Protein Alignment CG4465 and Slc22a5

DIOPT Version :10

• Sequence 1: NP_650847.1
• Gene: CG4465 / 42374
• FlyBaseID: FBgn0038750
• Length: 577
• Species: Drosophila melanogaster
• Sequence 2: NP_035526.1
• Gene: Slc22a5 / 20520
• MGIID: 1329012
• Length: 557
• Species: Mus musculus
• Alignment Length: 563
• Identity: 111/563 - (19%)
• Similarity: 214/563 - (38%)
• Gaps: 139/563 - (24%)

  Fly    58 DDDVITHIMGNFGPWQLRSLLILFLCKIPAAWFMACILFTAPDLYPEEEYKCDTTAFGPDVNSTV 122
            |.|.:|..:|.:||:|.....:|....||..:....|:|.|    ...|::|       .|..||
Mouse     3 DYDEVTAFLGEWGPFQRLIFFLLSASIIPNGFNGMSIVFLA----GTPEHRC-------LVPHTV 56

  Fly   123 SLDHCY----VMVNYGESAYAMRQCRKFLYTT---------------------------GFH--- 153
            :|...:    :.:...:.....::||::...|                           |:.
Mouse    57 NLSSAWRNHSIPLETKDGRQVPQKCRRYRLATIANFSELGLEPGRDVDLEQLEQESCLDGWEYDK 121

  Fly   154 -----SLTMEFDLVCLCDFFVAWSQYWHLFGLLIGGVAATKLMRVLSPRQIYRTGIWCLLMCSLL 213
                 ::..|:||||..|:....:......|:|:|...:.:|......:.:          ..|.
Mouse   122 DVFLSTIVTEWDLVCKDDWKAPLTTSLFFVGVLMGSFISGQLSDRFGRKNV----------LFLT 176

  Fly   214 MGLVKDFSLHCGLRCLAAVSCCF--------MITSGQ-------YIFG-DITAGKYRVGTLILYD 262
            ||:...||.      |...|..|        ::..||       ::.| :|.:...|:....|..
Mouse   177 MGMQTGFSF------LQVFSVNFEMFTVLFVLVGMGQISNYVAAFVLGTEILSKSIRIIFATLGV 235

  Fly   263 C-FWALGLILLPGLASNAPSWQHIYLGVTLSLLVIVFLLPWTPDSPRWQLQ--HTKEAQLAIERT 324
            | |:|.|.::||..|.....|:.:.|.:|:..::...|..:.|:||||.:.  ..|||::
Mouse   236 CIFYAFGFMVLPLFAYFIRDWRMLLLALTVPGVLCGALWWFIPESPRWLISQGRIKEAEV----- 295

  Fly   325 VGILLEAARTNGRMHKVSKELPQQLEELRERMLEPMPAVHWMHLWMGQRRSTFHLVAVHMALATF 389
              |:.:||:.||.:...:...|.:|::|.    ...|.:|  |::...|.....::.: |::..:
Mouse   296 --IIRKAAKINGIVAPSTIFDPSELQDLN----STKPQLH--HIYDLIRTRNIRVITI-MSIILW 351

  Fly   390 MVVNTGLLLHVRSFGREHLVSNTLAMGLAEMLG-----CFLALHLTFNLSERKW--------QWA 441
            :.::.|.      ||        |::....:.|     |||...:........|        :::
Mouse   352 LTISVGY------FG--------LSLDTPNLHGDIYVNCFLLAAVEVPAYVLAWLLLQYLPRRYS 402

  Fly   442 GGFAIVVGCIGSICWFLAEEDMP-EVYGLTLGLLMASLPQAAVACAQSMILACLGELVPMEQRSC 505
            ...|:.:|  ||:..|:  :.:| |::.|:..|:|..  :..:..|.||:.....||.|...|:.
Mouse   403 ISAALFLG--GSVLLFM--QLVPSELFYLSTALVMVG--KFGITSAYSMVYVYTAELYPTVVRNM 461

  Fly   506 LSFSAVTWARVWQLSASFLTLLRQVSPALSLSAFCLLVILGGL 548
            ....:.|.:|:..:.:.:...|.      :...|...:::|.|
Mouse   462 GVGVSSTASRLGSILSPYFVYLG------AYDRFLPYILMGSL 498

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4465	NP_650847.1	MFS_SLC22	143..553	CDD:340875	92/474 (19%)
Slc22a5	NP_035526.1	2A0119	12..520	CDD:273328	108/554 (19%)