Protein Alignment CG4465 and Slc22a4

DIOPT Version :9

• Sequence 1: NP_650847.1
• Gene: CG4465 / 42374
• FlyBaseID: FBgn0038750
• Length: 577
• Species: Drosophila melanogaster
• Sequence 2: NP_062661.1
• Gene: Slc22a4 / 30805
• MGIID: 1353479
• Length: 553
• Species: Mus musculus
• Alignment Length: 557
• Identity: 116/557 - (20%)
• Similarity: 214/557 - (38%)
• Gaps: 128/557 - (22%)

  Fly    58 DDDVITHIMGNFGPWQLRSLLILFLCKIPAAWFMACILFTAPDLYPEEEYKCDTTAFGPD-VNST 121
            |.|.:...:|.:||:|.....:|....||..:....::|.|    ...|::|    ..|| ||.:
Mouse     3 DYDEVIAFLGEWGPFQRLIFFLLSASIIPNGFNGMSVVFLA----GTPEHRC----LVPDTVNLS 59

  Fly   122 VSLDHCYVMVNYGESAYAMRQCRKFLYTT---------------------------GFH------ 153
            .|..:..:.:...:.....:.||::...|                           |:.
Mouse    60 SSWRNHSIPLETKDGRQVPQSCRRYRLATIANFSAMGLEPGQDVDLEQLEQESCLDGWEYDKDIF 124

  Fly   154 --SLTMEFDLVCLCDFFVAWSQYWHLFGLLIGGVAATKL------MRVLSPRQIYRTG------- 203
              ::..|::|||..|:....:......|:|.|...:.:|      .:||......:||
Mouse   125 LSTIVTEWNLVCEDDWKTPLTTSLFFVGVLCGSFVSGQLSDRFGRKKVLFATMAVQTGFSFVQIF 189

  Fly   204 -----IWCLLMCSLLMGLVKDFSLHCGLRCLAAVSCCFMITSGQYIFG-DITAGKYRVGTLILYD 262
                 ::.:|...:.||.:.::.:                   .:|.| :|.:...|:....|..
Mouse   190 STNWEMFTVLFAIVGMGQISNYVV-------------------AFILGTEILSKSVRIIFSTLGV 235

  Fly   263 C-FWALGLILLPGLASNAPSWQHIYLGVTLSLLVIVFLLPWTPDSPRWQLQHTK--EAQLAIERT 324
            | |:|:|.::||..|.....|:.:.|.:||..|..|.|..:.|:||||.:...:  ||:..|::
Mouse   236 CTFFAIGYMVLPLFAYFIRDWRMLLLALTLPGLFCVPLWWFIPESPRWLISQRRFAEAEQIIQK- 299

  Fly   325 VGILLEAARTNGRMHKVSKELPQQLEELRERMLEPMPAVHWMHLWMGQRRSTFHLVAVHMALATF 389
                  ||:.|..:.......|.:|:||.....:   .|..:.|:..:..:|..::||.:    :
Mouse   300 ------AAKMNSIVAPAGIFDPLELQELNSLKQQ---KVIILDLFRTRNIATITVMAVML----W 351

  Fly   390 MVVNTG---LLLHVRSF-GREHLVSNTLAMGLAEMLGCFLALHLTFNLSER-----KWQWAGGFA 445
            |:.:.|   |.|:|.:. |..:|  |....||.|:...|.|..|...|..|     ...|.||..
Mouse   352 MLTSVGYFALSLNVPNLHGDVYL--NCFLSGLIEVPAYFTAWLLLRTLPRRYIIAGVLFWGGGVL 414

  Fly   446 IVVGCIGSICWFLAEEDMPEVYG-LTLGLLMASLPQAAVACAQSMILACLGELVPMEQRSCLSFS 509
            :::            :.:||.|. :::||:|  |.:..:..|.||:.....||.|...|:.....
Mouse   415 LLI------------QVVPEDYNFVSIGLVM--LGKFGITSAFSMLYVFTAELYPTLVRNMAVGI 465

  Fly   510 AVTWARVWQLSASFLTLL---RQVSPALSLSAFCLLV 543
            ....:||..:.|.:...|   .::.|.:.:.:..:|:
Mouse   466 TSMASRVGSIIAPYFVYLGAYNRLLPYILMGSLTVLI 502

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4465	NP_650847.1	2A0119	67..553	CDD:273328	114/548 (21%)
		MFS	169..>303	CDD:119392	30/153 (20%)
Slc22a4	NP_062661.1	2A0119	12..519	CDD:273328	114/548 (21%)
		MFS	123..510	CDD:119392	94/429 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167843601
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.840