Protein Alignment CG4465 and SLC22A16

DIOPT Version :9

• Sequence 1: NP_650847.1
• Gene: CG4465 / 42374
• FlyBaseID: FBgn0038750
• Length: 577
• Species: Drosophila melanogaster
• Sequence 2: NP_149116.2
• Gene: SLC22A16 / 85413
• HGNCID: 20302
• Length: 577
• Species: Homo sapiens
• Alignment Length: 572
• Identity: 112/572 - (19%)
• Similarity: 212/572 - (37%)
• Gaps: 136/572 - (23%)

  Fly    59 DDVITHIMGNFGPWQLRSLLILFLCKIP---------AAWFM------AC--------ILFTAPD 100
            :.:..|: |:||.:|   .::.|:|...         |:.||      .|        ::|....
Human     7 EGIYDHV-GHFGRFQ---RVLYFICAFQNISCGIHYLASVFMGVTPHHVCRPPGNVSQVVFHNHS 67

  Fly   101 LYPEEEYKCDTTAFGPDVNSTVSLDHCYVMVNYGESAYAMRQCRK-------------------- 145
            .:..|    ||.|    :.|:...|:..|.:..|| .:.:.:|.:
Human    68 NWSLE----DTGA----LLSSGQKDYVTVQLQNGE-IWELSRCSRNKRENTSSLGYEYTGSKKEF 123

  Fly   146 -----FLY--TTGFHSLTMEFDLVCLCDFFVAWSQYWHLFGLLIGGVAATKLMRVLSPRQIYRTG 203
                 ::|  .|...:...:::|||...:.....|...:||:|:|.|.    ....|.|...|..
Human   124 PCVDGYIYDQNTWKSTAVTQWNLVCDRKWLAMLIQPLFMFGVLLGSVT----FGYFSDRLGRRVV 184

  Fly   204 IWCLLMCSLLMGLVKDFSLHCGLRCLAAVSCCFMITSGQYIFG-----DITAGKYRVGTLILYDC 263
            :|.......|.|:...|::.. ...:||.....|:.||..:.|     :....|.|....:....
Human   185 LWATSSSMFLFGIAAAFAVDY-YTFMAARFFLAMVASGYLVVGFVYVMEFIGMKSRTWASVHLHS 248

  Fly   264 FWALGLILLPGLASNAPSW---QHIYLGVTLSLLVIVFLLPWTPDSPRWQLQHTK--EAQLAIER 323
            |:|:|.:|:........:|   |.|...||:..::..::|   |::|.|.|...:  |||    :
Human   249 FFAVGTLLVALTGYLVRTWWLYQMILSTVTVPFILCCWVL---PETPFWLLSEGRYEEAQ----K 306

  Fly   324 TVGILLEAARTNGRMHKVSKELPQQLE--------ELRERMLEPMPAVHWMHLWMGQRRSTFHLV 380
            .|.|:.:..|.:.  .|:|:.|...|:        |:::..|.     :..:.|...:|:
Human   307 IVDIMAKWNRASS--CKLSELLSLDLQGPVSNSPTEVQKHNLS-----YLFYNWSITKRT----- 359

  Fly   381 AVHMALATFMVVNTG-------LLLHVRSFGREHLVSNTLAMGLAEMLGCFLALHLTFNLSERKW 438
                 |..:::..||       .|..|...|.|:|  |...:|:.| :..:..:.:..:...|:.
Human   360 -----LTVWLIWFTGSLGFYSFSLNSVNLGGNEYL--NLFLLGVVE-IPAYTFVCIAMDKVGRRT 416

  Fly   439 QWAGGFAIVVGCIGSICWFLAEEDMPEVYGLTLGLLMASLPQAAVACAQSMILACLGELVPMEQR 503
            .    .|..:.|....|..:..  :|:.:.: ||::.|.:.:.|:..|..:|.....||.|...|
Human   417 V----LAYSLFCSALACGVVMV--IPQKHYI-LGVVTAMVGKFAIGAAFGLIYLYTAELYPTIVR 474

  Fly   504 SCLSFSAVTWARVWQLSASFLTLLRQVSPALSLSAFCLLVILGGLGTCCLVT 555
            |....|.....|:..:.|.|         ::.||:..:.:....:||..|::
Human   475 SLAVGSGSMVCRLASILAPF---------SVDLSSIWIFIPQLFVGTMALLS 517

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4465	NP_650847.1	2A0119	67..553	CDD:273328	110/560 (20%)
		MFS	169..>303	CDD:119392	31/141 (22%)
SLC22A16	NP_149116.2	Sugar_tr	14..535	CDD:331684	111/564 (20%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	543..577

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165153432
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24064
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.940