DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG4465 and Balat

DIOPT Version :9

Sequence 1:	NP_650847.1	Gene:	CG4465 / 42374	FlyBaseID:	FBgn0038750	Length:	577	Species:	Drosophila melanogaster
Sequence 2:	NP_610823.1	Gene:	Balat / 36417	FlyBaseID:	FBgn0033778	Length:	604	Species:	Drosophila melanogaster

Alignment Length:	577	Identity:	120/577 - (20%)
Similarity:	227/577 - (39%)	Gaps:	119/577 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    58 DDDVITHIMGNFGPWQ---LRSLLI-------------LFL-------CKIP--AAW-------- 89
            |.|.:...:|:||.:|   :.|:|:             ||:       |::|  ..|
  Fly     2 DFDEVLREVGSFGLYQKVIICSVLLPAALPCAFHAYSQLFIAATPQHFCRVPELEPWTQDYVQLV 66

  Fly    90 ------------FMACILFT--------------APDLYPEEEYKCDTTAFGPDVNSTVSLDHCY 128
                        :..|.:::              .|||..::..  |.....||....|...|.:
  Fly    67 KNLSIPRNRNGAYAECSMYSRNYTDIVRYLEYRPPPDLLRQQAE--DLLKLQPDTTQVVPCQHGW 129

  Fly   129 VMVNYGESAYAMRQCRKFLYTTGFHSLTMEFDLVCLCDFFVAWSQYWHLFGLLIGGVAATKLMRV 193
               :|.:|.|:             .::..|::|||...|.|..:..  :||  :||:....:...
  Fly   130 ---HYDKSIYS-------------STVVQEWNLVCDRSFLVTLALV--VFG--VGGLLGNYVFGY 174

  Fly   194 LSPRQIYRTGIWCLLMCSLLMGLVKDFSLH----CGLRCLAAVSCCFMITSGQYIFGDITAGKYR 254
            |......|...:..|:..::......|:.:    .|||.:..::...::.|...:..::...:.|
  Fly   175 LVDLWGRRPSFYAYLLLEIIACAASAFAWNYYTWLGLRFVVGLTVPAILASPYVLAIELVGPERR 239

  Fly   255 VGTLILYDCFWALGLILLPGLASNAPSWQHIYLGVTLSLLVIVFLLPWTPDSPRWQLQHTKEAQL 319
            |...|:.:..::|||::|.|:......|:.:.|.|::.||::.......|:||||.:...|
  Fly   240 VFCTIVSNIAYSLGLVVLAGVIYIVRDWRELSLAVSMPLLMLFSCFFVLPESPRWLMAVGK---- 300

  Fly   320 AIERTVGILLEAARTNGRMHKVSKELPQQLEE----LRERMLEPMPAVHW--MHLWMG--QRRST 376
             ..|.:.||...||.||  .:|:::..::|:.    .|....:.....|:  :.|:.|  .||.|
  Fly   301 -TRRAIKILKVMARVNG--VRVNRDFVERLQRKLVITRAAETKSSMTTHYGILDLFRGPNMRRKT 362

  Fly   377 FHLVAVHMALATFMVVNTGLLLHVRSFGREHLVSNTLAMGLAEMLGCFLALHLTFNLSERKWQWA 441
            ..:..:..|..:   |..||..:..:.|.:.:.:..|| |..| |..:|.|....:...|:|...
  Fly   363 LIITLIWFANTS---VYVGLSYYAPALGGDEIWNFFLA-GAVE-LPTYLLLWPGLSYFGRRWILF 422

  Fly   442 GGFAIVVGCIGSICWFLAEEDMPEVYGLTLGLLMASLPQAAVACAQSMILACLGELVPMEQRSC- 505
              .:::||.:..:..||    .|::     .||:..:.:..::.:..::.....||.|...|..
  Fly   423 --ISMLVGGVACVATFL----YPDI-----TLLLYCVGKMGISSSFVVLPLMASELYPTVVRGLG 476

  Fly   506 LSFSAVTWARVWQLSASFLTLLRQVSPALSLSAFCLLVILGGLGTCCL-VTRDKEQP 561
            :|||:|. :.|..:....:..:.|....|.|.....|:||||..:..| .||::..|
  Fly   477 MSFSSVI-SMVGPIVIPMINHMGQQMLVLPLIVMGALLILGGFASLLLPETRNRNLP 532

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4465	NP_650847.1	2A0119	67..553	CDD:273328	114/557 (20%)
CG4465	NP_650847.1	MFS	169..>303	CDD:119392	26/137 (19%)
Balat	NP_610823.1	MFS_SLC22	128..524	CDD:340875	94/439 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45458417
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24064
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.940