Protein Alignment CG4465 and Slc22a23

DIOPT Version :9

• Sequence 1: NP_650847.1
• Gene: CG4465 / 42374
• FlyBaseID: FBgn0038750
• Length: 577
• Species: Drosophila melanogaster
• Sequence 2: NP_001028339.1
• Gene: Slc22a23 / 73102
• MGIID: 1920352
• Length: 689
• Species: Mus musculus
• Alignment Length: 630
• Identity: 131/630 - (20%)
• Similarity: 221/630 - (35%)
• Gaps: 201/630 - (31%)

  Fly    21 PLDLGHMA---HSFTCTDPKANEVSPQTPHPKANNLADDNDDDVITHIMGNFGPWQLRSLLILFL 82
            ||...|.:   ||..|....|..:           |..|.|..|:..:.|..|.:| ::|::  |
Mouse    52 PLPALHPSGGPHSSCCAATAAPSL-----------LLLDYDGSVLPFLGGLGGGYQ-KTLVV--L 102

  Fly    83 CKIPAAWFMACILFTAPDLYPEEEYKC--------------------------------DTTAFG 115
            ..|||. |:....|:...|..:.::.|                                .|.::|
Mouse   103 TWIPAL-FIGFSQFSDSFLLDQPDFWCRGAGKGTELAGATVTGRWGDMGNWTSPSATPFSTASWG 166

  Fly   116 PDVNSTVSLD-----------------HCYVMVNYGESAYAMRQCRKFLYTTGFHSLTMEFDLVC 163
            ...|.:.|.|                 .|:.. :||            :.|....::..::||||
Mouse   167 TTSNRSNSSDTPPLPSPPGKGNNDSNCDCHAW-DYG------------IRTGLIQNVVSKWDLVC 218

  Fly   164 LCDFFVAWSQYWHLFGLLIGGVAATKLMRVLSPRQIYRTGIWCLLMCSLLMGLVKDFSLHCGLR- 227
            ...:.|..:::..|.||:.|.:....:...:..|.:.......:|:..|.:.|..:.::...||
Mouse   219 DNTWKVHIAKFSLLVGLIFGYLITGCIADWVGRRPVLLFSTIFILIFGLTVALSVNVTMFSTLRF 283

  Fly   228 ----CLAAVSCCFMITSGQYIFGDITAGKYRVGTLILYDCFWAL-GLILLPGLASNAPSWQHIYL 287
                |||.:    ::|...........||..:.|::.  .|.|: |..|:||||:....||
Mouse   284 FEGFCLAGI----ILTLYALRIELCPPGKRFIITMVA--SFVAMAGQFLMPGLAALCRDWQ---- 338

  Fly   288 GVTLSLLVIVFLLP---WT--PDSPRWQLQHTKEAQLAIERTVGILLEAARTN---------GRM 338
             |..:|::..|||.   |:  |:|.|| |..|::    .|....::|...:.|         |.|
Mouse   339 -VLQALIICPFLLMLLYWSIFPESLRW-LMATQQ----FESAKKLILYLTQKNCVSPESDIKGVM 397

  Fly   339 HKVSKELPQQLEELRERMLEPMPAVHWMHLW------------------------MGQRRS---- 375
            .::.|||.:     |.:.:..:..|...:||                        ||....
Mouse   398 PELEKELSR-----RPKKVCIVKVVGTRNLWKNIVVLCVNSLTGYGIHHCFARSMMGHEVKVPLL 457

  Fly   376 --------TFHLVAVHMALATFMVV-----NTGLLLHVRSFGREHLVSNTLAMGLAEMLGCF--- 424
                    |...:|:...||..:||     ..||||    |.....:::.|.:||..::|.:
Mouse   458 ENFYADYYTMASIALASCLAMCLVVKFLGRRGGLLL----FMILTALASLLQLGLLNLIGKYSQH 518

  Fly   425 ----LALHLTFNLSER-KWQWAGGFAIV----VGCIGSICWFLAEEDMPEVYGL-TLGLLMAS-- 477
                |.|.|...:|:. |.:::..|:||    ...:||:..|...|..|.|... .|||::||
Mouse   519 PDSELQLKLAVGMSDSVKDKFSIAFSIVGMFASHAVGSLSVFFCAEITPTVIRCGGLGLVLASAG 583

  Fly   478 ------------------LPQAAVACAQSMILACLGELVPMEQRS 504
                              |.....||...:.:.|:  |:..|.|:
Mouse   584 FGMLTAPIIELHNQKGYFLHHIIFACCTLICIICI--LLLPESRN 626

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4465	NP_650847.1	2A0119	67..553	CDD:273328	120/581 (21%)
		MFS	169..>303	CDD:119392	33/142 (23%)
Slc22a23	NP_001028339.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..55		2/2 (100%)
		2A0119	98..631	CDD:273328	117/572 (20%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	162..188		5/25 (20%)
		MFS	230..>359	CDD:119392	33/139 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167843343
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.930