Protein Alignment CG4465 and slc22a4

DIOPT Version :9

• Sequence 1: NP_650847.1
• Gene: CG4465 / 42374
• FlyBaseID: FBgn0038750
• Length: 577
• Species: Drosophila melanogaster
• Sequence 2: NP_957143.1
• Gene: slc22a4 / 393822
• ZFINID: ZDB-GENE-040426-1517
• Length: 553
• Species: Danio rerio
• Alignment Length: 621
• Identity: 129/621 - (20%)
• Similarity: 220/621 - (35%)
• Gaps: 180/621 - (28%)

  Fly    58 DDDVITHIMGNFGPWQLRSLLILFLCKIPAAWFMACILFTAPD-----LYPEE------------ 105
            |.|.||..:|.:||:||...|.|.:..:|..:....|:|....     |.||:
Zfish     3 DYDDITSFLGTWGPFQLTVFLALAISILPNGFVGLYIVFVGDTPAHECLIPEQINISSVWRDAAI 67

  Fly   106 ---------------EYKCDTTA------FGPDVN---STVSLDHCYVMVNYGESAYAMRQCRKF 146
                           .|:.||..      :.|:|.   |.:..:.|....:|.:..|.
Zfish    68 PTQMQDGVLKRSSCSRYRLDTLRQLSMLNYTPNVEVNLSQIETEPCVDGWSYSQEFYQ------- 125

  Fly   147 LYTTGFHSLTMEFDLVCLCDFFVAWSQYWHLFGLLIGGVAATKLMRVLSPRQIYRTGIWCLLMCS 211
                  .::..|:||||..::....:...:..|:|:|    |.|...:|.|...|..::.::...
Zfish   126 ------STIVTEWDLVCEREYKGPLTSSIYFCGVLVG----TFLSGQMSDRYGRRPVLFTMMALQ 180

  Fly   212 LLMGLVKDFSLHCGLRCLAAVSCCFMITSGQYIFGDITAGK-----YRVGTLILYDC----FWAL 267
            .:..|::.|            |..:.:.|..|.|...:...     |.:|:.||...    |.:|
Zfish   181 TITILIQMF------------SPSWEVFSAIYFFVGFSGFSNYVVAYVLGSEILSPASRVLFGSL 233

  Fly   268 GLILLPGL--------ASNAPSWQHIYLGVTLSLLVIVFLLPW-TPDSPRWQLQ--HTKEAQLAI 321
            |:.:..|:        |....||:.:.|...|:.| :.|.|.| .|:||||.|.  .|.||:..:
Zfish   234 GVFMGSGIGQMFFPLAAYFIRSWRWLVLTNALTGL-LYFPLWWFIPESPRWLLSQGRTAEAEAVL 297

  Fly   322 ERTVGILLEAARTNGRMHKVSKEL---PQQLEELRERMLEPMPAVHWMHLWMGQRRSTFHLVAVH 383
            .|       ||..|   ...:.|:   ..::||..::.:              |:.|...:::..
Zfish   298 RR-------AAEKN---RVTAPEVIFSSSEIEEAAKKRI--------------QKHSILDILSNC 338

  Fly   384 MALATFMVVNTGLLLHVRSFGREHLVSNTLAMGLAEMLGCFL------------ALHLTFNLSER 436
            .|::|.::.:  ||..|.:.....|:.||..:.....|..||            ||.|.| .|.|
Zfish   339 NAVSTILICS--LLWMVITMSYYALILNTTNLHGNPYLNFFLSAVVEVPAYIIAALLLRF-CSRR 400

  Fly   437 KWQWA----GGFAIVVGCIGSICWFLAEEDMPEVYGLTLGLLMASLPQAAVACAQSMILACLGEL 497
            ..|.:    ||..|          |:.:....|:.||...|.|  |.:..|..|..::.|...||
Zfish   401 ICQASTLLLGGALI----------FIIQLIPTELQGLATALEM--LGKLCVTAAFCVVYAVTSEL 453

  Fly   498 VPMEQRSCLSFSAVTWARVWQLSASFLTLLRQVSPALSLSAFCLLVILGGL----GTCCLVTRDK 558
            .|...|:....|....||:..:.:.|:..|.      :...:...:::|||    |...|:..:.
Zfish   454 FPTVVRNMAMGSCSMTARIGSIISPFIIYLG------NYYRYIPYIVIGGLALFSGVMSLLLPES 512

  Fly   559 E---------------------QPPVGAVVNKGQQL 573
            :                     :||..:..:|.:.|
Zfish   513 KGKVLPETIAQMQSVRGLRRCRKPPAASTEDKSKVL 548

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4465	NP_650847.1	2A0119	67..553	CDD:273328	120/569 (21%)
		MFS	169..>303	CDD:119392	31/151 (21%)
slc22a4	NP_957143.1	2A0119	12..520	CDD:273328	121/582 (21%)
		MFS	144..510	CDD:119392	94/427 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170588460
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.840