Protein Alignment CG4465 and SLC22A

DIOPT Version :9

• Sequence 1: NP_650847.1
• Gene: CG4465 / 42374
• FlyBaseID: FBgn0038750
• Length: 577
• Species: Drosophila melanogaster
• Sequence 2: NP_649370.1
• Gene: SLC22A / 40437
• FlyBaseID: FBgn0037140
• Length: 568
• Species: Drosophila melanogaster
• Alignment Length: 589
• Identity: 137/589 - (23%)
• Similarity: 216/589 - (36%)
• Gaps: 141/589 - (23%)

  Fly    38 ANEVSPQTPHPKANNLADDNDD---DVITHIMGNFGPWQLRSLLILFLCKIPAAWFMACILFTAP 99
            |:|..|..|..:....|.|::|   |.|...:|.||.:||...|::.|..:..|.|....:|||.
  Fly     3 ASEAPPADPAVEVAPPAKDSEDVTLDAILKHLGQFGRFQLIIFLLICLPMMFHAMFSVTYVFTAA 67

  Fly   100 DLYPE---EEYKCD---TTAFGPDVNSTV-----SLDHC--YVMVNYGESAYAMRQC-------- 143
            .:...   ||  ||   :..:.|..|.::     .||.|  |......:..:::..|
  Fly    68 TVTHRCSVEE--CDLPGSNYYEPHTNWSIPKNGKDLDSCNRYTNSELPQWNHSVDICSADHFTKN 130

  Fly   144 ------RKFLYTTGFHSLTMEFDLVCLCDFFVAWSQYWHL------------FGLLIGGVAATKL 190
                  .:|::.....:::.:|.:.|        ...|.|            ||:.|||..|.:.
  Fly   131 KEACAHNEFVFRDDEVTISNDFGIFC--------DDEWKLSMVGTINNLGQFFGIPIGGFVADRY 187

  Fly   191 MRVLSPRQIYRTGIWCLLMCSLLMGLVKDFSLHCG----------LRCLAAVSCCFMITSGQYIF 245
            .|..|   |...||     ...::|:::.||...|          :......|.||:|..
  Fly   188 GRSFS---IALGGI-----LGAVLGVIRSFSPSYGWFLVFEFLDNMTSSTLYSTCFVIGI----- 239

  Fly   246 GDITAGKYRVGTLILYDCFWALGLILLPGLASNAPSWQ---HIYLGVTLSLLVIVFLLPWTPDSP 307
             ::...|.||....:...|:|:|.:||...|.....|:   .|..|.:|.||...::|   |:|.
  Fly   240 -ELVGPKRRVLACSVITVFYAVGEVLLAMSAKAFHDWRILLRITYGPSLILLAYFWIL---PESV 300

  Fly   308 RWQLQHTKEAQLAIERTVGILLEAARTNGRMHKVSKELP---------------QQLEELRERML 357
            ||.|...||     ||...||..||..|.|      |||               ||..|.|..:.
  Fly   301 RWLLSQGKE-----ERAKNILRRAAHVNKR------ELPESVLDKLVLANRDKLQQSSESRFPIR 354

  Fly   358 EPMPAVHWMHLWMGQRRSTFHLVAVHMALATFMVVNTGLLLHVRSFGREHLVSNTLAMGLAEMLG 422
            |......|            .:....:.....::|..||.|:|.....:. .:|...:.|.|:.|
  Fly   355 EAFKNFKW------------RIANCSLCWIVHVLVYYGLSLNVVLLDGDK-YNNFAYIALVEIPG 406

  Fly   423 CFLALHLTFNLSERKWQWAGGFAIVVG--CIGSICWFLAEEDMPEVYGLTLGLLMASLPQAAVAC 485
            .|:.| |..:...|::... |..:..|  |||:|   ....|.|     .|.|::..:.:..:..
  Fly   407 FFMPL-LIMDRFGRRYSLC-GLMLASGLCCIGTI---FTGADQP-----VLQLVLFLVGKLTITA 461

  Fly   486 AQSMILACLGELVPMEQR-SCLSFSAVTWARVWQLSASFLTLLRQV---SPALSLSAFCLLVILG 546
            :..::.....|:.|...| |.|||.:: ..|...:.|....||.:.   :||:   .|....|:.
  Fly   462 SFQVLYFFASEIYPTNLRNSLLSFCSM-MGRFGSMLAPQTPLLAKYYANAPAM---LFAGAAIVS 522

  Fly   547 GLGT 550
            ||.|
  Fly   523 GLLT 526

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4465	NP_650847.1	2A0119	67..553	CDD:273328	128/557 (23%)
		MFS	169..>303	CDD:119392	37/158 (23%)
SLC22A	NP_649370.1	2A0119	35..540	CDD:273328	128/557 (23%)
		MFS	146..530	CDD:119392	104/444 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45458334
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24064
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.940