Protein Alignment CG4465 and SLC22A15

DIOPT Version :9

• Sequence 1: NP_650847.1
• Gene: CG4465 / 42374
• FlyBaseID: FBgn0038750
• Length: 577
• Species: Drosophila melanogaster
• Sequence 2: NP_060890.2
• Gene: SLC22A15 / 55356
• HGNCID: 20301
• Length: 547
• Species: Homo sapiens
• Alignment Length: 551
• Identity: 111/551 - (20%)
• Similarity: 202/551 - (36%)
• Gaps: 152/551 - (27%)

  Fly    66 MGNFGPWQLRSLLILFLCKIPAAWFMACILFTAPDLYPEEE------------YKCDTTAFGPDV 118
            :|..|.:|      ::||      |:..:|.   .||...|            |..|.....|:.
Human    10 VGEMGIYQ------MYLC------FLLAVLL---QLYVATEAILIALVGATPSYHWDLAELLPNQ 59

  Fly   119 ---NSTVSLDHCY---VMVNYGESAYAMRQCRKFLYTTGFHSLTMEFDLVCLCDFFVAWSQYWHL 177
               |.:...|..:   ::...|...:     :...:::.|.|:..|:.|:....:.|:.:..:..
Human    60 SHGNQSAGEDQAFGDWLLTANGSEIH-----KHVHFSSSFTSIASEWFLIANRSYKVSAASSFFF 119

  Fly   178 FGLLIGGVAATKLMRVLSPRQIYRTGIWCLLMCSLLMGLVKDFSLHCGLRCLAAVSCCFMITSGQ 242
            .|:.:|.::..:|......:::|.||....::.::..|....:..             |.:|  :
Human   120 SGVFVGVISFGQLSDRFGRKKVYLTGFALDILFAIANGFSPSYEF-------------FAVT--R 169

  Fly   243 YIFGDITAGKYRVGTLILYDC----FWAL-----GLILLPGLASNA------PSWQHIYLGVTLS 292
            ::.|.:..|...|..::|.:|    :|||     ||....|:|..|      .||:      ||:
Human   170 FLVGMMNGGMSLVAFVLLNECVGTAYWALAGSIGGLFFAVGIAQYALLGYFIRSWR------TLA 228

  Fly   293 LLV-----IVFLLP-WTPDSPRW-----QLQHTKEAQLAIERTVGILLEAARTNGRM-------- 338
            :||     :||||. :.|:||||     :|...:||...|          |:.|.::
Human   229 ILVNLQGTVVFLLSLFIPESPRWLYSQGRLSEAEEALYLI----------AKRNRKLKCTFSLTH 283

  Fly   339 --HKVSKELPQQLEELRERMLEPMPAVHWMHLWMGQRRSTFHLVAVHMALATFM-----VVNTGL 396
              ::..:|....|:..|.|:|            :|           |..:..|:     :|..||
Human   284 PANRSCRETGSFLDLFRYRVL------------LG-----------HTLILMFIWFVCSLVYYGL 325

  Fly   397 LLHVRSFGREHLVSNTLAMGLAEMLGCFLALHLTFNLSERKW----QWAGGFAIVVGCIGSICWF 457
            .|.....|.. :.:|....||.|:....|.::|.    .:||    :....|..:.|....|..|
Human   326 TLSAGDLGGS-IYANLALSGLIEIPSYPLCIYLI----NQKWFGRKRTLSAFLCLGGLACLIVMF 385

  Fly   458 LAEEDMPEVYGLTLGLLMASLPQAAVACAQSMILACLGELVPMEQR-----SCLSFSAVTWARVW 517
            |.|:....|:.:.....::.|.:..::.|.:::.....||.|...|     :|..||     ||.
Human   386 LPEKKDTGVFAVVNSHSLSLLGKLTISAAFNIVYIYTSELYPTVIRNVGLGTCSMFS-----RVG 445

  Fly   518 QLSASFLTLLRQVSPALSLSAFCLLVILGGL 548
            .:.|.|:..|:.|..:|....|....:..||
Human   446 GIIAPFIPSLKYVQWSLPFIVFGATGLTSGL 476

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4465	NP_650847.1	2A0119	67..553	CDD:273328	111/550 (20%)
		MFS	169..>303	CDD:119392	33/154 (21%)
SLC22A15	NP_060890.2	MFS	111..469	CDD:119392	89/421 (21%)
		MFS_1	111..450	CDD:284993	83/402 (21%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	522..547

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165153444
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR24064
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.940