Protein Alignment CG4465 and slc22a2

DIOPT Version :9

• Sequence 1: NP_650847.1
• Gene: CG4465 / 42374
• FlyBaseID: FBgn0038750
• Length: 577
• Species: Drosophila melanogaster
• Sequence 2: NP_998315.1
• Gene: slc22a2 / 406424
• ZFINID: ZDB-GENE-040426-2167
• Length: 562
• Species: Danio rerio
• Alignment Length: 624
• Identity: 143/624 - (22%)
• Similarity: 217/624 - (34%)
• Gaps: 207/624 - (33%)

  Fly    67 GNFGPWQLRSLLILFLCKIPAAWFMACILFTAPDLYPEEEYKCDTTAFGPDVN------------ 119
            |.||..|:|......|..||.::....|:|..   :..|.:..|     |.|:
Zfish    12 GTFGRSQIRIFCTFCLVSIPFSFVYVGIVFQG---FTPEHWCRD-----PGVSEIRERCGWSLQD 68

  Fly   120 ---STVSLDHCYVMVNYGESAYAMRQCRKF---LYTTGF-------------------------- 152
               :||.|      :| |.|..:..||.:|   ...||.
Zfish    69 ARRATVPL------IN-GSSGASYSQCGRFDVDWNATGLSCENPDGDFNQSQLSVMPMMSCVDGW 126

  Fly   153 -------HSLTMEFDLVCLCDFFVAWSQYWHLFGLLIGGVA----ATKLMRVLSPRQIYRTGIWC 206
                   .|...||||||...::|...|.....|.|:|.:|    |.|..|:.|
Zfish   127 EYDYVGRQSFVTEFDLVCGDAWYVDMFQATLSIGFLVGSIAIGYLADKYGRMKS----------- 180

  Fly   207 LLMCSLLMGLVKDFSLHCGLRCLAAVSCCFMITSGQYI--------FGDITAGKYRVGTLIL--- 260
            .||.:..:|                |:...:.||..||        ||....|.:.||.:::
Zfish   181 FLMTNFFIG----------------VTGILVATSPNYISLLVFRALFGFGVKGGWMVGYVLITEL 229

  Fly   261 ------------YDCFWALGLILLPGLASNAPSWQHIYLGVTLSLLVIVFLLPW--TPDSPRWQL 311
                        |..|:::|::|||.||....:|:  :|.|..::..|.||..:  .|:||||.|
Zfish   230 VGVDHRRTVGVTYQLFFSMGILLLPLLAYFITNWR--WLQVVFTVPYICFLTYYWFIPESPRWLL 292

  Fly   312 QHTKEAQLAIERTVGILLEAARTNGRMHKVSKELPQQLEELRERMLEPMPAVHWMHLWMGQRRST 376
            ...|.|: |:|.|..|..|..:|          |.:::|.|::..::......:|.|:...:..|
Zfish   293 TQNKIAE-AVEITKSIAKENRKT----------LSKKIETLKDDNIDSGSTASFMDLFKTAKLRT 346

  Fly   377 FHLVAVHMALATFMVVNTGLLLHVRSFGREHLVSNTLAMGLAEMLGCFLALHLTFNLSERKWQWA 441
            :..: :.....|..||..||::.:...|....| :.|..|:.|:...||.| ||.....|:..:|
Zfish   347 YTFI-LSFNWFTSAVVYQGLIMRLGILGGNVYV-DFLISGIVELPAAFLIL-LTIERIGRRLPFA 408

  Fly   442 GGFAIVVGCIGSICWFLAEEDMPEVYGLTLGLLMASLP------QAAVAC--------AQSMILA 492
            ....:.    |:.|                 |:.|.:|      ::||||        |..|::.
Zfish   409 TANIVA----GAAC-----------------LITAFIPDSMFWLKSAVACVGRLGITMAFEMVVF 452

  Fly   493 CLGELVPMEQRSCLSFSAVTWARVWQLSASFLTLLRQVSPALSLSAFCLLVILGGL-----GTCC 552
            ...||.|...|:.......|...|..:.|.|| |.|.....|.|.    |:|.|.|     |...
Zfish   453 VNTELYPTVIRNLGVSVCSTLCDVGGIVAPFL-LYRLAVIWLELP----LIIFGALAFVAGGLVL 512

  Fly   553 LV------------------TRDKEQPPVGAVVNKGQQL 573
            |:                  .|:||.|      .:.|||
Zfish   513 LLPETKGVPLPETIDDIEHPNRNKENP------QQSQQL 545

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4465	NP_650847.1	2A0119	67..553	CDD:273328	135/584 (23%)
		MFS	169..>303	CDD:119392	37/162 (23%)
slc22a2	NP_998315.1	2A0119	12..525	CDD:273328	136/596 (23%)
		MFS	146..515	CDD:119392	104/437 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170588700
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.840