Protein Alignment CG4465 and Slc22a12

DIOPT Version :9

• Sequence 1: NP_650847.1
• Gene: CG4465 / 42374
• FlyBaseID: FBgn0038750
• Length: 577
• Species: Drosophila melanogaster
• Sequence 2: NP_033229.3
• Gene: Slc22a12 / 20521
• MGIID: 1195269
• Length: 553
• Species: Mus musculus
• Alignment Length: 535
• Identity: 109/535 - (20%)
• Similarity: 186/535 - (34%)
• Gaps: 146/535 - (27%)

  Fly    66 MGNFGPWQLRSLLILFLCKIPAAW---------FMACILFTAPDLYPEEEYKC------DTTA-- 113
            :|..|.:||...:.|.   .|..|         |.|.:          ..::|      ::|:
Mouse    10 VGGLGRFQLFQTVALV---TPILWVTTQNMLENFSAAV----------PHHRCWVPLLDNSTSQA 61

  Fly   114 -----FGPDVNSTVSL--------DHCY--------------VMVNYGESAYAMRQCRK---FLY 148
                 .||||...||:        ..|.              ...|:.::  |...|..   :.:
Mouse    62 SIPGDLGPDVLLAVSIPPGPDQQPHQCLRFRQPQWQLTESNATATNWSDA--ATEPCEDGWVYDH 124

  Fly   149 TTGFHSLTMEFDLVCLCDFFVAWSQYWHLFGLLIG----GVAATKL--MRVLSPRQIYRTGIWCL 207
            :|...::...:||||........:|...|.|:|:|    |.|:.:.  .|||:         |..
Mouse   125 STFRSTIVTTWDLVCNSQALRPMAQSIFLAGILVGAAVCGHASDRFGRRRVLT---------WSY 180

  Fly   208 LMCSL---LMGLVKDFSLHCGLRCLAAVSCCFMITSGQYIFGDITAGKYRVGTLILYDCFWALGL 269
            |:.|:   ....:..|.|:|..|.|.|.:...::.:...:..:.|:.:.....:.|....::.|.
Mouse   181 LLVSVSGTAAAFMPTFPLYCLFRFLLASAVAGVMMNTASLLMEWTSAQGSPLVMTLNALGFSFGQ 245

  Fly   270 ILLPGLASNAPSWQHIYLGVTLSLLVIVFLLPWTPDSPRWQL------QHTKEAQ--LAIER--- 323
            :|...:|....||:.:.|.|:....:......|.|:|.||.:      |..:|.|  .|:.|
Mouse   246 VLTGSVAYGVRSWRMLQLAVSAPFFLFFVYSWWLPESARWLITVGKLDQGLQELQRVAAVNRRKA 310

  Fly   324 -----TVGILLEAARTNGRMHKVSKELPQQLEE--LRERMLEPMPAVHWMHLWMGQRRSTFHLVA 381
                 |:.:|..|........|....|...|..  ||.|.:..|  :.|.....     ||:.:|
Mouse   311 EGDTLTMEVLRSAMEEEPSRDKAGASLGTLLHTPGLRHRTIISM--LCWFAFGF-----TFYGLA 368

  Fly   382 VHM-ALAT--FMV----------VNTGLLLHVRSFGREHL-VSNTLAMGLAEMLGCFLALHLTFN 432
            :.: ||.:  |::          |.||.||.:...||... ||..:..||. :|...|..|
Mouse   369 LDLQALGSNIFLLQALIGIVDFPVKTGSLLLISRLGRRLCQVSFLVLPGLC-ILSNILVPH---- 428

  Fly   433 LSERKWQWAGGFAIV--------VGCIG---SICWFLAEEDMPEVYGLT-LGLLMASLPQAAVAC 485
                      |..::        :||:|   :.....:.|..|.|..:| :||...:....|:..
Mouse   429 ----------GMGVLRSALAVLGLGCLGGAFTCITIFSSELFPTVIRMTAVGLCQVAARGGAMLG 483

  Fly   486 AQSMILACLGELVPM 500
            ....:|...|..:|:
Mouse   484 PLVRLLGVYGSWMPL 498

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4465	NP_650847.1	2A0119	67..553	CDD:273328	109/534 (20%)
		MFS	169..>303	CDD:119392	28/142 (20%)
Slc22a12	NP_033229.3	2A0119	11..526	CDD:273328	109/534 (20%)
		MFS	147..516	CDD:119392	83/383 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167843311
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.930