Protein Alignment CG4465 and Slc22a2

DIOPT Version :9

• Sequence 1: NP_650847.1
• Gene: CG4465 / 42374
• FlyBaseID: FBgn0038750
• Length: 577
• Species: Drosophila melanogaster
• Sequence 2: NP_038695.1
• Gene: Slc22a2 / 20518
• MGIID: 1335072
• Length: 553
• Species: Mus musculus
• Alignment Length: 573
• Identity: 118/573 - (20%)
• Similarity: 208/573 - (36%)
• Gaps: 124/573 - (21%)

  Fly    59 DDVITHIMGNFGPWQLRSLLILFL----------------------CKIP--------AAWFMAC 93
            ||::.|| |.|..:|.::..:|.|                      |:.|        ..|..|.
Mouse     5 DDILEHI-GEFHLFQKQTFFLLALLSGAFTPIYVGIVFLGFTPNHHCRSPGVAELSQRCGWSPAE 68

  Fly    94 IL-FTAPDLYPEEE---------YKCD---TTAFGPDVNSTVSLDHCYVMVNYGESAYAMRQCRK 145
            .| :|.|.|....|         |:.|   :|....|..|:::.:..::.::..|..:
Mouse    69 ELNYTVPGLGSAGEVSFLSQCMRYEVDWNQSTLDCVDPLSSLAANRSHLPLSPCEHGW------- 126

  Fly   146 FLYTTGFHSLTMEFDLVCLCDFFVAWSQYWHLFGLLIGGVAATKLMRVLSPRQIYRTGIWCLLMC 210
             :|.|...|:..||:|||...:.:...|.....|..||.|....|......:       :|||:.
Mouse   127 -VYDTPGSSIVTEFNLVCAHSWMLDLFQSLVNVGFFIGAVGIGYLADRFGRK-------FCLLVT 183

  Fly   211 SL-------LMGLVKDFSLHCGLRCLAAVSCCFMITSGQYIFGDITAGK-----YRVGTLILYDC 263
            .|       ||.:..:::.....|.|..     :::...::.|.|...:     ||....|.|..
Mouse   184 ILINAISGVLMAISPNYAWMLVFRFLQG-----LVSKAGWLIGYILITEFVGLGYRRTVGICYQI 243

  Fly   264 FWALGLILLPGLASNAPSWQHIYLGVTLSLLVIVFLLPWTPDSPRWQLQHTKEAQLAIERTVGIL 328
            .:.:||::|.|:|...|:|:.:...|||.....:......|:||||.:...|.|     :.:.|:
Mouse   244 AFTVGLLILAGVAYALPNWRWLQFAVTLPNFCFLLYFWCIPESPRWLISQNKNA-----KAMKII 303

  Fly   329 LEAARTNGRMHKVS------------KELPQQLEELRERMLEPMPAVHWMHLWMGQRRSTFHLVA 381
            ...|:.||:...||            |..|..|:.:|...:.....: .|:.|.
Mouse   304 KHIAKKNGKSVPVSLQSLTADEDTGMKLNPSFLDLVRTPQIRKHTLI-LMYNWF----------- 356

  Fly   382 VHMALATFMVVNTGLLLHVRSFGREHLVSNTLAMGLAEMLGCFLALHLTFNLSERKWQWA-GGFA 445
                  |..|:..||::|:...| :::..:.....|.|....|:.: ||.:...|::.|| ....
Mouse   357 ------TSSVLYQGLIMHMGLAG-DNIYLDFFYSALVEFPAAFIII-LTIDRIGRRYPWAVSNMV 413

  Fly   446 IVVGCIGSICWFLAEEDMPEVYGLTLGLLMASLPQAAVACAQSMILACLGELVPMEQRSCLSFSA 510
            ....|:.|:   ...:|:.     .|.:.:|.|.:..:..|..|:.....||.|...|:......
Mouse   414 AGAACLASV---FIPDDLQ-----WLKITVACLGRMGITIAYEMVCLVNAELYPTYIRNLAVLVC 470

  Fly   511 VTWARVWQLSASFLTL-LRQVSPALSLSAFCLL-VILGGLGTCCLVTRDKEQP 561
            .:...:..:...||.. |..:.....|..|.:: ::.|||......|:.|..|
Mouse   471 SSMCDIGGIVTPFLVYRLTDIWLEFPLVVFAVVGLVAGGLVLLLPETKGKALP 523

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4465	NP_650847.1	2A0119	67..553	CDD:273328	111/555 (20%)
		MFS	169..>303	CDD:119392	30/145 (21%)
Slc22a2	NP_038695.1	2A0119	12..525	CDD:273328	114/565 (20%)
		MFS	125..492	CDD:119392	86/419 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167843589
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.840