DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG4465 and CG33233

DIOPT Version :9

Sequence 1:	NP_650847.1	Gene:	CG4465 / 42374	FlyBaseID:	FBgn0038750	Length:	577	Species:	Drosophila melanogaster
Sequence 2:	NP_995978.2	Gene:	CG33233 / 2769005	FlyBaseID:	FBgn0053233	Length:	489	Species:	Drosophila melanogaster

Alignment Length:	520	Identity:	104/520 - (20%)
Similarity:	198/520 - (38%)	Gaps:	132/520 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly   122 VSLDHCYVMVNYGESAYAMRQCRKFLYTTGFHSLTMEFD---LVCL--CDFFVAWSQYWHLFGLL 181
            :.:|...:.:.||.....:.....|:|   .:|:|....   ||.|  |:|..:..:...|...|
  Fly     4 MDVDTALLTIGYGLGQVIIFMVSFFIY---MYSVTESMTAGYLVVLTSCEFDTSPKEKTLLANSL 65

  Fly   182 IGGVAATKL-MRVLSPRQ----IYRTGIWCLLMCSLLMGLVKD-FSLH-------CGLRCLAAVS 233
            :||:.|:.| :..|:.|.    :.|..:...|..|::..|:.| :||.       ..|..:|::.
  Fly    66 LGGMVASGLFIGFLADRYGRKFVIRLALVGALSFSVISALMPDLYSLSVIRIIVGTFLSAVASLQ 130

  Fly   234 CCFMITSGQYIFGDITAGKYRVGTLILYDCFWALGLILLPGLA-SNAPSWQHIYLGVTLSL---- 293
            ..|:        |:..|.|:|..|:.:......|.||..|.:| :..|:..::.|..:.:|
  Fly   131 VGFL--------GEFHAIKWRPITVAICSQSQGLALIYCPLVAMAILPNNFNVDLSSSYNLRVWR 187

  Fly   294 -LVIVFLLP-W--------TPDSPRWQLQHTKEAQLAIERTVGILLEAARTNGRMHKVSKELPQQ 348
             |::.|::| |        .|::|.:        .:::.|....|| |.:...||::      ::
  Fly   188 FLMMFFMIPGWLALVGICLVPETPHF--------LMSVNRPDKALL-ALKWICRMNR------KK 237

  Fly   349 LEELRERMLEPMPAVH-----WMHLWMGQRR--STFHLVAVHMAL-----ATFMVVNTGLLLHV- 400
            .|::...:.|...:.:     |..:|...:.  |..|:....:.|     ..|..:..|:...|
  Fly   238 WEDVDITLSEEKSSTNDQEGFWKTVWYEYKLLFSKPHVFKFFICLFLIFGIFFTSIGLGIWFPVI 302

  Fly   401 RSFGRE------HLVSN--TLAMGLAE----------------------------MLGCFLALHL 429
            |:....      .||:|  |.....|:                            .:|||:...:
  Fly   303 RNMDNSGSNRLCDLVNNNPTFINHEADDTNGTDSESPKCNDEMTNLIDPVYYGFTYIGCFILASV 367

  Fly   430 TFNLSERKWQWAGGFAIVVGCIGSICWFLAEEDMPEVYGLTLGLLMASLPQAAVACAQSMILACL 494
            ..:...||:..|  ..|::..|..|...:.::  |.|. |...:||..||...:..|.|:::.||
  Fly   368 LVHWMTRKYVIA--LHILISMILGISLNIMKQ--PTVV-LIFFVLMMVLPGVLIPLATSVLVDCL 427

  Fly   495 GELVPMEQRS---CLSFSAVTWARVWQLSASFLTLLRQVSPALSLSAF--CLLVILGGLGTCCLV 554
                |:..|.   |:..|...:..|  |.::.:.|..:|:..::.:.|  ||.:        |:|
  Fly   428 ----PVNLRGKALCMVRSLARFGGV--LGSTMIGLFIRVTCDVTFNIFNLCLAI--------CVV 478

Fly 555 554
Fly 479 478

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4465	NP_650847.1	2A0119	67..553	CDD:273328	102/517 (20%)
CG4465	NP_650847.1	MFS	169..>303	CDD:119392	35/161 (22%)
CG33233	NP_995978.2	MFS_1	22..451	CDD:284993	94/465 (20%)
		MFS	23..>208	CDD:119392	44/195 (23%)
		MFS	354..>482	CDD:304372	33/144 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45458147
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24064
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	2.030