Protein Alignment CG4462 and slc22a6

DIOPT Version :10

• Sequence 1: NP_650849.1
• Gene: CG4462 / 42376
• FlyBaseID: FBgn0038752
• Length: 573
• Species: Drosophila melanogaster
• Sequence 2: XP_002937540.1
• Gene: slc22a6 / 100487511
• XenbaseID: XB-GENE-5842250
• Length: 552
• Species: Xenopus tropicalis
• Alignment Length: 591
• Identity: 118/591 - (19%)
• Similarity: 230/591 - (38%)
• Gaps: 112/591 - (18%)

  Fly    43 IADVVGDFGIWQLRTILII---------------FLCKIPAAWFMACII--------FTGP---- 80
            |.:.:|..|.:|:..::::               |...||.   ..|.|        ||||
 Frog     6 ILESIGGMGRYQVIHVVLLSLPVFMLASHNLMQNFTAAIPR---HRCQINGSFEETNFTGPWLRA 67

  Fly    81 --ELYPGSEFTCDTSYLTSSSNSSFSISDNQCYVLDE-STGTSSECEQFNYVSSFDSLIMQFNLV 142
              .:.|..||:....|.|...:   .:.||....:|| .|.|..:...:::.....::|.|::||
 Frog    68 LVPMKPTGEFSKCLRYTTPQYH---LLMDNFTQNVDELETETCVDGWVYDHSEFASTIITQWDLV 129

  Fly   143 C----LRDIFVAWTQYWHLFGVLVGGVM--GTKMMLGISPRSTYCVGAVAQILCGVVTGYARDFS 201
            |    :|.:    .|..::.|||||.|:  |.....|..|.:.:  ..:...:.|:...::.::.
 Frog   130 CNHRRMRQV----AQSIYMAGVLVGSVVFGGLSDKFGRRPLNIW--SNLQMSVTGICAAFSPNYI 188

  Fly   202 LHCAFRCLSAVCCA-IMFTAGQAIFADITAGMHRIGAIILYDTFWSIGVILLPGLSSFFNSWSLI 265
            .:|.||.|:....: |:..:...|...|..| :|..........:::|.::|.||:.....|..:
 Frog   189 WYCIFRFLTGTALSGIVLNSYSLIVEWIPTG-NRAFTSTATGYCYTMGQLVLVGLAFMIRDWHWL 252

  Fly   266 YVGITFPTIMLILLLYWTPDSPRWLLRHAADRFSIDNVEQILREGAAINDRSFKIPPDFRQQLEQ 330
            .:..:.|.....|..:|.|:|.|||:.......:.    :.|::.|.||.:            ::
 Frog   253 QLAASLPFFFYFLYSWWIPESGRWLVLSGKPEVAC----KALKKVAKINGK------------KE 301

  Fly   331 LSERLKAQPPPAPWTELWKGKRAKTHMVAAH--------------------LALAFFVINF--MG 373
            ..|:|.        .|:.|....:....:.|                    ::..:|..:|  .|
 Frog   302 AGEKLT--------VEVLKSSMQREISASKHSTYSVLDLVRTPVVRRISFCISCTWFSTSFAYYG 358

  Fly   374 MLLNIRSFGRD-YLVPNTIAMGFSEIIGCFLALHFTLKH-NKWKWQCAGVFNILAGILGCMGWIF 436
            :.|:::|||.. |::  .|..|..:|...|.: :|.:.: .:...|...:  |||||.     |.
 Frog   359 LALDLQSFGVSIYII--QIIFGTVDIPAKFFS-YFVMTYIGRRVLQALTL--ILAGIA-----IL 413

  Fly   437 TNADSMDADLKVSLWMIIATIPKAAVSCAQSMILACMNELMPANKKQLFVFSVVTWARVWLLSAP 501
            .|. .:..|.: ::...:|...|..::.:.:.:.....||.|...:|..:......||:..:.||
 Frog   414 VNI-CVPQDYQ-TVRTSMAVFGKGCLAASFNCLFLYTGELYPTVIRQSGMGLGTMMARLGGIIAP 476

  Fly   502 FFNVLRKIDTAMSLTSYCVFSILGGICTSLL-LTPRLSVSPVVPHLEQRNTKEQS-PLNAPVWTV 564
            ...:...|..::.|..:....||.||....| .|..:.:...:..:|..:.|::: .|:|.:...
 Frog   477 LAQMTGDIYHSLPLIIFGCLPILSGIAGCFLPETLGVPLPETIEDVESSDKKQKNVELSAKMPLK 541

  Fly   565 ESDVNN 570
            |:::.|
 Frog   542 ETELAN 547

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4462	NP_650849.1	MFS_SLC22	123..533	CDD:340875	87/441 (20%)
slc22a6	XP_002937540.1	MFS_SLC22A6_OAT1_like	102..508	CDD:341004	88/448 (20%)