Protein Alignment CG4465 and SLC22A11

DIOPT Version :9

• Sequence 1: NP_650847.1
• Gene: CG4465 / 42374
• FlyBaseID: FBgn0038750
• Length: 577
• Species: Drosophila melanogaster
• Sequence 2: NP_060954.1
• Gene: SLC22A11 / 55867
• HGNCID: 18120
• Length: 550
• Species: Homo sapiens
• Alignment Length: 426
• Identity: 106/426 - (24%)
• Similarity: 167/426 - (39%)
• Gaps: 77/426 - (18%)

  Fly   154 SLTMEFDLVCLCDFFVAWSQYWHLFGLLIGGVAATKLMRVLSPRQIYRTG-----IWCLLMCSLL 213
            ::..::||||........||...:.|:|:|..    :..:||    ||.|     .||.|..: :
Human   127 TIVAKWDLVCSSQGLKPLSQSIFMSGILVGSF----IWGLLS----YRFGRKPMLSWCCLQLA-V 182

  Fly   214 MG----LVKDFSLHCGLRCLAAVSCCFMITSGQYIFGDITAGKYRVGTLILYDCFWALGLILLPG 274
            .|    ....|.::||||.:||.....:..|...:..:.|....|..|:.:..|.::.|...|.|
Human   183 AGTSTIFAPTFVIYCGLRFVAAFGMAGIFLSSLTLMVEWTTTSRRAVTMTVVGCAFSAGQAALGG 247

  Fly   275 LASNAPSWQHIYLGVTLSLLVIVFLLPWTPDSPRWQLQHTKEAQLAIERTVGILLEAARTNGRMH 339
            ||.....|:.:.|..::....|..:..|.|:|.||.:...|..|...|     |.:.||.||  |
Human   248 LAFALRDWRTLQLAASVPFFAISLISWWLPESARWLIIKGKPDQALQE-----LRKVARING--H 305

  Fly   340 KVSKELPQQ--LEELRERML---EP--------MPAVHWMHLWMGQRRSTFHLVAVHMALATFMV 391
            |.:|.|..:  :..::|.:.   ||        :|.:.|        ||...||.....|.::.
Human   306 KEAKNLTIEVLMSSVKEEVASAKEPRSVLDLFCVPVLRW--------RSCAMLVVNFSLLISYY- 361

  Fly   392 VNTGLLLHVRSFGREHLVSNTLAMGLAEMLG-CFLALHLTFNLSERKWQWAG-----GFAIVVGC 450
               ||:..::|.||:..:...| .|..:.|| ...||.|:| |..|..| ||     |.||:..
Human   362 ---GLVFDLQSLGRDIFLLQAL-FGAVDFLGRATTALLLSF-LGRRTIQ-AGSQAMAGLAILAN- 419

  Fly   451 IGSICWFLAEEDMPEVYGLTLGLLMASLPQAAVACAQSMILACLGELVPMEQRSCLSFSAVTWAR 515
                  .|..:|:.     ||.::.|.|.:.....:.:.:.....||.|...|........|..|
Human   420 ------MLVPQDLQ-----TLRVVFAVLGKGCFGISLTCLTIYKAELFPTPVRMTADGILHTVGR 473

  Fly   516 VWQLSASFLTLLRQVSPALS------LSAFCLLVIL 545
            :..:....:.:.||..|.|.      :|....||:|
Human   474 LGAMMGPLILMSRQALPLLPPLLYGVISIASSLVVL 509

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4465	NP_650847.1	2A0119	67..553	CDD:273328	106/426 (25%)
		MFS	169..>303	CDD:119392	34/142 (24%)
SLC22A11	NP_060954.1	Sugar_tr	11..523	CDD:331684	106/426 (25%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	531..550

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165153208
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.840