Protein Alignment CG4465 and Slc22a23

DIOPT Version :9

• Sequence 1: NP_650847.1
• Gene: CG4465 / 42374
• FlyBaseID: FBgn0038750
• Length: 577
• Species: Drosophila melanogaster
• Sequence 2: NP_072146.1
• Gene: Slc22a23 / 64559
• RGDID: 620302
• Length: 689
• Species: Rattus norvegicus
• Alignment Length: 631
• Identity: 134/631 - (21%)
• Similarity: 216/631 - (34%)
• Gaps: 221/631 - (35%)

  Fly    21 PLDLGHMA---HSFTCTDPKANEVSPQTPHPKANNLADDNDDDVITHIMGNFGPWQLRSLLIL-- 80
            ||...|.:   ||..|....|..:           |..|.|..|:..:.|..|.:| ::|::|
  Rat    52 PLPALHPSGGPHSSCCAAAAAPSL-----------LLLDYDGSVLPFLGGLGGGYQ-KTLVVLTW 104

  Fly    81 --------------FLCKIPAAWFM----------ACIL--------FTAPDLYPEEEYKCDTTA 113
                          ||...|..|..          |.:.        :|:|...|     ..|.:
  Rat   105 IPALFIGFSQFSDSFLLDQPNFWCHGAGKGTELAGATVTGRWGDMGNWTSPSATP-----FSTAS 164

  Fly   114 FGPDVNSTVSLD---------------HCYVMVNYGESAYAMRQCRKFLY--TTGF-HSLTMEFD 160
            :|...|.:.|.|               :|              :|..:.|  .||. .::..::|
  Rat   165 WGTTSNRSNSSDTPPLPSPPGKGNNDSNC--------------ECHAWDYGIRTGLVQNVVSKWD 215

  Fly   161 LVCLCDFFVAWSQYWHLFGLLIG--------GVAATKLMRVLSPRQIYRTGIWCLLMCSLLMGLV 217
            |||    ..||..:...|.||:|        |..|..:.|    |.:....:..:|:..|.:.|.
  Rat   216 LVC----DNAWKVHVAKFSLLVGLIFGYLITGCIADWVGR----RPVLLFSVIFILIFGLTVALS 272

  Fly   218 KDFSLHCGLR-----CLAAVSCCFMITSGQYIFGDITAGKYRVGTLILYDCFWAL-GLILLPGLA 276
            .:.::...||     |||.:    ::|...........||..:.|::.  .|.|: |..|:||||
  Rat   273 VNVTMFSTLRFFEGFCLAGI----ILTLYALRIELCPPGKRFIITMVA--SFVAMAGQFLMPGLA 331

  Fly   277 SNAPSWQHIYLGVTLSLLVIVFLLP---WT--PDSPRWQLQHTKEAQLAIERTVGILLEAARTN- 335
            :....||     |..:|::..|||.   |:  |:|.|| |..|::    .|....::|...:.|
  Rat   332 ALCRDWQ-----VLQALIICPFLLMLLYWSIFPESLRW-LMATQQ----FESAKKLILYLTQKNC 386

  Fly   336 --------GRMHKVSKELPQQLEELRERMLEPMPAVHWMHLW----------------------- 369
                    |.|.::.|||.:     |.:.:..:..|...:||
  Rat   387 VSPESDIKGVMPELEKELSR-----RPKKVCIVKVVGTRNLWKNIVVLCVNSLTGYGIHHCFARS 446

  Fly   370 -MGQRRS------------TFHLVAVHMALATFMVV-----NTGLLLHVRSFGREHLVSNTLAMG 416
             ||....            |...:|:...||..:||     ..||||    |.....:::.|.:|
  Rat   447 MMGHEVKVPLLENFYADYYTMASIALASCLAMCLVVRFLGRRGGLLL----FMILTALASLLQLG 507

  Fly   417 LAEMLGCF-------LALHLTFNLSER-KWQWAGGFAIV----VGCIGSICWFLAEEDMPEVYGL 469
            |..::|.:       |.|.|...:|:. |.:::..|:||    ...:||:..|...|..|.|...
  Rat   508 LLNLIGKYSQHPDSELQLKLAVGMSDSVKDKFSIAFSIVGMFASHAVGSLSVFFCAEITPTVIRC 572

  Fly   470 -TLGLLMAS--------------------LPQAAVACAQSMILACL 494
             .|||::||                    |.....||...:.:.|:
  Rat   573 GGLGLVLASAGFGMLTAPIIELHNQKGYFLHHIIFACCTLICIICI 618

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4465	NP_650847.1	2A0119	67..553	CDD:273328	123/582 (21%)
		MFS	169..>303	CDD:119392	37/150 (25%)
Slc22a23	NP_072146.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..55		2/2 (100%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	162..188		5/25 (20%)
		MFS_SLC22A23	187..608	CDD:341002	102/467 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166346857
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.930