DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4465 and oatx

DIOPT Version :9

Sequence 1:	NP_650847.1	Gene:	CG4465 / 42374	FlyBaseID:	FBgn0038750	Length:	577	Species:	Drosophila melanogaster
Sequence 2:	XP_017208528.1	Gene:	oatx / 555218	ZFINID:	ZDB-GENE-070115-1	Length:	567	Species:	Danio rerio

Alignment Length:	526	Identity:	110/526 - (20%)
Similarity:	203/526 - (38%)	Gaps:	75/526 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    66 MGNFGPWQLRSLLILFLCKIPAAWFMACIL---FTAPDLYPEEEYKCD--TTAFGPDVNSTVSLD 125
            :|.||.:|:..:.:|   .||.....:..|   |||.  .||...:..  |||..   :||.:|.
Zfish    10 VGGFGRFQMIHVTLL---SIPGLLMASQNLLNNFTAG--VPEHHCRIPNVTTAMN---DSTTTLL 66

  Fly   126 HCYVMVNYGESAYAMRQCRKF-------------------LYTTG------------FHSLTMEF 159
            ..::.:   :|:..:.:|.::                   |.|.|            ..|:..|:
Zfish    67 RAFIPL---DSSLTLSKCSRYKDTQWHLITDKLSHGNATELQTEGCADGWTYDKSEFISSIVSEW 128

  Fly   160 DLVCLCDFFVAWSQYWHLFGLLIGGVAATKLMRVLSPRQIYRTGIWCLLMCSLL---MGLVKDFS 221
            ||||........||..::.|:|.|.:....|......:.:.   ||.....:||   ..|...:.
Zfish   129 DLVCTLRPLKQMSQTIYMGGVLTGAIIFGGLSDRFGRKALL---IWSYFQLALLGSFTALAPSYV 190

  Fly   222 LHCGLRCLAAVSCCFMITSGQYIFGDITAGKYR--VGTLILYDCFWALGLILLPGLASNAPSWQH 284
            ::|..|.|..:|...:|.:...:..:....|.|  ||||..:  |:..|.::|.|:|.:...|:.
Zfish   191 VYCIFRFLTGMSVSGVILNAVSLKVEWIPTKTRTLVGTLSSF--FFTFGQMVLAGVAYSLRDWRK 253

  Fly   285 IYLGVTLSLLVIVFLLPWTPDSPRWQLQHTKEAQLAIERTVGILLEAARTNGRMHKVSKELPQQL 349
            |.:.|.|...:......|..:|.||.:.:.:.     |..:.:|...|:.||:.....|...::|
Zfish   254 IQMAVCLPFFIFFMYSWWFSESARWLVLNGRS-----EEALKLLHRVAKINGKPEMTEKITLEEL 313

  Fly   350 EELRERMLEPMPAVHWMHLWMGQRRSTFHLVAVHMALATFMV--VNTGLLLHVRSFGREHLVSNT 412
            |...::.::...:::.:...:  |..|...:::.:.:..|..  ...||.:.::.|| .::....
Zfish   314 ESHMQKEVQSSKSIYTVFDLL--RTPTMRKISMCLMVVWFSTSFAYYGLAMDLQKFG-VNIYLMQ 375

  Fly   413 LAMGLAEMLGCFLALHLTFNLSERKWQWAGGFAIVVGCIGSICWFLAEEDMPEVYGLTLGLLMAS 477
            :..|..:.....:||.:...|..|..|   |..::|............||| :|....|.:|...
Zfish   376 VIFGAVDFPAKLVALLMLSFLGRRLTQ---GACLLVSASIIFANIFVPEDM-QVTRTALAVLGKG 436

  Fly   478 LPQAAVACAQSMILACLGELVPMEQRSCLSFSAVTWARVWQLSASFLTLLRQVSPALSLSAFCLL 542
            ...|:..|    :....|||.|...|........|.:|:..::|..:.:|..:.|||....:...
Zfish   437 FTSASFTC----VYLFTGELYPTVIRQTGMGFVSTMSRIGSMAAPAVLILDDILPALPSIVYGGS 497

  Fly   543 VILGGL 548
            .::.||
Zfish   498 AVIAGL 503

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4465	NP_650847.1	2A0119	67..553	CDD:273328	110/525 (21%)
CG4465	NP_650847.1	MFS	169..>303	CDD:119392	31/138 (22%)
oatx	XP_017208528.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.910