Protein Alignment CG4465 and Slc22a1

DIOPT Version :9

• Sequence 1: NP_650847.1
• Gene: CG4465 / 42374
• FlyBaseID: FBgn0038750
• Length: 577
• Species: Drosophila melanogaster
• Sequence 2: NP_033228.2
• Gene: Slc22a1 / 20517
• MGIID: 108111
• Length: 556
• Species: Mus musculus
• Alignment Length: 560
• Identity: 128/560 - (22%)
• Similarity: 214/560 - (38%)
• Gaps: 139/560 - (24%)

  Fly    59 DDVITHIMGNFGPWQLRSLLILFLCKIPAAWFMACILFT--APDLY------PEEEYKCDTTAFG 115
            |||:.|: |.||.:|.::.|:|.|.....|.....|:|.  .||.:      .|...:|   .:.
Mouse     5 DDVLEHV-GEFGWFQKQAFLLLCLISASLAPIYVGIVFLGFTPDHHCRSPGVAELSQRC---GWS 65

  Fly   116 P--DVNSTVSLDHCYVMVNYGESAYAMRQCRKF-------------------------------- 146
            |  ::|.||.     .:.:.||::: :.||.|:
Mouse    66 PAEELNYTVP-----GLGSAGEASF-LSQCMKYEVDWNQSTLDCVDPLSSLAANRSHLPLSPCEH 124

  Fly   147 --LYTTGFHSLTMEFDLVC----LCDFFVAWSQYWHLFGLLIGGVAATKLMRVLSPRQIYRTGIW 205
              :|.|...|:..||:|||    ..|.|.:........|.|:.|..|.:..|.|
Mouse   125 GWVYDTPGSSIVTEFNLVCGDAWKVDLFQSCVNLGFFLGSLVVGYIADRFGRKL----------- 178

  Fly   206 CLLMCSL-------LMGLVKDFSLHCGLRCLAAVSCCFMITSGQYIFG-----DITAGKYRVGTL 258
            |||:.:|       |..:..|::.....|.|..     |::.|.::.|     :.....||..|.
Mouse   179 CLLVTTLVTSLSGVLTAVAPDYTSMLLFRLLQG-----MVSKGSWVSGYTLITEFVGSGYRRTTA 238

  Fly   259 ILYDCFWALGLILLPGLASNAPSWQHIYLGVTLSLLVIVFLLPWTPDSPRWQLQHTKEAQLAIER 323
            |||...:.:||:.|.|:|...|.|:.:.|.|:|...:.:....:.|:||||.|...:..|
Mouse   239 ILYQVAFTVGLVGLAGVAYAIPDWRWLQLAVSLPTFLFLLYYWFVPESPRWLLSQKRTTQ----- 298

  Fly   324 TVGILLEAARTNGRMHKVSKELPQQLEELRERMLEPMPAVHWMHLWMGQRRSTFHLVAVHMALAT 388
            .|.|:.:.|:.|.::.....::....|:..||.   .|:...:......|:.|..|:.:..:.|
Mouse   299 AVRIMEQIAQKNRKVPPADLKMMCLEEDASERR---SPSFADLFRTPSLRKHTLILMYLWFSCA- 359

  Fly   389 FMVVNTGLLLHVRSFGREHLVSNTLAMGLAEMLGCFLALHLTFNLSERKWQWAGGFAIVVGCIGS 453
              |:..||::||.:.| .:|..:.....|.|....|:.| :|.:...|.:..|....:.    |:
Mouse   360 --VLYQGLIMHVGATG-ANLYLDFFYSSLVEFPAAFIIL-VTIDRIGRIYPIAASNLVA----GA 416

  Fly   454 ICWFLAEEDMPEVYGLTLGLLMASLPQAAVACAQSMILACLGEL--VPMEQRSCLSFSAVTWARV 516
            .|                 |||..:|......  ::.|||||.:  ..:.|..||..:.:
Mouse   417 AC-----------------LLMIFIPHELHWL--NVTLACLGRMGATIVLQMVCLVNAEL----- 457

  Fly   517 WQLSASFLTLLRQVSPALSLSAFCLLVILGGLGTCCLVTR 556
                  :.|.:|.:. .:..||.|   .|||:.|..:|.|
Mouse   458 ------YPTFIRNLG-MMVCSALC---DLGGIFTPFMVFR 487

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4465	NP_650847.1	2A0119	67..553	CDD:273328	122/547 (22%)
		MFS	169..>303	CDD:119392	33/145 (23%)
Slc22a1	NP_033228.2	2A0119	12..525	CDD:273328	124/552 (22%)
		MFS	125..515	CDD:119392	101/430 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167843613
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D704438at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.850