Protein Alignment CG4465 and Slc22a22

DIOPT Version :9

• Sequence 1: NP_650847.1
• Gene: CG4465 / 42374
• FlyBaseID: FBgn0038750
• Length: 577
• Species: Drosophila melanogaster
• Sequence 2: XP_036015188.1
• Gene: Slc22a22 / 210463
• MGIID: 2446114
• Length: 587
• Species: Mus musculus
• Alignment Length: 595
• Identity: 126/595 - (21%)
• Similarity: 212/595 - (35%)
• Gaps: 170/595 - (28%)

  Fly    58 DDDVITHIMGNFGPWQLRSLLILFLCKIPAAWFMACILFTA--PDLYPEEEYKCDTTAFGPDVNS 120
            |.|.|.|.:|:.|.:|:..:::|.:..:..:.......|||  |..:.........:....|:|.
Mouse     2 DFDEILHHVGDSGRFQICMIILLNILSLVLSPHDVLENFTAAIPAHHCSINLDNSRSEVSTDMNL 66

  Fly   121 TVSLDHCYVMVNYGESAYAMRQCRKFLYT---------TGFHSLTME------------------ 158
            |.. |...|.:..|.: ....|||:|.||         :.|:|..:|
Mouse    67 TTE-DLMKVSIPMGPN-QKPEQCRRFRYTQWQFLDSNISTFNSTELETEPCLDGWTYDHSVFTST 129

  Fly   159 -------------------------------------FDLVCLCDFFVAWSQYWHLFGLLIGGVA 186
                                                 :||||....|..::|...|.|.|:
Mouse   130 IVTEGLSPPQPWDSDQYYHTKHEISPCEEGLKSSVKVWDLVCDFQSFKYYAQATSLAGHLV---- 190

  Fly   187 ATKLMRVLSPRQIYRTGIWCLLM-CSLLMGLV-------KDFSLHCGLR-CLAAVSCCFMITSGQ 242
            :..|..::|.    |.|...||| |||..|.|       .:||::|.|| .|:|.....:|.|..
Mouse   191 SCPLSGIISD----RFGRKPLLMYCSLAYGAVGTYCAFAPNFSVYCVLRFLLSAFQSTILINSLI 251

  Fly   243 YIFGDITAGKYRVGTLILYDCFWALGLILLPGLASNAPSWQHIYLGVTLSLLVIVFLLPWTPDSP 307
            .:..:.:. ::....::|...|.::|..:|.|||.....|..:.|...|...:...|..|.|:|.
Mouse   252 LVLEEASV-QWHPTIIVLSGLFNSIGQGVLGGLAYVISDWHLLQLAYALPFFIFFVLFCWVPESV 315

  Fly   308 RWQL--QHTKEAQLAIERTVGILLEAARTNGRMHKVSKELPQQL--EELRERMLEPMPAVHWMHL 368
            ||.:  ..|.:|...::|...|       ||:     |.:.|.|  |:||.::.:.:
Mouse   316 RWLIITGKTDQAWKELQRIASI-------NGK-----KGIAQNLTTEDLRSKLKKDV-------- 360

  Fly   369 WMGQRRSTFHL-----VAVHMALATFMVVNT-----------GLLLHVRSFGREHLVSNTLAMGL 417
                 .||..|     :.::..:...::.|:           ||||.|:..|:...::. :.:|.
Mouse   361 -----NSTGKLFRIKDIFINPLIRKIVLSNSSLLFAELFSFVGLLLDVQLLGKNMFLTQ-IFLGA 419

  Fly   418 AEMLGCFLALHLTFNLSERKWQWAGGFAIVVGCIGSICWFLAEEDMPEVYGL-TLGLLMASLPQA 481
            .::....|......|:|.|  .......:..|...:|..|::|    |:|.| |:..::.....|
Mouse   420 IDVPSKSLTYFTIRNVSRR--PLIAFLLLTTGSCITITIFISE----EMYVLRTIIFILGKGCFA 478

  Fly   482 AVACAQSMILACLGELVPMEQRSCLSFSAVTWARVWQLSASFLTLLRQVSPALSLSAFCLLVILG 546
            |..|..:   ..:.||.|:|.||             .|:..||.::|               :.|
Mouse   479 AFTCIST---TYINELSPVELRS-------------TLNGVFLAVVR---------------LAG 512

  Fly   547 GLGTCCLVTR 556
            .|....|.||
Mouse   513 VLSALTLATR 522

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4465	NP_650847.1	2A0119	67..553	CDD:273328	119/581 (20%)
		MFS	169..>303	CDD:119392	36/142 (25%)
Slc22a22	XP_036015188.1	MFS_OAT	108..548	CDD:340932	100/487 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167843671
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.840