMLGISPRSTYCVGAVAQILCGVVTGYARDF 200
            |.:::|||......:..::..|.|:|||.::...:......|......::...:......:|..|
  Rat   132 ITEWDLVCESQSLDSIAKFLFLTGILVGNILYGPLTDRFGRRLILICASLQMAVTETCAAFAPTF 196

  Fly   201 SLHCAFRCLSAVCCAIMFTAGQAIFADITAGMHRIGAIILYDTFWSIGVILLPGLSSFFNSWSLI 265
            .::|:.|.|:.:..:.:.|....:..:.|....:..|..|.....:||..:|.||:....:|..:
  Rat   197 LIYCSLRFLAGISFSTVLTNSALLIIEWTRPKFQALATGLLLCAGAIGQTVLAGLAFTVRNWHHL 261

  Fly   266 YVGITFPTIMLILLLYWTPDSPRWL---------------------LRHAADRFSIDNVEQILRE 309
            ::.::.|...|::...|..:|.|||                     ::::.|..:|:.|..|::|
  Rat   262 HLAMSVPIFFLLVPTRWLSESARWLIMTNKLQKGLKELIKVAHINGMKNSTDVLTIEVVRTIMKE 326

  Fly   310 GAAINDRSFKIPPDFRQQLEQLSERLKAQPPPAPWTELWKGKRAKTHMVAAHLALAFFVI--NFM 372
                             :||      .:|...:.| :|::....:..:..  |:|..||:  :.:
  Rat   327 -----------------ELE------ASQTKSSLW-DLFRTPNLRKRICL--LSLVRFVVWLSVI 365

  Fly   373 GMLLNIRSFGRDYLVPNTIAMGF----SEIIGCFLALHFTLKHNKWKWQCAGVFNILAGILGCMG 433
            |:|:|.:....:..:...: :|.    :.::|.||..|...:.::       :|.|....:..:.
  Rat   366 GLLINFQHLRINVFLLQCL-LGIITIPANLVGIFLVNHLGRRISQ-------LFIISLFGISILA 422

  Fly   434 WIFTNADSMDADLKVSLWMIIATIPKAAVSCAQSMILACMNELMPA--NKKQLFVFSVV--TWAR 494
            .||     :..:::: |.|::||........:.|..|...|||:|.  ....|.|..:.  |.|.
  Rat   423 IIF-----VPQEMQI-LRMVLATFGGVFSFVSVSSALVHANELLPTIIRATALGVIGIAGSTGAA 481

  Fly   495 VWLLSAPFFNVLRKIDTAMSLTSYCVFSILGGICTSLLLTPRLSVSPVVPHLEQRNTKEQSPLNA 559
            :    :|.|.:||....::....|.|.|.|||:.  :||.|              .||.| ||..
  Rat   482 L----SPLFMILRTYSDSLPWIIYGVLSFLGGLV--VLLLP--------------ETKNQ-PLPD 525

  Fly   560 PVWTVESDVNNTR 572
            .:..||::...:|
  Rat   526 SIQDVENEGRASR 538

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4462	NP_650849.1	MFS_SLC22	123..533	CDD:340875	82/440 (19%)
Slc22a25	NP_620263.1	MFS_OAT	109..506	CDD:340932	84/453 (19%)