Protein Alignment CG4465 and slc22a21

DIOPT Version :9

• Sequence 1: NP_650847.1
• Gene: CG4465 / 42374
• FlyBaseID: FBgn0038750
• Length: 577
• Species: Drosophila melanogaster
• Sequence 2: NP_001295487.1
• Gene: slc22a21 / 799908
• ZFINID: ZDB-GENE-091118-62
• Length: 546
• Species: Danio rerio
• Alignment Length: 566
• Identity: 121/566 - (21%)
• Similarity: 211/566 - (37%)
• Gaps: 137/566 - (24%)

  Fly    52 NLADDNDDDVITHIMGNFGPWQLRSLLILFLCKIPAAWFMACILFTAPDLYPEEEYKCDTTAFGP 116
            ||.|..:.   |..:|.:||:|.....:|.|..||..:....|:|..           ||.|...
Zfish     2 NLQDYEEQ---TAFLGAWGPFQKTVFSLLCLSIIPNGFTGLSIVFLG-----------DTPAHHC 52

  Fly   117 DVNSTVSL--------------------DHCY-----VMVNYGE-----------SAYAMRQCRK 145
            .:..|::|                    ..||     ::.||.:           |.....:|..
Zfish    53 RIPETLNLTAGWRNASVPRPQPHGDPRASRCYRLRLDLVKNYSDGGLLPGLDVNVSEIPREECAD 117

  Fly   146 -FLYTTGFHSLTM--EFDLVCLCDFFVAWSQYWHLFGLLIGGVAATKLMRVLSPRQIYRTGIWCL 207
             ::|....:|.|:  |:||||..|:....:......|:|.|.|    :...:|.|...:..::..
Zfish   118 GWIYDKEIYSSTIVSEWDLVCSDDWKSPLTSSIFFCGVLTGSV----ISGPVSDRFGRKIVLFVT 178

  Fly   208 LMCSLLMGLVKDFSLHCGLRCLAAVSCCFMITSGQ-------YIFG-DITAGKYRVGTLILYDC- 263
            :....|..:|:.||....:.|.    ..|::..||       ::.| :|.:...|.....|..|
Zfish   179 MAIQTLFTVVQVFSPSWQIFCF----LFFIVGMGQISNYVAAFVLGMEILSSSVRDVYSTLGVCL 239

  Fly   264 FWALGLILLPGLASNAPSWQHIYLGVTLSLLVIVFLLPWTPDSPRWQLQ--HTKEAQLAIERTVG 326
            |:::|.::||..|.....|:.:.|.:|:.....:.|..:.|:||||.|.  ..:||:..|.:...
Zfish   240 FFSIGYMILPLAAFFLRDWRSLMLALTIPGFFYIPLWWFIPESPRWLLSQGRVQEAEAIIRKAAK 304

  Fly   327 I-----------LLEAARTNGRMHKVSKELPQQLEELRERMLEPMPAVHWMHLWMGQRRSTFHLV 380
            |           |:::....|.:...|  :.:.|:....|.:..:..:.||.:.:|....:.:..
Zfish   305 INRVTAPDVIFPLMQSTEDAGGVQSFS--VCELLKSSNIRYMTGLLCLIWMAVSIGYCALSLNTS 367

  Fly   381 AVH-----MALATFMVVNTGLL---LHVRSFGREHLVSNTLAMGLAEMLGCFLALHLTFNLSERK 437
            ::|     ..|.:.:|....||   |.:|...|.|.:::|||:|     |..|.|.|
Zfish   368 SLHGNIYLNCLLSAVVEVPALLMAWLMLRLAPRRHCLASTLALG-----GLVLLLIL-------- 419

  Fly   438 WQWAGGFAIVVGCIGSICWFLAEEDMPEVYGLTLGLLMASLPQAAVACAQSMILACLGELVPMEQ 502
                                |..||...|   ||.|:|  |.:..::.|.|:|.....||.|...
Zfish   420 --------------------LIPEDQSSV---TLALVM--LGKFGLSAAFSIIYPVTAELYPTVL 459

  Fly   503 RSCLSFSAVTWARVWQLSASFLTLLRQVSPALSLSAFCLLVILGGL 548
            |:....:....:||..:||.:...|.....:|.      .:::||:
Zfish   460 RNTALGACSMSSRVGGISAPYFNYLGSYHRSLP------YILIGGI 499

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4465	NP_650847.1	2A0119	67..553	CDD:273328	117/551 (21%)
		MFS	169..>303	CDD:119392	28/142 (20%)
slc22a21	NP_001295487.1	2A0119	14..521	CDD:273328	117/551 (21%)
		MFS	146..511	CDD:119392	87/408 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170588410
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.840