Protein Alignment CG4465 and Slc22a21

DIOPT Version :9

• Sequence 1: NP_650847.1
• Gene: CG4465 / 42374
• FlyBaseID: FBgn0038750
• Length: 577
• Species: Drosophila melanogaster
• Sequence 2: NP_062697.1
• Gene: Slc22a21 / 56517
• MGIID: 1929481
• Length: 564
• Species: Mus musculus
• Alignment Length: 520
• Identity: 108/520 - (20%)
• Similarity: 197/520 - (37%)
• Gaps: 132/520 - (25%)

  Fly    58 DDDVITHIMGNFGPWQLRSLLILFL-------------------------CKIP------AAWFM 91
            |.|.:|..:|.:|.:|   .||.||                         |:||      :||..
Mouse     3 DYDEVTAFLGEWGTFQ---RLIFFLLSASIIPNGFTGLSAVFLTAIPEHRCRIPDTVNLSSAWRN 64

  Fly    92 ACILFTAPDLYPEEEYKC---------DTTAFGPDVNSTVSL-----DHCYVMVNYGESAYAMRQ 142
            ..|.....| .||...||         :.:..|.:....|.|     ::|.....|.:..
Mouse    65 HSIPMETKD-GPEVPQKCRRYRLATIANFSELGLEPGRDVDLEQLEQENCLDGWEYDKDI----- 123

  Fly   143 CRKFLYTTGFHSLTMEFDLVCLCDFFVAWSQYWHLFGLLIGGVAATKLMRVLSPRQIYRTGIWCL 207
               ||.|     :..|:||||..|:....:..:...|:|:|...:.:|......:.|
Mouse   124 ---FLST-----IVTEWDLVCKDDWKAPLTTSFFYVGVLLGSFISGQLSDRFGRKNI-------- 172

  Fly   208 LMCSLLMGLVKDFSLHCGLRCLAAVSCCF--------MITSGQ-------YIFG-DITAGKYRVG 256
                    |....::|.|...:...|..|        ::..|.       ::.| ::.:...|:.
Mouse   173 --------LFLTMAMHTGFSFIQVFSVNFEMFTLLYTLVGMGHISNYVAAFVLGTEMLSKSVRII 229

  Fly   257 TLILYDC-FWALGLILLPGLASNAPSWQHIYLGVTLSLLVIVFLLPWTPDSPRWQLQ--HTKEAQ 318
            ...|..| |:|.|.::||..|.....|:.:.|.:||..::...|..:.|:||||.:.  ..|||:
Mouse   230 FATLGVCIFFAFGFMVLPLFAYFIREWRRLLLAITLPGVLCGALWWFIPESPRWLISQGRIKEAE 294

  Fly   319 LAIERTVGILLEAARTNGRMHKVSKELPQQLEELRERMLEPMPAVHWMHLWMGQRRSTFHLVAVH 383
            :       |:.:||:.||.:...:...|.:..:|::.. ...|..|  |::...|.....::.:
Mouse   295 V-------IIRKAAKINGIVAPSTIFDPSETNKLQDDS-SKKPQSH--HIYDLVRTPNIRILTI- 348

  Fly   384 MALATFMVVNTGLLLHVRSFG--------REHLVSNTLAMGLAEMLGCFLALHLTFNLSERKWQW 440
            |::..::.::.|.      ||        ..::..|...:...|:....||..|..::| |::..
Mouse   349 MSIILWLTISVGY------FGLSLDTPNLNGNIYVNCFLLAAVEVPAYVLAWLLLQHVS-RRYSM 406

  Fly   441 AGGFAIVVGCIGSICWFLAEEDMP-EVYGLTLGLLMASLPQAAVACAQSMILACLGELVPMEQRS 504
            ||  ::.:|  ||:  .|..:.:| :::.|:..|:|..  :..:..|.||:.....||.|...|:
Mouse   407 AG--SLFLG--GSV--LLLVQLVPSDLHYLSTTLVMVG--KFGITSAYSMVYVYTAELYPTVVRN 463

  Fly   505  504
            Mouse   464  463

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4465	NP_650847.1	2A0119	67..553	CDD:273328	105/511 (21%)
		MFS	169..>303	CDD:119392	26/150 (17%)
Slc22a21	NP_062697.1	2A0119	12..523	CDD:273328	105/511 (21%)
		MFS	123..513	CDD:119392	82/396 (21%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	532..564

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167843603
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D704438at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.850