Protein Alignment CG4465 and Slc22a12

DIOPT Version :10

• Sequence 1: NP_650847.1
• Gene: CG4465 / 42374
• FlyBaseID: FBgn0038750
• Length: 577
• Species: Drosophila melanogaster
• Sequence 2: XP_063125948.1
• Gene: Slc22a12 / 365398
• RGDID: 621628
• Length: 643
• Species: Rattus norvegicus
• Alignment Length: 537
• Identity: 118/537 - (21%)
• Similarity: 187/537 - (34%)
• Gaps: 150/537 - (27%)

  Fly    42 SPQTPHPKANNLADDNDDDVITHIMGNFGPWQLRSLLILFLCKIPAAWFMACILFTAPDLYPEEE 106
            |...||.:......||.....: |.|:||    |.  :|....||          ..||..|
  Rat   131 SAAVPHHRCWVPLLDNSTSQAS-IPGDFG----RD--VLLAVSIP----------PGPDQRP--- 175

  Fly   107 YKC-------------DTTAFGPDVNSTVSLDHCYVMVNYGESAYAMRQCRKFLYTTGFHSLTME 158
            ::|             :|||.......|...:..:|   |..|.:     |..:.||
  Rat   176 HQCLRFRQPQWQLIESNTTATNWSDADTEPCEDGWV---YDHSTF-----RSTIVTT-------- 224

  Fly   159 FDLVCLCDFFVAWSQYWHLFGLLIG----GVAATKL--MRVLSPRQIYRTGIWCLLMCSL---LM 214
            :||||........:|...|.|:|:|    |.|:.:.  .|||:         |..|:.|:   :.
  Rat   225 WDLVCDSQALRPMAQSIFLAGILVGAAVCGHASDRFGRRRVLT---------WSYLLVSVSGTIA 280

  Fly   215 GLVKDFSLHCGLRCLAAVSCCFMITSGQYIFGDITAGKYRVGTLILYDCFWALGLILLPGLASNA 279
            .|:..|.|:|..|.|.|.:...::.:...:..:.|:.:.....:.|....::.|.:|...:|...
  Rat   281 ALMPTFPLYCLFRFLVASAVAGVMMNTASLLMEWTSAQAGPLMMTLNALGFSFGQVLTGSVAYGV 345

  Fly   280 PSWQHIYLGVTLSLLVIVFLLPWTPDSPRWQLQHTKEAQLAIERTVGILLEAARTNGRMHKVSKE 344
            .||:.:.|.|:....:......|.|:|.||.:            |||.|.::.|...|:..|::.
  Rat   346 RSWRMLQLAVSAPFFLFFVYSWWLPESARWLI------------TVGRLDQSLRELQRVAAVNRR 398

  Fly   345 LPQ----QLEELRERMLEPMPAVHWMHLWMGQRRSTFHLVAVHMALATFMVVNTGLLLHVRSFGR 405
            ..:    .:|.||..|.|..         .|.:..                ...|.|||......
  Rat   399 KAEADTLTVEVLRSAMQEEP---------NGNQAG----------------ARLGTLLHTPGLRL 438

  Fly   406 EHLVSNTLAMGLAEMLGCFLALHLTFNLSERKWQWAGGFAIVVGCIGSICWFLAE----EDMPEV 466
            ...:|         || |:.|...||.          |.|:.:..:||..:.|..    .|:|..
  Rat   439 RTFIS---------ML-CWFAFGFTFY----------GLALDLQALGSNIFLLQALIGIVDLPVK 483

  Fly   467 YGLTLGLLMASLPQAAVACAQSMIL--ACL--GELVPMEQ---RSCLSF-------SAVTWARVW 517
            .|   .||:.|.....:..|.|::|  .|:  ..|||.|.   ||.|:.       :|.|...::
  Rat   484 MG---SLLLLSRLGRRLCQASSLVLPGLCILANILVPREMGILRSSLAVLGLGSLGAAFTCVTIF 545

  Fly   518 QLSASFLTLLRQVSPAL 534
            . |..|.|::|..:..|
  Rat   546 S-SELFPTVIRMTAVGL 561

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4465	NP_650847.1	MFS_SLC22	143..553	CDD:340875	94/423 (22%)
Slc22a12	XP_063125948.1	None