Protein Alignment CG4465 and SLC22A10

DIOPT Version :9

• Sequence 1: NP_650847.1
• Gene: CG4465 / 42374
• FlyBaseID: FBgn0038750
• Length: 577
• Species: Drosophila melanogaster
• Sequence 2: NP_001034841.3
• Gene: SLC22A10 / 387775
• HGNCID: 18057
• Length: 541
• Species: Homo sapiens
• Alignment Length: 455
• Identity: 99/455 - (21%)
• Similarity: 175/455 - (38%)
• Gaps: 79/455 - (17%)

  Fly   142 QCRKF-------LYTTG-FHS-----------------------LTMEFDLVCLCDFFVAWSQYW 175
            :||:|       |:..| .||                       :..::||||......:..|:.
Human    87 KCRRFVHPQWQLLHLNGTIHSTSEADTEPCVDGWVYDQSYFPSTIVTKWDLVCDYQSLKSVVQFL 151

  Fly   176 HLFGLLIGGVAATKLMRVLSPRQIYRTGIWCLLMCSL---LMGLVKDFSLHCGLRCLAAVSCCFM 237
            .|.|:|:||:....:......|.|.|   ||||..::   .......|.::|.||.||..|...:
Human   152 LLTGMLVGGIIGGHVSDRFGRRFILR---WCLLQLAITDTCAAFAPTFPVYCVLRFLAGFSSMII 213

  Fly   238 ITSGQYIFGDITAGKYRVGTLILYDCFWALGLILLPGLASNAPSWQHIYLGVTLSLLVIVFLLPW 302
            |::......:......:...:||.....::|.|:|.|||.....||.:::..::...|...|..|
Human   214 ISNNSLPITEWIRPNSKALVVILSSGALSIGQIILGGLAYVFRDWQTLHVVASVPFFVFFLLSRW 278

  Fly   303 TPDSPRWQLQHTKEAQLAIERTVGILLEAARTNGRMHKVSKELPQQLEELRERMLEPMPAVHWMH 367
            ..:|.||.:...|     ::..:..|.:.|||||..   :.|....:|.:|..|.|.:.|
Human   279 LVESARWLIITNK-----LDEGLKALRKVARTNGIK---NAEETLNIEVVRSTMQEELDA----- 330

  Fly   368 LWMGQRRST----FHLVAVHMALATFMVV---NT----GLLLHVRSFGREHLVSNTLAMGLAEML 421
               .|.::|    |...::...:...:.:   ||    |.:::::..|....:...|...:|.::
Human   331 ---AQTKTTVCDLFRNPSMRKRICILVFLRFANTIPFYGTMVNLQHVGSNIFLLQVLYGAVALIV 392

  Fly   422 GCFLAL---HLTFNLSERKWQWAGGFAIVVGCIGSICWFLAEEDMPEVYGLTLGLLMASLPQAAV 483
            .|...|   |:...:|:..:.:..|.:|:...      |:.:|..      ||.:.:|.|.....
Human   393 RCLALLTLNHMGRRISQILFMFLVGLSILANT------FVPKEMQ------TLRVALACLGIGCS 445

  Fly   484 ACAQSMILACLGELVPMEQRSCLSFSAVTWARVWQLSASFLTLLRQVSPALSLSAFCLLVILGGL 548
            |...|.:.....||:|...|:..|...:|.:|:....|..|..|......|....:.:..|:|||
Human   446 AATFSSVAVHFIELIPTVLRARASGIDLTASRIGAALAPLLMTLTVFFTTLPWIIYGIFPIIGGL 510

  Fly   549  548
            Human   511  510

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4465	NP_650847.1	2A0119	67..553	CDD:273328	99/455 (22%)
		MFS	169..>303	CDD:119392	33/136 (24%)
SLC22A10	NP_001034841.3	2A0119	11..526	CDD:273328	99/455 (22%)
		MFS	143..516	CDD:119392	88/399 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165153468
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.840