Protein Alignment CG4465 and SLC22A17

DIOPT Version :9

• Sequence 1: NP_650847.1
• Gene: CG4465 / 42374
• FlyBaseID: FBgn0038750
• Length: 577
• Species: Drosophila melanogaster
• Sequence 2: NP_065105.3
• Gene: SLC22A17 / 51310
• HGNCID: 23095
• Length: 649
• Species: Homo sapiens
• Alignment Length: 576
• Identity: 132/576 - (22%)
• Similarity: 202/576 - (35%)
• Gaps: 178/576 - (30%)

  Fly    70 GPWQLRSLLI------------LFLCKIPAAWFMAC------ILFTAPDLYPEEEYKCDTTAFGP 116
            ||....:||.            |.||.:|.. |:|.      |...||.|:      |...||.|
Human    76 GPLSFEALLAQVGALGGGQQLQLGLCCLPVL-FVALGMASDPIFTLAPPLH------CHYGAFPP 133

  Fly   117 DVN--------STVSLDHCYVMVNYGE----------SAYA---MRQCRKFLYTTGFHSLTM--- 157
            :.:        |.||:....:..:...          |.:|   ...|.|.....|...||.
Human   134 NASGWEQPPNASGVSVASAALAASAASRVATSTDPSCSGFAPPDFNHCLKDWDYNGLPVLTTNAI 198

  Fly   158 -EFDLVCLCDFFVAWSQYWHLFGLLIGGVAATKLMRVLSPRQIYRTGIWCLLMCSLLMGLVKDFS 221
             ::||||...:.|...|.     |.|.|.|:..|.......:..|.||     ..|.:|||..
Human   199 GQWDLVCDLGWQVILEQI-----LFILGFASGYLFLGYPADRFGRRGI-----VLLTLGLVGP-- 251

  Fly   222 LHCGLRCLAAVSCCFMITSGQYIFGDITAG---------------KYRVGTLILYDCFWALGLIL 271
              ||:...||.|...::.. :::.|.:.||               ..|:...:..:.....|..|
Human   252 --CGVGGAAAGSSTGVMAL-RFLLGFLLAGVDLGVYLMRLELCDPTQRLRVALAGELVGVGGHFL 313

  Fly   272 LPGLASNAPSWQHIYLGVTLSLLVIVFLLPWTP---DSPRWQL--QHTKEAQLAIERTVGILLEA 331
            ..|||..:..|:.:...:|...::.:| ..|..   :|.||.:  :..:|||..:.    ||.|.
Human   314 FLGLALVSKDWRFLQRMITAPCILFLF-YGWPGLFLESARWLIVKRQIEEAQSVLR----ILAER 373

  Fly   332 ARTNGRMHKVSKELPQQLEELRERMLEPMPA---------VHWMHLWM----------------- 370
            .|.:|:|  :.:|..:.|::|....  |:||         :::.::|.
Human   374 NRPHGQM--LGEEAQEALQDLENTC--PLPATSSFSFASLLNYRNIWKNLLILGFTNFIAHAIRH 434

  Fly   371 -------GQRRSTFHLVAVHMALATFMVVNTGLLLHVRSFGREH--LVSNTLAMGLAE--MLGCF 424
                   |...|.|:|.:: :|..|..:....|.:.|..|||..  |:|.||. |:|.  :||.:
Human   435 CYQPVGGGGSPSDFYLCSL-LASGTAALACVFLGVTVDRFGRRGILLLSMTLT-GIASLVLLGLW 497

  Fly   425 LALHLTFNLSERKWQWAGG------------FAIVVGCIGS-----ICWFLAEEDMP-EVYGLTL 471
            ...|..|   ...|...|.            |: |:|...|     :...||.|.:| .|.|..|
Human   498 DCEHPIF---PTVWAQQGNPNRDLNEAAITTFS-VLGLFSSQAAAILSTLLAAEVIPTTVRGRGL 558

  Fly   472 GLLMA-------SLPQ--------------AAVACAQSMILACLGELVPMEQRSCL 506
            ||:||       |.|.              ...|||...||:.:  |:|..:|..|
Human   559 GLIMALGALGGLSGPAQRLHMGHGAFLQHVVLAACALLCILSIM--LLPETKRKLL 612

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4465	NP_650847.1	2A0119	67..553	CDD:273328	132/576 (23%)
		MFS	169..>303	CDD:119392	31/148 (21%)
SLC22A17	NP_065105.3	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165153301
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.930