Protein Alignment CG4465 and Slc22a3

DIOPT Version :9

• Sequence 1: NP_650847.1
• Gene: CG4465 / 42374
• FlyBaseID: FBgn0038750
• Length: 577
• Species: Drosophila melanogaster
• Sequence 2: NP_062103.1
• Gene: Slc22a3 / 29504
• RGDID: 3701
• Length: 551
• Species: Rattus norvegicus
• Alignment Length: 548
• Identity: 136/548 - (24%)
• Similarity: 214/548 - (39%)
• Gaps: 116/548 - (21%)

  Fly    67 GNFGPWQLRSLLILFLCKIPAAWFMACILF--TAPDLY-----------------PEEEYKCDTT 112
            |.||.:|.|..|:|.|..:..|:....::|  :.||.|                 ||||:...|.
  Rat    12 GEFGRFQRRVFLLLCLTGVTFAFLFVGVVFLGSQPDYYWCRGPRATALAERCAWSPEEEWNLTTP 76

  Fly   113 AFG----------------PDVNSTVSLDHCYVMVNYGESAYAMRQCR-KFLYTTGFHSLTMEFD 160
            ...                .|.|::..|. |..:..:...:..:..|. .:.|.....::..:||
  Rat    77 ELHVPAERRGQGHCHRYLLEDTNTSSELS-CDPLAAFPNRSAPLVPCSGDWRYVETHSTIVSQFD 140

  Fly   161 LVC----LCDFFVAWSQYWHLFGLLIGGVAATKLMRVLSPRQIYRTGIWCLLMCSLLMGLVKDFS 221
            |||    :.|...|......|.|....|.||.:..|::    :|....:.:.:..:::....:||
  Rat   141 LVCGNAWMLDLTQAILNLGFLAGAFTLGYAADRYGRLI----VYLISCFGVGITGVVVAFAPNFS 201

  Fly   222 LHCGLRCLAAV------SCCFMITSGQYIFGDITAGKYRVGTLILYDCFWALGLILLPGLASNAP 280
            :....|.|..|      ..||:|.:      :|...|.|....|:...|:.||:|:|||:|...|
  Rat   202 VFVIFRFLQGVFGKGAWMTCFVIVT------EIVGSKQRRIVGIVIQMFFTLGIIILPGIAYFTP 260

  Fly   281 SWQHIYLGVTL-SLLVIVFLLPW-TPDSPRWQLQHTKEAQLAIERTVGILLEAARTNGRMHKVSK 343
            |||.|.|.::| |.|.:::.  | .|:||||.:.. |:.:.|::    ||...|:.||      |
  Rat   261 SWQGIQLAISLPSFLFLLYY--WVVPESPRWLITR-KQGEKALQ----ILRRVAKCNG------K 312

  Fly   344 ELPQQLEELR---ERMLEP--MPAVHWMHLWMGQRRSTFHLVAVHMALATFMVVNTGLLLHVRSF 403
            .|.....|:.   |.:..|  :..|....:    |:.|..|:   .|..|..||..||::.:...
  Rat   313 HLSSNYSEITVTDEEVSNPSCLDLVRTPQM----RKCTLILM---FAWFTSAVVYQGLVMRLGLI 370

  Fly   404 GREHLVSNTLAMGLAEMLGCFLALHLTFNLSERKWQWAGGFAIVVGCIGSICWFLAEEDMPEVYG 468
            | .:|..:....||.|:.|..|.| ||.....|:..:|.. .||.|....:..||.|       |
  Rat   371 G-GNLYMDFFISGLVELPGALLIL-LTIERLGRRLPFAAS-NIVAGVSCLVTAFLPE-------G 425

  Fly   469 LT-LGLLMASLPQAAVACAQSMILACLGELVPMEQRS-----C---LSFSAVTWARVWQLSASFL 524
            :. |...:|:|.:..:..|..::.....||.|...|:     |   ..|..:.        |.||
  Rat   426 IPWLRTTVATLGRLGITMAFEIVYLVNSELYPTTLRNFGVSLCSGLCDFGGII--------APFL 482

  Fly   525 TLLRQVSPALSLSAFCLLVILGGLGTCC 552
             |.|..:..|.|.    |:|.|.|.:.|
  Rat   483 -LFRLAAIWLELP----LIIFGILASVC 505

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4465	NP_650847.1	2A0119	67..553	CDD:273328	136/548 (25%)
		MFS	169..>303	CDD:119392	38/141 (27%)
Slc22a3	NP_062103.1	2A0119	12..523	CDD:273328	136/548 (25%)
		MFS	145..513	CDD:119392	107/414 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166347133
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.840